Clinical Outcomes of Percutaneous Transforaminal Endoscopic Discectomy Assisted with Selective Nerve Root Block for Treating Radicular Pain with Diagnostic Uncertainty in the Elder... by Zhu Y, Zhang X, Gu G, Fan Y, Zhou Z, Feng C, Gu X, He S

“…Radiological findings showed that 80.6% of the patients with multilevel disc herniation, 16.7% received lumbar fusion surgery before, and 8.3% with degenerative scoliosis. Besides, 69.4% of the patients have at least one comorbidity. 85.4% of the patients showed a positive response to selective nerve root block, and 91.6% of the patients reported a favorable outcome at the last follow-up. …”
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Preoperative Malnutrition-Associated Spinal Malalignment with Patient-Reported Outcome Measures in Adult Spinal Deformity Surgery: A 2-Year Follow-Up Study by Jili Wang, Shin Oe, Yu Yamato, Tomohiko Hasegawa, Go Yoshida, Tomohiro Banno, Hideyuki Arima, Yuki Mihara, Koichiro Ide, Yuh Watanabe, Keiichi Nakai, Kenta Kurosu, Yukihiro Matsuyama

“…Demographic data, medical complications, mechanical complications, radiographic parameters, Oswestry Disability Index (ODI), and Scoliosis Research Society-22 (SRS-22) were analyzed. …”
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Co-occurring conditions in children with Down syndrome and autism: a retrospective study by Noemi A. Spinazzi, Jonathan D. Santoro, Katherine Pawlowski, Gabriel Anzueto, Yamini J. Howe, Lina R. Patel, Nicole T. Baumer

“…Individuals with DS+ASD were more likely to be male (OR 2.23, CI 1.29–3.84) and had higher odds of a current or prior diagnosis of constipation (OR 2.19, CI 1.31–3.65), gastroesophageal reflux (OR 1.91, CI 1.14–3.21), behavioral feeding difficulties (OR 2.71, CI 1.02–7.19), infantile spasms (OR 6.03, CI 1.79–20.34) and scoliosis (OR 2.73, CI 1.16–6.40). There were lower odds of congenital heart disease in the DS+ASD group (OR 0.56, CI 0.34–0.93). …”
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Novel Genetic and Phenotypic Expansion in <i>GOSR2</i>-Related Progressive Myoclonus Epilepsy by Lea Hentrich, Mered Parnes, Timothy Edward Lotze, Rohini Coorg, Tom J. de Koning, Kha M. Nguyen, Calvin K. Yip, Heinz Jungbluth, Anne Koy, Hormos Salimi Dafsari

“…Typical clinical features include ataxia and areflexia during early childhood, followed by seizures, scoliosis, dysarthria, and myoclonus. Here, we report two novel patients from unrelated families with a <i>GOSR2</i>-related disorder and novel genetic and clinical findings. …”
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Staged osteotomy in lateral position for the treatment of severe kyphotic deformity secondary to ankylosing spondylitis: a retrospective study by Zhengjun Hu, Rui Zhong, Deng Zhao, Fei Wang, Huaqiang Huang, Dengxu Jiang, Zhong Zhang, Yijian Liang

“…Global kyphosis (GK), thoracic kyphosis (TK), lumbar lordosis (LL), sagittal vertical axis (SVA), osteotomized vertebra intervertebral angle (OVI), chin-brow vertical angle (CBVA), Oswestry Disability Index (ODI) score and Scoliosis Research Society-22 Patient Questionnaire (SRS-22) were all compared pre- and postoperation. …”
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MPS VII – Extending the classical phenotype by A. Oldham, N.J. Oxborrow, P. Woolfson, P. Jenkins, C. Gadepalli, J. Ashworth, A. Saxena, M. Rothera, C.J. Hendriksz, G. Tol, A. Jovanovic

“…The patient presented with a history of developmental delay, scoliosis, kyphosis, corneal clouding, abnormal gait, short stature, hearing impairment, slightly coarse facial features and progressive deterioration of fine motor skills since childhood. …”
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Surgical appropriateness nudges: Developing behavioral science nudges to integrate appropriateness criteria into the decision making of spine surgeons. by Teryl K Nuckols, Peggy G Chen, Kanaka D Shetty, Harsimran S Brara, Neel Anand, Nabeel Qureshi, David L Skaggs, Jason N Doctor, Joshua M Pevnick, Anne F Mannion, Surgical Appropriateness Nudge Authorship Group

