Non-Covid causes of acute undifferentiated febrile illness during the Covid pandemic: an etiological analysis from Uttar Pradesh, India by Vikas Kumar, Satender Saraswat, Pranay Singh, Ankur Goyal, Sanjeev Kumar, Madhav Agrawal, Himanshu Kumar

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Hemophagocytic Lymphohistiocytosis secondary to Rickettsial infection: A case report by Shriya Sharma, Aakriti Adhikari, Nirmal Ghimire, Gaurab Mainali, Sumit Kumar Yadav, Prasamsa Pudasaini, Shashank Neupane

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Scrub typus fulminating as liver failure: A rare report by Subramani Jagadeesan, Pranav Patel, Pushpendra Kushwaha, Nehal Patidar

Subjects: “…scrub typhus; fulminant hepatic failure; doxycycline; asia…”
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Genome-Wide Association Study Identifies Eight Novel Loci for Susceptibility of Scrub Typhus and Highlights Immune-Related Signaling Pathways in Its Pathogenesis by Yong-Chan Kim, Soriul Kim, Hee-Kwon Kim, Yi Lee, Chol Shin, Chang-Seop Lee, Byung-Hoon Jeong

Subjects: “…scrub typhus…”
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Expert group opinion for endemic bacterial infections in South Asia in solid organ transplant recipients - Typhoid, paratyphoid, leptospirosis, scrub typhus, and melioidosis by Vikas Deswal, Venktasubramanian Ramasubramanian, Abhyudaysingh Rana, Shyam Bihari Bansal, Sandeep Mahajan

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A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus. by Manutsanun Inthawong, Nattapon Pinthong, Areerat Thaiprakhong, Tri Wangrangsimakul, Piyanate Sunyakumthorn, Jennifer Hill, Piengchan Sonthayanon, Daniel H Paris, Susanna J Dunachie, Barbara Kronsteiner

“…We demonstrate the ability of the WBA to capture polyfunctional T cell responses in the context of acute scrub typhus infection, by measuring IFN-γ, TNF and IL-2 in CD4+ and CD8+ T cells in response to the causative agent O. tsutsugamushi (OT). …”
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Molecular Detection of Multiple Genotypes of <i>Orientia tsutsugamushi</i> Causing Scrub Typhus in Febrile Patients from Theni District, South India by Krishnamoorthy Nallan, Gopinathan Rajan, Lallitha Sivathanu, Panneer Devaraju, Balaji Thiruppathi, Ashwani Kumar, Paramasivan Rajaiah

Subjects: “…scrub typhus…”
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Comparison of indirect immunofluorescence assays for diagnosis of scrub typhus and murine typhus using venous blood and finger prick filter paper blood spots. by Phetsouvanh, R, Blacksell, S, Jenjaroen, K, Day, N, Newton, P

“…We performed indirect immunofluorescence assays (IFAs) to compare levels of IgM and IgG antibodies to Orientia tsutsugamushi and Rickettsia typhi in admission-phase serum samples and filter paper blood spots (assayed immediately and stored at 5.4 degrees C and 29 degrees C for 30 days) collected on the same day from 53 adults with suspected scrub typhus and murine typhus admitted to Mahosot Hospital Vientiane, Lao People's Democratic Republic. …”

Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of consensus leads to a lot of confusion. by Blacksell, S, Bryant, N, Paris, D, Doust, J, Sakoda, Y, Day, N

“…A review was performed to determine the evidence base for scrub typhus indirect immunofluorescence assay (IFA) methodologies and the criteria for positive results. …”

Laboratory-acquired scrub typhus and murine typhus infections: The argument for risk-based approach to biosafety requirements for Orientia tsutsugamushi and Rickettsia typhi laboratory activities by Blacksell, S, Robinson, M, Newton, P, Day, N

“…Scrub typhus LAIs were documented in 25 individuals, from 1931-2000 with 8 (32%) deaths during the pre-antibiotic era. …”

Prevalence of and factors associated with scrub typhus exposure among the hill tribe population living in high incidence areas in Thailand: a cross-sectional study by Tasak, N, Apidechkul, T, Law, ACK, Abdad, MY, Srichan, P, Perrone, C, Tanganuchitcharnchai, A, Wongsantichon, J, Blacksell, SD

