Dietary oleic acid contributes to the regulation of food intake through the synthesis of intestinal oleoylethanolamide by Miki Igarashi, Miki Igarashi, Miki Igarashi, Kensuke Iwasa, Tetsuhiko Hayakawa, Tsuyoshi Tsuduki, Ikuo Kimura, Ikuo Kimura, Kei Maruyama, Keisuke Yoshikawa

“…Following food consumption, OEA is synthesized from oleic acid (OA) via an N-acyl phosphatidylethanolamine-specific phospholipase D-dependent pathway in the gastroenterocytes, and OEA induces satiety by recruiting sensory fibers. Thus, we hypothesized that dietary OA is an important satiety-inducing molecule. …”
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Does Compression Sensory Axonopathy in the Proximal Tibia Contribute to Noncontact Anterior Cruciate Ligament Injury in a Causative Way?—A New Theory for the Injury Mechanism by Balázs Sonkodi, Rita Bardoni, László Hangody, Zsolt Radák, István Berkes

“…The presynaptic modulation of the primary sensory axons by the fatigued and microdamaged proprioceptive sensory fibers in the proximal tibia induces the activation of N-methyl-D-aspartate receptors in the dorsal horn of the spinal cord, through a process that could have long term relevance due to its contribution to synaptic plasticity. …”
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Median Effective Concentration of Ropivacaine for Femoral Nerve Block Maintaining Motor Function During Knee Arthroscopy in Two Age Groups by Tai YL, Peng L, Wang Y, Zhao ZJ, Li YN, Yin CP, Hou ZY, Shao DC, Zhang YH, Wang QJ

“…An ideal analgesic agent would selectively (differentially) block sensory fibers, with little or no effect on motor nerves. …”
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A Novel Collaborative Protocol for Successful Management of Penile Pain Mediated by Radiculitis of Sacral Spinal Nerve Roots From Tarlov Cysts by Irwin Goldstein, MD, Barry R. Komisaruk, PhD, Rachel S. Rubin, MD, Sue W. Goldstein, BA, Stacy Elliott, MD, Jennifer Kissee, PA, Choll W. Kim, MD, PhD

“…The neurophysiologist hypothesized the patient's pain at erection was produced by Tarlov cyst-induced neuropathic irritation of sensory fibers that course within the pelvic nerve. The spine surgeon directed a diagnostic injection of bupivacaine to the sacral nerve roots and subsequently morphine to the conus medullaris of the spinal cord. …”
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“To brain or not to brain”: evaluating the possible direct effects of the satiety factor oleoylethanolamide in the central nervous system by Adele Romano, Marzia Friuli, Barbara Eramo, Cristina Anna Gallelli, Justyna Barbara Koczwara, Elnaz Karimian Azari, Adrien Paquot, Myrtha Arnold, Wolfgang Langhans, Giulio G. Muccioli, Thomas Alexander Lutz, Silvana Gaetani

“…Then, we analyzed the pattern of OEA distribution in plasma and brain at different time points after intraperitoneal administration in addition to measuring food intake.ResultsConfirming and extending our previous findings that subdiaphragmatic vagal afferents are not necessary for the eating-inhibitory effect of exogenous OEA, our present results demonstrate that vagal sensory fibers are also not necessary for the neurochemical effects of OEA. …”
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Current understanding of the molecular mechanisms of chemotherapy-induced peripheral neuropathy by Xinyu Chen, Yumeng Gan, Ngan Pan Bennett Au, Ngan Pan Bennett Au, Ngan Pan Bennett Au, Chi Him Eddie Ma

“…Due to an ineffective blood-nerve barrier in our peripheral nervous system, exposure to some chemotherapeutic agents causes mitochondrial swelling in peripheral nerves, which lead to the opening of mitochondrial permeability transition pore and cytochrome c release resulting in degeneration of primary afferent sensory fibers. The exacerbated nociceptive signaling and pain transmission in CIPN patients is often linked the increased neuronal excitability largely due to the elevated expression of various ion channels in the dorsal root ganglion neurons. …”
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Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model by Reut Guy, Frida Grynspan, Tali Ben-Zur, Avraham Panski, Ron Lamdan, Uri Danon, David Yaffe, Daniel Offen

“…Sciatic nerve injury (SNI), which is the most common model for studying peripheral nerve injury, is characterized by damage to both motor and sensory fibers. The main goal of this study is to examine the feasibility of administration of human muscle progenitor cells (hMPCs) overexpressing neurotrophic factor (NTF) genes, known to protect peripheral neurons and enhance axon regeneration and functional recovery, to ameliorate motoric and sensory deficits in SNI mouse model. …”
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Characterization of sensory and motor dysfunction and morphological alterations in late stages of type 2 diabetic mice by Ting Tian, Ting Tian, Haofeng Li, Sensen Zhang, Maojun Yang, Maojun Yang

“…The impaired response to noxious stimuli was mainly associated with the remarkable loss of epidermal sensory fibers, particularly CGRP-positive nociceptive fibers. …”
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Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function by Dalia Rega, Mika Aiko, Nicolás Peñaranda, Amparo Urios, Juan-José Gallego, Carla Giménez-Garzó, Franc Casanova, Alessandra Fiorillo, Andrea Cabrera-Pastor, Teresa San-Miguel, Cristina Ipiens, Desamparados Escudero-García, Joan Tosca, Cristina Montón, María-Pilar Ballester, José Ballester, Luis Aparicio, María-Pilar Ríos, Lucía Durbán, Amparo Mir, Elena Kosenko, Paula Cases, Vicente Felipo, Carmina Montoliu

“…Small fibers of the autonomic nervous system and thermal sensitivity are altered early on in MHE, before large sensory fibers. Quantitative sensory testing could be used as a marker of MHE.…”
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Bilateral greater occipital nerve block for treatment of post-dural puncture headache after caesarean operations by Esra Uyar Türkyilmaz, Nuray Camgöz Eryilmaz, Nihan Aydin Güzey, Özlem Moraloğlu

“…The greater occipital nerve (GON) is formed of sensory fibers that originate in the C2 and C3 segments of the spinal cord and it is the main sensory nerve of the occipital region. …”
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Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy by Zizhen Wu, Gabor Toro, Guoying Xu, Danny Dang, Charmaine Prater, Qing Yang

“…In contrast, genetic deletion of KCNQ2 from peripheral sensory neurons in mice significantly attenuated the development of paclitaxel-induced peripheral sensory fiber degeneration and chronic pain. These findings may lead to a better understanding of the causes of PIPN and provide an impetus for developing new classes of KCNQ activators for its therapeutic treatment.…”
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Optimización de una formulación de queques (cakes) con características funcionales a partir de almidones resistentes, Sphagnum magellanicum y harina desgrasada de avellana (Gevuina... by Mario Villarroel, Carla Reyes, Julia Hazbun, Julia Karmelic

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