“…We sought to design "surgical appropriateness nudges" to support routine use of appropriateness criteria for degenerative lumbar scoliosis and spondylolisthesis.<h4>Methods</h4>The work reflected Stage I of the NIH Stage Model for Behavioral Intervention Development and involved an iterative, multi-method approach, emphasizing qualitative methods. …”
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The role of RIM in neurotransmitter release: promotion of synaptic vesicle docking, priming, and fusion by Shanshan Wu, Shanshan Wu, Jiali Fan, Jiali Fan, Fajuan Tang, Fajuan Tang, Lin Chen, Lin Chen, Xiaoyan Zhang, Xiaoyan Zhang, Dongqiong Xiao, Dongqiong Xiao, Xihong Li, Xihong Li

“…In addition, abnormal expression of RIM has been detected in many diseases, such as retinal diseases, Asperger’s syndrome (AS), and degenerative scoliosis. Therefore, we believe that studying the molecular structure of RIM and its role in neurotransmitter release will help to clarify the molecular mechanism of neurotransmitter release and identify targets for the diagnosis and treatment of the aforementioned diseases.…”
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Sleep Disorders in Adults with Prader–Willi Syndrome: Review of the Literature and Clinical Recommendations Based on the Experience of the French Reference Centre by Pauline Dodet, Federica Sanapo, Smaranda Leu-Semenescu, Muriel Coupaye, Alice Bellicha, Isabelle Arnulf, Christine Poitou, Stefania Redolfi

“…Patients with PWS have impaired ventilatory control and altered pulmonary mechanics caused by hypotonia, respiratory muscle weakness, scoliosis and obesity. Consequently, respiratory abnormalities are frequent and, in most cases, severe, particularly during sleep. …”
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Effect of Sex, Age, and Cardiovascular Risk Factors on Aortoiliac Segment Geometry by Ádám Szőnyi, György Balázs, Balázs Bence Nyárády, Márton Philippovich, Tamás Horváth, Edit Dósa

“…<b>Methods:</b> Abdominal and pelvic CTA/MRA scans of 204 subjects (120 males; median age: 53 [IQR, 27–75] years) without AI steno-occlusive disease or scoliosis were retrospectively analyzed. The participants were enrolled consecutively, ensuring the representation of each age decade. …”
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Satisfaction following correction of spinal deformity: Cultural and regional effects on outcome by Mitsuru Yagi, MD, PhD, Ryo Mizukoshi, MD, Naruhito Fujita, MD, PhD, Haruki Funao, MD, PhD, Shigeto Ebata, MD, PhD

“…Corrective spine surgery for spinal deformities, such as adolescent idiopathic scoliosis (AIS) and adult spinal deformity (ASD), aims to enhance the quality of life by addressing physical impairments. …”
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The phenotypic spectrum of terminal 6q deletions based on a large cohort derived from social media and literature: a prominent role for DLL1 by Aafke Engwerda, Wilhelmina S. Kerstjens-Frederikse, Nicole Corsten-Janssen, Trijnie Dijkhuizen, Conny M. A. van Ravenswaaij-Arts

“…Results Using this cohort, we can identify a common terminal 6q deletion phenotype that includes microcephaly, dysplastic outer ears, hypertelorism, vision problems, abnormal eye movements, dental abnormalities, feeding problems, recurrent infections, respiratory problems, spinal cord abnormalities, abnormal vertebrae, scoliosis, joint hypermobility, brain abnormalities (ventriculomegaly/hydrocephaly, corpus callosum abnormality and cortical dysplasia), seizures, hypotonia, ataxia, torticollis, balance problems, developmental delay, sleeping problems and hyperactivity. …”
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Case report and literature review: Novel compound heterozygous FIG4 variants causing both of peripheral and central nervous system defects by Yonglin Yu, Hongwei Yin, Changli Ma, Xiaoyi Jia, Wencong Chen, Haifeng Li, Ke Wu, Ke Wu

