Structure and activity of factor D̄ of the alternative pathway of human complement by Schneider, D, Johnson, Diana Margaret Ashley

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Regional contributions of D-serine to Alzheimer’s disease pathology in male AppNL–G–F/NL–G–F mice by Xiance Ni, Xiance Ni, Ran Inoue, Ran Inoue, Yi Wu, Yi Wu, Tomoyuki Yoshida, Tomoyuki Yoshida, Keisuke Yaku, Takashi Nakagawa, Takashi Nakagawa, Takashi Saito, Takashi Saito, Takaomi C. Saido, Keizo Takao, Keizo Takao, Keizo Takao, Hisashi Mori, Hisashi Mori, Hisashi Mori

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Adaptation of <i>Helicoverpa armigera</i> to Soybean Peptidase Inhibitors Is Associated with the Transgenerational Upregulation of Serine Peptidases by Pedro A. Velasquez-Vasconez, Benjamin J. Hunt, Renata O. Dias, Thaís P. Souza, Chris Bass, Marcio C. Silva-Filho

“…Using transcriptome profiling, we show that the adaptation of <i>Helicoverpa armigera</i> larvae to soybean peptidase inhibitors (SPIs) is associated with large-scale gene expression changes including the upregulation of genes encoding serine peptidases in the digestive system. Furthermore, approximately 60% of the gene expression changes induced by SPIs persisted in the next generation of larvae fed on SPI-free diets including genes encoding regulatory, oxidoreductase, and protease functions. …”
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A Mycobacterium avium subsp. paratuberculosis predicted serine protease is associated with acid stress and intraphagosomal survival by Abirami Kugadas, Elise A Lamont, John P Bannantine, Fernanda Miyagaki Shoyama, Evan Brenner, Harish Kumar Janagama, Srinand Sreevastan

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SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases by Fabrice Gonnot, Laura Boulogne, Camille Brun, Maya Dia, Yves Gouriou, Gabriel Bidaux, Christophe Chouabe, Claire Crola Da Silva, Sylvie Ducreux, Bruno Pillot, Andrea Kaczmarczyk, Christelle Leon, Stephanie Chanon, Coralie Perret, Franck Sciandra, Tanushri Dargar, Vincent Gache, Fadi Farhat, Laurent Sebbag, Thomas Bochaton, Helene Thibault, Michel Ovize, Melanie Paillard, Ludovic Gomez

“…Indeed, the phosphorylation level of SERCA2 at serine 663 is increased in ischemic hearts of patients and mouse. …”
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Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases by Alba Ramos-Llorca, Lisse Decraecker, Valérie M. Y. Cacheux, Irena Zeiburlina, Michelle De bruyn, Louise Battut, Carlos Moreno-Cinos, Davide Ceradini, Eric Espinosa, Gilles Dietrich, Maya Berg, Ingrid De Meester, Pieter Van Der Veken, Guy Boeckxstaens, Anne-Marie Lambeir, Alexandre Denadai-Souza, Koen Augustyns

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Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation by Florentin Huguet, Ezgi Gokhan, Helen A. Foster, Hasnat A. Amin, Paola Vagnarelli

“…One of the mitotic phosphosites in lamin A responsible for its dynamic behaviour is serine 22 (S22) which is de-phosphorylated during mitotic exit. …”
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TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer by Semi Kim

“…Over the past two decades, a novel subfamily of serine proteases called type II transmembrane serine proteases (TTSPs) has been identified. …”
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Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms by Nessrin Alomran, Patricia Blundell, Jaffer Alsolaiss, Edouard Crittenden, Stuart Ainsworth, Charlotte A. Dawson, Rebecca J. Edge, Steven R. Hall, Robert A. Harrison, Mark C. Wilkinson, Stefanie K. Menzies, Nicholas R. Casewell

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Extracellular serine-proteinases isolated from Streptomyces alboniger: Partial characterization and effect of aprotinin on cellular structure by Lopes Andréa, Coelho Rosalie RR, Meirelles Maria Nazareth L, Branquinha Marta Helena, Vermelho Alane Beatriz

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Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells by Sam Blanchett, Yves Dondelinger, Yves Dondelinger, Alessandro Barbarulo, Mathieu J. M. Bertrand, Mathieu J. M. Bertrand, Benedict Seddon

“…More recently, IKK has also been shown to repress RIPK1 dependent extrinsic cell death pathways by directly phosphorylating RIPK1 at serine 25. In T cells, IKK expression is essential for normal development in the thymus, by promoting survival of thymocytes independently of NF-κB activation. …”
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Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer by Fatma H. Al-Awadhi, Lilibeth A. Salvador, Brian K. