Serine and arginine rich splicing factor 1: a potential target for neuroprotection and other diseases by Ana M Sandoval-Castellanos, Anushka Bhargava, Min Zhao, Jun Xu, Ke Ning

“…Serine and arginine rich splicing factor 1, part of the arginine/serine-rich splicing factor protein family, can either activate or inhibit the splicing of mRNAs, depending on the phosphorylation status of the protein and its interaction partners. …”
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Physicochemical Properties and Elimination of the Activity of Anti-Nutritional Serine Protease Inhibitors from Mulberry Leaves by Zhuxing Luo, Jinhong Yang, Jie Zhang, Gang Meng, Qingjun Lu, Xi Yang, Ping Zhao, Youshan Li

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Heat Capacities of L-Cysteine, L-Serine, L-Threonine, L-Lysine, and L-Methionine by Václav Pokorný, Vojtěch Štejfa, Jakub Havlín, Michal Fulem, Květoslav Růžička

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The Critical Role Played by Mitochondrial MITF Serine 73 Phosphorylation in Immunologically Activated Mast Cells by Lakshmi Bhargavi Paruchuru, Sharmila Govindaraj, Ehud Razin

“…Thus, the present research findings highlight the prominence of mitochondrial MITF Serine 73 phosphorylation in immunologically activated mast cells.…”
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Doxycycline Interferes with Zika Virus Serine Protease and Inhibits Virus Replication in Human Skin Fibroblasts by Teow Chong Teoh, Sawsam J. Al-Harbi, Ammar Yasir Abdulrahman, Hussin A. Rothan

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Juvenile-onset PSAT1-related neuropathy: A milder phenotype of serine deficiency disorder by Yu Shen, Yun Peng, Yun Peng, Pengcheng Huang, Yilei Zheng, Shumeng Li, Kaiyan Jiang, Meihong Zhou, Jianwen Deng, Min Zhu, Min Zhu, Daojun Hong, Daojun Hong

Subjects: “…serine deficiency disorder…”
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Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function by Tao, Jifang, Hu, Keping, Chang, Qiang, Wu, Hao, Sherman, Nicholas E., Martinowich, Keri, Klose, Robert J., Schanen, Carolyn, Jaenisch, Rudolf, Wang, Weidong, Sun, Yi Eve

“…Although neuronal activity-induced phosphorylation of MeCP2 at serine 421 (S421) has been reported, the full spectrum of MeCP2 phosphorylation together with the in vivo function of such modifications are yet to be revealed. …”
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Epigenetic landscapes of De Novo Serine synthesis pathway in natural killer/T cell lymphoma (NKTL) by Zhang, Jiexin

“…The ISR is mediated by phosphorylated eIF2-alpha (eIF2α) and activating transcription factor 4 (ATF4), with the latter transactivating target genes in numerous pathways, including that of De Novo Serine Synthesis (DNSS). This project focuses on elucidating the mechanism of this pathway in NKTL.…”
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The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases. by Hoa, N, Brannigan, J, Cutting, S

“…We have defined the putative catalytic domain of the SpoIVB serine peptidase as a 160-amino-acid residue segment at the carboxyl terminus of the protein. …”

Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression by Egloff, S, O'Reilly, D, Chapman, R, Taylor, A, Tanzhaus, K, Pitts, L, Eick, D, Murphy, S

“…We show that mutation of serine-7 to alanine causes a specific defect in snRNA gene expression. …”

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase by Harrison, PJ, Gable, K, Somashekarappa, N, Kelly, V, Clarke, DJ, Naismith, JH, Dunn, TM, Campopiano, DJ

“…Isotopically-labelled L-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltransferase (SPT) as well as labelling downstream cellular metabolites. …”

Immunisation against a serine protease inhibitor reduces intensity of Plasmodium berghei infection in mosquitoes. by Williams, A, Zakutansky, SE, Miura, K, Dicks, MD, Churcher, T, Jewell, K, Vaughan, A, Turner, A, Kapulu, M, Michel, K, Long, C, Sinden, R, Hill, A, Draper, S, Biswas, S

“…This immune clearance is controlled by a number of regulatory molecules including serine protease inhibitors (serpins). To determine whether such molecules could represent a novel target for a malaria transmission-blocking vaccine, we vaccinated mice with Anopheles gambiae serpin-2. …”

Investigation on the molecular mechanism of 2OG-oxygenases and serine β-lactamases through computational chemistry by Choi, H

“…Chapter 2 describes QM and MD calculations to investigate recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition. β-Lactams inhibit penicillin-binding proteins (PBPs) and serine β-lactamases by acylation of a nucleophilic active site serine. …”

Polymer supported oxazolidin-2-ones derived from L-serine - a cautionary tale by Bew, S, Bull, S, Davies, S

“…The capacity of N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O acyl transfer makes these serine derived chiral auxiliaries unsuitable for attachment to polymers. …”

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. by Tao, J, Hu, K, Chang, Q, Wu, H, Sherman, N, Martinowich, K, Klose, R, Schanen, C, Jaenisch, R, Wang, W, Sun, Y

“…Although neuronal activity-induced phosphorylation of MeCP2 at serine 421 (S421) has been reported, the full spectrum of MeCP2 phosphorylation together with the in vivo function of such modifications are yet to be revealed. …”

Construction of dna vaccine expressing serine repeat antigen (sera) malarial epitope of plasmodium falciparijm by Nadia, Sedi

“…In order to resolve this problem an asexual blood stage antigen of P. falciparum, serine repeat antigen (SERA) is reported to be one of the promising vaccine candidates. …”
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Aedes aegypti CLIPB9 activates prophenoloxidase-3 in the presence of CLIPA14 after fungal infection by Yannan Ji, Yannan Ji, Tengfei Lu, Tengfei Lu, Zhen Zou, Zhen Zou, Yanhong Wang, Yanhong Wang

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AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth by Hye Jin Yun, Min Li, Dong Guo, So Mi Jeon, Su Hwan Park, Je Sun Lim, Su Bin Lee, Rui Liu, Linyong Du, Seok-Ho Kim, Tae Hwan Shin, Seong-il Eyun, Yun-Yong Park, Zhimin Lu, Jong-Ho Lee

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Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase by Giulia Murtas, Giorgia Letizia Marcone, Alessio Peracchi, Erika Zangelmi, Loredano Pollegioni

Subjects: “…L-serine…”
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Phosphorylation of Calpastatin Negatively Regulates the Activity of Calpain by Yuqiang Bai, Chengli Hou, Caiyan Huang, Fei Fang, Yu Dong, Xin Li, Dequan Zhang

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