“…The overall prevalence of scrub typhus exposure was 48.0%. In the multivariate model, five variables were found to be associated with scrub typhus exposure. …”

A use of 56-kDa recombinant protein of Orientia tsutsugamushi Karp serotype in serodiagnosis of scrub typhus by enzyme-linked immunosorbent assay in Thais by Chankate, P, Kalambaheti, T, Kosoltanapiwat, N, Tanganuchitcharnchai, A, Blacksell, SD, Chantratita, N, Leaungwutiwong, P

“…<p>Scrub typhus is a mite-borne disease caused by a Gram-negative obligately intracellular bacillus,&nbsp;Orientia tsutsugamushi. …”

Longitudinal comparison of bacterial pathogen seropositivity among wet market vendors in the Lao People's Democratic Republic by Nilandone Senvanpan, Vilayouth Phimolsarnnousith, Sayaphet Rattanavong, Mayfong Mayxay, Daniel Reinharz, Amanda E. Fine, Paul F. Horwood, Philippe Dussart, Stuart D. Blacksell, Mathieu Pruvot, Paul N. Newton, Matthew T. Robinson

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Vulnerability and agency in research participants' daily lives and the research encounter: A qualitative case study of participants taking part in scrub typhus research in northern Thailand. by Rachel C Greer, Nipaphan Kanthawang, Jennifer Roest, Tri Wangrangsimakul, Michael Parker, Maureen Kelley, Phaik Yeong Cheah

“…<h4>Methods</h4>A qualitative study was conducted around two scrub typhus research studies in northern Thailand. A thematic analysis was carried out on 42 semi-structured interviews with research participants, their families, researchers and key informants.…”
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Health emergency with recent surge of scrub typhus alongside other infectious diseases in India with Odisha in focus: Suggested mitigation measures and preparedness of public healthcare infrastructure by Ranjan K. Mohapatra, Snehasish Mishra, Lawrence Sena Tuglo, Venkataramana Kandi, Aroop Mohanty, Ranjit Sah

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Spatio-temporal occurrence, burden, risk factors and modelling methods for estimating scrub typhus burden from global to subnational resolutions: a systematic review protocol by Wang, Q, Sartorius, B, Philip John Day, N, James Maude, R

“…<strong>Background: <br></strong>Scrub typhus is a neglected life-threatening vector-borne disease mainly caused by the bacterium Orientia tsutsugamushi, which is occasionally transmitted to humans during feeding of larval mites. …”

Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans by Sumonwiriya, M, Paris, D, Sunyakumthorn, P, Anantatat, T, Jenjaroen, K, Chumseng, S, Im-Erbsin, R, Tanganuchitcharnchai, A, Jintaworn, S, Blacksell, S, Chowdhury, F, Kronsteiner-Dobramysl, B, Teparrukkul, P, Burke, R, Lombardini, E, Richards, A, Mason, C, Jones, J, Day, N, Dunachie, S

“…Scrub typhus is a febrile infection caused by the obligate intracellular bacterium Orientia tsutsugamushi, which causes significant morbidity and mortality across the Asia-Pacific region. …”

Vulnerability and agency in research participants' daily lives and the research encounter: a qualitative case study of participants taking part in scrub typhus research in northern Thailand by Greer, RC, Kanthawang, N, Roest, J, Wangrangsimakul, T, Parker, M, Kelley, M, Cheah, PY

“…</p> <p><strong>Methods:</strong>&nbsp;A qualitative study was conducted around two scrub typhus research studies in northern Thailand. A thematic analysis was carried out on 42 semi-structured interviews with research participants, their families, researchers and key informants.…”

Acute septic thrombophlebitis of the lower extremities due to foreign body injury and infection: a case report by Guofu Zheng, Daoxiong Xiao, Hailiang Xie, Minggui Lai, Bo Ye, Xiaochun Liu

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Detection of Orientia sp. DNA in rodents from Asia, West Africa and Europe by Jean François Cosson, Maxime Galan, Emilie Bard, Maria Razzauti, Maria Bernard, Serge Morand, Carine Brouat, Ambroise Dalecky, Khalilou Bâ, Nathalie Charbonnel, Muriel Vayssier-Taussat

Subjects: “…Scrub typhus…”
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