Prebiotic Factors Influencing the Activity of a Ligase Ribozyme by Fabrizio Anella, Christophe Danelon

“…However, a full narrative to form such RNA protocells implies that catalytic RNA molecules, called ribozymes, can operate in the presence of self-assembled vesicles composed of prebiotically relevant constituents, such as fatty acids. …”
Get full text

Design principles for ligand-sensing, conformation-switching ribozymes. by Xi Chen, Andrew D Ellington

“…A number of ligand-sensing, conformational-switching ribozymes (also known as allosteric ribozymes or aptazymes) have been generated by some combination of directed evolution or rational design. …”
Get full text

Modulation of Group I Ribozyme Activity by Cationic Porphyrins by Shigeyoshi Matsumura, Tatsunobu Ito, Takahiro Tanaka, Hiroyuki Furuta, Yoshiya Ikawa

Subjects: Get full text

Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly by Saurja DasGupta, Stephanie Zhang, Jack W. Szostak

Get full text

RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers by Thodima Venkata, Pirooznia Mehdi, Deng Youping

“…<p>Abstract</p> <p>Background</p> <p>Catalytic RNA molecules are called ribozymes. The aptamers are DNA or RNA molecules that have been selected from vast populations of random sequences, through a combinatorial approach known as SELEX. …”

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes by Ki-Young Lee, Bong-Jin Lee

Subjects: “…novel ribozymes…”
Get full text

RNA ligase ribozymes with a small catalytic core by Yoko Nomura, Yohei Yokobayashi

“…Many natural ribozymes and laboratory evolved ribozymes exhibit efficient catalysis mediated by elaborate catalytic cores within complex tertiary structures. …”
Get full text

Kinetic barriers to folding in the Tetrahymena group I ribozyme by Rook, Martha S. (Martha Sanderson), 1970-

Get full text

Ribozyme-mediated trans-splicing of a trinucleotide repeat. by Phylactou, L, Darrah, C, Wood, M

“…Ribozyme-mediated RNA repair may thus form a novel therapeutic strategy for diseases associated with repeat expansions.…”

OPTIMIZING HAMMERHEAD RIBOZYMES FOR USE AGAINST HIV IN-VIVO by Thompson, S, Griffin, P, James, W

Ribozymes and siRNA for the treatment of diseases of the nervous system. by Wood, M, Trülzsch, B, Abdelgany, A, Beeson, D

“…Naturally occurring catalytic RNA molecules (ribozymes), their synthetic DNA counterparts (deoxyribozymes or DNAzymes), as well as the exciting, emerging technology of small interfering RNA which utilizes the highly conserved cellular RNA interference pathway, are being developed for therapeutic gene silencing purposes. …”

An RNA Triangle with Six Ribozyme Units Can Promote a <i>Trans</i>-Splicing Reaction through Trimerization of Unit Ribozyme Dimers by Junya Akagi, Takahiro Yamada, Kumi Hidaka, Yoshihiko Fujita, Hirohide Saito, Hiroshi Sugiyama, Masayuki Endo, Shigeyoshi Matsumura, Yoshiya Ikawa

Subjects: Get full text

Reconciling Ligase Ribozyme Activity with Fatty Acid Vesicle Stability by Fabrizio Anella, Christophe Danelon

“…Here, we report on the activity of a short L1 ligase ribozyme in the presence of myristoleic acid (MA) vesicles at varying concentrations of Mg2+. …”
Get full text

Investigating a new generation of ribozymes in order to target HCV. by Michel V Lévesque, Dominique Lévesque, Francis P Brière, Jean-Pierre Perreault

“…These ribozymes resulted from the coupling of a specific on/off adaptor (SOFA) to the ribozyme domain derived from the Hepatitis Delta Virus (HDV). …”
Get full text

Ribozyme activity modulates the physical properties of RNA–peptide coacervates by Kristian Kyle Le Vay, Elia Salibi, Basusree Ghosh, TY Dora Tang, Hannes Mutschler

Subjects: “…ribozyme…”
Get full text

The Hammerhead Ribozyme: A Long History for a Short RNA by Marcos de la Peña, Inmaculada García-Robles, Amelia Cervera

“…The hammerhead ribozyme was the first reported and the most extensively studied member of this family. …”
Get full text

Aptamers, Riboswitches, and Ribozymes in <i>S. cerevisiae</i> Synthetic Biology by Huanhuan Ge, Mario Andrea Marchisio

Subjects: Get full text

Co-Localization of Hammerhead Ribozymes and HIV RNA’s by Rev Multimerization by Yüksel YILDIZ, John J. ROSSI

Subjects: Get full text

RNA Synthesis by in Vitro Selected Ribozymes for Recreating an RNA World by Lyssa L. Martin, Peter J. Unrau, Ulrich F. Müller

Subjects: Get full text

Slowing down a hammerhead ribozyme allows glimpses of it in action. by Robin Meadows

Get full text