Successful management of a renal fungal ball in a pretermature neonate: A case report and review of literature by B V Raghunath, B C Gowrishankar, M Narendrababu, S Ramesh

“…Invasive fungal infection is common in the present day NICUs - generally manifesting as candiduria or candida sepsis. Fungal balls in the kidneys are very uncommon and most are amenable to higher antifungal agents. …”
Get full text

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017; Session "Neonatal Infectious Diseases/Immunolo... by --- Various Authors

“…PREDICTORS OF MORTALITY IN NEONATAL SEPSIS • G.I. Sarosa, R. Rahim ABS 16. DIAGNOSTIC VALUE LYMPHOCYTE TO NEUTROPHIL RATIO IN PRETERM INFANTS WITH LATE ONSET SEPSIS • S.A. …”
Get full text

Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo by Shuyuan Guan, Lingbin Sun, Xihua Wang, Xirui Huang, Tao Luo

“…Microglial activation-induced neuroinflammation is closely related to the development of sepsis-associated encephalopathy. Accumulating evidence suggests that changes in the metabolic profile of microglia is crucial for their response to inflammation. …”
Get full text

Novel rapid method for identifying and quantifying pathogenic bacteria within four hours of blood collection by Akio Miyakoshi, Hideki Niimi, Tomohiro Ueno, Masahiro Wakasugi, Yoshitsugu Higashi, Yuki Miyajima, Masashi Mori, Homare Tabata, Hiroshi Minami, Akinori Takaoka, Atsushi Hayashi, Yoshihiro Yamamoto, Isao Kitajima

“…Abstract Sepsis is life-threatening organ dysfunction and is considered a major cause of health loss. …”
Get full text

Management of postoperative enterocutaneous fistulae in children: A decade experience in a single centre by Francis A Uba, Stella C Uba, Emmanuel O Ojo

“…Background: Enterocutaneous fistula (ECF) in children poses a lot of management challenges due to sepsis, malnutrition, fluid and electrolyte deficits, which are frequent complications. …”
Get full text

Acute septic thrombophlebitis of the lower extremities due to foreign body injury and infection: a case report by Guofu Zheng, Daoxiong Xiao, Hailiang Xie, Minggui Lai, Bo Ye, Xiaochun Liu

“…Clinicians should identify the source of sepsis through a medical history and clinical examination.…”
Get full text

Case Report of Bullous Pemphigoid following Fundus Fluorescein Angiography by Goktug Demirci, Gulsen Tukenmez Demirci, Gokhan Gulkilik

“…After 1 month, the patient was transferred to the intensive care unit with sepsis secondary to urinary tract infection; he died 2 weeks later from sepsis and cardiac failure. …”
Get full text

<it>Vibrio parahemolyticus </it>septicaemia in a liver transplant patient: a case report by Fairweather Morgan G, Krishnan Sujatha, Fernando Rajeev R, Ericsson Charles D

“…We present a patient with <it>V. parahemolyticus </it>sepsis who had an orthotic liver transplant in 2007 and was on immunosuppression for chronic rejection. …”
Get full text

Exploring the mechanism of hyperpermeability following glycocalyx degradation: Beyond the glycocalyx as a structural barrier. by Kyoko Abe, Junichi Tanaka, Kenji Mishima, Takehiko Iijima

“…Pathological hyperpermeability is a morbidity involved in various systemic diseases, including sepsis. The endothelial glycocalyx layer (GCX) plays a key role in controlling vascular permeability and could be a useful therapeutic target. …”
Get full text

Gene expression profiles characterize inflammation stages in the acute lung injury in mice. by Isabelle Lesur, Julien Textoris, Béatrice Loriod, Cécile Courbon, Stéphane Garcia, Marc Leone, Catherine Nguyen

“…The outcome of a patient developing sepsis depends on two factors: the infection and the pre-existing inflammation. …”
Get full text

Impact of the implementation of Identification-Situation-Background-Assessment-Recommendation (ISBAR) tool to improve quality and safety measure in a lithotripsy and endourological... by Patricia Gadea-Company, Carmen Casal Angulo, Clara Hurtado Navarro

“…The reduction in the main postoperative complication (sepsis) explained the lower hospital stay for group B. …”
Get full text

Inhibition of Cerebral High-Mobility Group Box 1 Protein Attenuates Multiple Organ Damage and Improves T Cell-Mediated Immunity in Septic Rats by Chao Ren, Xiu-hua Li, Yao Wu, Ning Dong, Ya-lin Tong, Yong-ming Yao

“…Sepsis remains one of the leading causes of mortality in intensive care units, but there is a shortage of effective treatments. …”
Get full text

Review of Infant and Child Death in a Tertiary Care Teaching Institute in Surat by Rajiv Kumar Prasad, Rachana Prasad, Vibhuti Vaghela, Chetan B Chovatiya

“…Conclusions: Immediate cause of death was sepsis, HMD, MAS and birth asphyxia. Underlying cause was extreme prematurity, prematurity, sepsis and birth asphyxia. …”
Get full text

Acute Respiratory Distress Syndrome by Arief Bakhtiar, Rena Arusita Maranatha

“…Cases of ARDS related to pulmonary sepsis, such as pneumonia, inhalational trauma, and pulmonary contusions are as much as 46% or non-pulmonary sepsis as much as 33%. …”
Get full text

Enrichment of HIV-1 subtype AD recombinants in a Ugandan cohort of severely septic patients. by Najah I Doka, Shevin T Jacob, Patrick Banura, Christopher C Moore, David Meya, Harriet Mayanja-Kizza, Steven J Reynolds, W Michael Scheld, Wen Yuan

“…Given the differences in HIV-1 disease progression based on subtype, we examined HIV-1 subtype distribution and disease outcomes among hospitalized patients with severe sepsis.Patients with severe sepsis were enrolled at two hospitals in Uganda. …”
Get full text

The association of mannose-binding lectin 2 polymorphisms with outcome in very low birth weight infants. by Annika Hartz, Julia Pagel, Alexander Humberg, Michael Preuss, Lena Schreiter, Jan Rupp, Julia Figge, Christian M Karsten, Peter Nürnberg, Egbert Herting, Wolfgang Göpel, Christoph Härtel, German Neonatal Network (GNN)

“…Primary outcome was the effect of genotype-based MBL2 levels on blood-culture proven and clinical sepsis during primary stay in hospital. We also evaluated burden of infection within 24 months after discharge.We found no association between MBL levels and sepsis risk in the whole cohort. …”
Get full text

Isolation rate and clinical significance of uropathogens in positive urine cultures of hemodialysis patients by Katerina G Oikonomou, Adib Alhaddad

“…Identification of E. coli as the involved uropathogen was associated neither with a growth of ≥105 CFU/ml, presence of fever, sepsis, urinary catheter use nor with higher antimicrobial resistance. …”
Get full text

Spatial adjustment of bioenergetics, a possible determinant of contractile adaptation and development of contractile failure by Marten Szibor, Marten Szibor, Marie Mühlon, Torsten Doenst, Jaakko L. O. Pohjoismäki

Get full text

Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

“…The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung injury, as indicated by alleviated lung pathological changes and infiltration of proteins and leukocytes. …”
Get full text

Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism. by Zhongshuang Hu, Taisuke Murakami, Kaori Suzuki, Hiroshi Tamura, Kyoko Kuwahara-Arai, Toshiaki Iba, Isao Nagaoka

“…Thus, the present finding may provide a novel insight into the modulation of sepsis utilizing LL-37 with a dual action on the LPS binding and P2X7 activation.…”
Get full text