Protocol to monitor cardiac function and hemodynamics in septic rodents by Binbin Meng, Xinrun Wang, Li Li, Haisong Zhang, Wenchao Li, Zhonghua Hu, Lina Zhang, Zhaoxin Qian

“…Here, we present a protocol to monitor cardiac function and hemodynamics in septic rodents. We describe steps for performing cecal ligation and puncture on rodents to induce sepsis, acquiring two-dimensional echocardiographic and M-mode ultrasonic images, and assessing mean arterial pressure in septic animals.For complete details on the use and execution of this protocol, please refer to Zhang et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Rodent Assemblages in the Mosaic of Habitat Types in the Zambezian Bioregion by Vincent R. Nyirenda, Ngawo Namukonde, Matamyo Simwanda, Darius Phiri, Yuji Murayama, Manjula Ranagalage, Kaula Milimo

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Instrumented swim test for quantifying motor impairment in rodents by Natasha C. Hughes, Dale C. Roberts, Basile Tarchini, Kathleen E. Cullen

“…Abstract Swim tests are highly effective for identifying vestibular deficits in rodents by offering significant vestibular motor challenges with reduced proprioceptive input, unlike rotarod and balance beam tests. …”
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Rodent models of Parkinson’s disease: beyond the motor symptomatology by Filipa Lopes Campos, Filipa Lopes Campos, Miguel M Carvalho, Miguel M Carvalho, Ana C Cristovão, Ana C Cristovão, Goun eJe, Graça eBaltazar, António J Salgado, António J Salgado, Yoon-Seong eKim, Nuno eSousa, Nuno eSousa

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Effect of feed restriction on learning, memory and stress of rodents by Frederico Rogerio Ferreira, Vanessa Beatriz Monteiro Galassi Spini, Ederaldo Jose Lopes, Renata Ferraz Fernandes Lopes, Eduardo Antonio Moreira, Marco Antonio Franco Amaral, Ana Lucia Lucia Souto Cunha, Ana Paula de Souza Borges, Luciane Borges Marson, Gabriel de Camargos Cunha Ribeiro

“…The aim of the present study was to evaluate the FR effects in CNS superior functions focusing in learning and memory in rodent models. Male Wistar rats were divided into three groups (n = 9/group) according to dietary conditions: ad libitum (AL) with unlimited access to standard rat diet (22% of protein, 8% fiber, 4% fat, 10% minerals, 1.4% Calcium, 0.8% Phosphorus); FR30 and FR60 groups were fed with 70% and 40%, respectively, of total rat diet offered to the AL group for 15 weeks. …”
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Histological E-data Registration in rodent Brain Spaces by Jingyi Guo Fuglstad, Pearl Saldanha, Jacopo Paglia, Jonathan R Whitlock

“…Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. …”
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Lipidoid mRNA nanoparticles for myocardial delivery in rodents by Turnbull, IC, Eltoukhy, AA, Anderson, DG, Costa, KD

“…Here we describe the use of lipidoid nanoparticles for delivery of modified mRNA (modRNA) to the myocardium in vivo, with a focus on rodent models that represent a first step toward preclinical studies. …”
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Neuronal expression of muskelin in the rodent central nervous system by Tagnaouti, Nadia, Loebrich, Sven, Heisler, Frank F, Pechmann, Yvonne, Fehr, Susanne, De Arcangelis, Adele, Georges-Labouesse, Elisabeth, Adams, Josephine C, Kneussel, Matthias, Loebrich, Sven

“…Since little is known about muskelin in neuronal tissues, we here analysed the tissue distribution of muskelin in rodent brain and analysed its subcellular localization using cultured neurons from multiple life stages. …”
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In vivo Optogenetic Stimulation of the Rodent Central Nervous System by Sidor, Michelle M., Davidson, Thomas J., Warden, Melissa R., Diesseroth, Karl, McClung, Colleen A., Tye, Kay

“…The current protocol describes delivery of specific wavelengths of light to opsin-expressing cells in deep brain structures of awake, freely-moving rodents for neural circuit modulation. Theoretical principles of light transmission as an experimental consideration are discussed in the context of performing in vivo optogenetic stimulation. …”
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Depth sensitive Raman spectroscopy for skin wounds in rodents by Su, Joshua Weiming, Wang, Qiang, Tian, Yao, Madden, Leigh, Teo, Erica Mei Ling, Becker, David Laurence, Liu, Quan

“…Considering the critical importance of rodent studies in the field of skin wound assessment, it is necessary to develop and validate a system that can perform depth sensitive measurements in rat skin with a proper target depth range. …”
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Transplantation tolerance: lessons from experimental rodent models. by Kingsley, C, Nadig, SN, Wood, K

“…Over the past 50 years, rodent models have become an invaluable tool for elucidating the mechanisms of tolerance to alloantigens. …”

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi. by Reece, SE, Duncan, AB, West, SA, Read, A

“…Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi. First we test the accuracy of empirical methods for estimating sex ratios in malaria parasites, and show that sex ratios made with standard thin smears may overestimate the proportion of female gametocytes. …”

The clinical epidemiology of scrub typhus in humans, chiggers and rodents by Elliott, I

Weighted cue integration in the rodent head direction system. by Knight, R, Piette, C, Page, H, Walters, D, Marozzi, E, Nardini, M, Stringer, S, Jeffery, K

Regulatory T cells--a journey from rodents to the clinic. by Long, E, Wood, K

“…This review will focus on how rodent experimental models have helped us to figure out how Tregs could be induced in humans and harnessed to enable long-term transplant acceptance.…”

Restricted expression of Slap-1 in the rodent cerebral cortex. by Alifragis, P, Molnár, Z, Parnavelas, J

Sleep and ageing: from human studies to rodent models by McKillop, LE, Vyazovskiy, VV

“…Importantly, in contrast to human studies, evidence from laboratory rodents suggests that sleep duration is increased with ageing, while evidence for reduced sleep intensity and consolidation is inconsistent. …”

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi by Reece, SE, Duncan, AB, West, SA, Read, A

“…Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi. First we test the accuracy of empirical methods for estimating sex ratios in malaria parasites, and show that sex ratios made with standard thin smears may overestimate the proportion of female gametocytes. …”

Arenavirus diversity and phylogeography of Mastomys natalensis rodents, Nigeria by Olayemi, A, Obadare, A, Oyeyiola, A, Igbokwe, J, Fasogbon, A, Igbahenah, F, Ortsega, D, Asogun, D, Umeh, P, Vakkai, I, Abejegah, C, Pahlman, M, Becker-Ziaja, B, Günther, S, Fichet-Calvet, E

“…Mastomys natalensis rodents are natural hosts for Lassa virus (LASV). …”

Strategies for mapping and cloning quantitative trait genes in rodents. by Flint, J, Valdar, W, Shifman, S, Mott, R

“…We review the potential of these strategies to identify genes that underlie QTLs in rodents.…”