“…At the age of 6 years, the elder brother presented with severe scoliosis and cervical kyphosis. They both had global developmental delay and a CNS involvement with cognitive deficits and swallowing problems. …”
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A Review on Cutaneous and Musculoskeletal Manifestations of CLOVES Syndrome by Öztürk Durmaz E, Demircioğlu D, Yalınay Dikmen P, Alanay Y, Alanay A, Demirkesen C, Tokat F, Karaarslan E

“…The term ‘CLOVES’ is an acronym denoting congenital lipomatous overgrowth, vascular malformations, epidermal nevi and spinal (scoliosis) and/ or skeletal anomalies. The syndrome is characterized by an admixture of overgrown tissues, derived mainly from mesoderm and neuroectoderm. …”
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Pilot study on urinary incontinence rehabilitation using non-invasive methods by Elena Costescu, Oana Păduraru, Călin Ștefan Păduraru

“…Urinary losses could be completely eliminated and the number of nighttime bath-room visits was lowered to the recommended physiological threshold (one awakening per night).Keywords: prepuberty, posture abnormalities, scoliosis, somatoscopy, physiotherapeutic assessment…”
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High-Throughput Gene and Protein Analysis Revealed the Response of Disc Cells to Vitamin D, Depending on the VDR FokI Variants by Alessandra Colombini, Paola De Luca, Davide Cangelosi, Carlotta Perucca Orfei, Enrico Ragni, Marco Viganò, Michela Malacarne, Mauro Castagnetta, Marco Brayda-Bruno, Domenico Coviello, Laura de Girolamo

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A Rare Case of Brachyolmia with Amelogenesis Imperfecta Caused by a New Pathogenic Splicing Variant in <i>LTBP3</i> by Elisabetta Flex, Valentina Imperatore, Giovanna Carpentieri, Alessandro Bruselles, Andrea Ciolfi, Simone Pizzi, Maria Giovanna Tedesco, Daniela Rogaia, Amedea Mencarelli, Giuseppe Di Cara, Alberto Verrotti, Stefania Troiani, Giuseppe Merla, Marco Tartaglia, Paolo Prontera

“…This disorder is characterized by skeletal dysplasia (e.g., platyspondyly, short trunk, scoliosis, broad ilia, elongated femoral necks with coxa valga) and severe enamel and dental anomalies. …”
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The surgical management of congenital kyphosis and kyphoscoliosis by McMaster, Michael J., Harwant Singh

“…Congenital kyphosis and kyphoscoliosis are much less common than congenital scoliosis but potentially more serious, because these curves can progress rapidly and Type I deformities can lead to spinal cord compression and paraplegia. …”
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Phenol remediation by Ipomoea aquatica forssk and toxicity evaluations on post-treatment plant extracts by Lee, Siew Yi

“…Evaluation of the toxicities of the plant extract (using 140 - 500 mg/L) on Zebrafish embryos revealed no fatal toxicities at 320 mg/L as the larvae experienced minor scoliosis and pericardium oedema while LC₅₀ BALB/c mice with oral administration of 2 000 mg/kg (acute) and 50 - 100 mg/kg/day (sub-acute) plant extracts did not record any mortality or severe toxicity symptoms. …”
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Drug-induced Fanconi syndrome in patients with kidney allograft transplantation by Zhouqi Tang, Zhouqi Tang, Tengfang Li, Tengfang Li, Helong Dai, Helong Dai, Helong Dai, Helong Dai, Chen Feng, Chen Feng, Xubiao Xie, Xubiao Xie, Fenghua Peng, Fenghua Peng, Gongbin Lan, Gongbin Lan, Shaojie Yu, Shaojie Yu, Yu Wang, Yu Wang, Chunhua Fang, Chunhua Fang, Manhua Nie, Manhua Nie, Xiaoqiong Yuan, Xiaoqiong Yuan, Xiaotian Tang, Xiaotian Tang, Xin Jiang, Xuejing Zhu, Yuxi Fan, Yuxi Fan, Jiawei Peng, Jiawei Peng, Siyu Sun, Siyu Sun, Mingda Zhong, Mingda Zhong, Hedong Zhang, Hedong Zhang, Longkai Peng, Longkai Peng

“…The above symptoms and signs were relieved after drug withdrawal, but the scoliosis was difficult to rectify. Fanconi syndrome secondary to tacrolimus has a single manifestation, increased creatinine, which can be easily confused with tacrolimus nephrotoxicity. …”
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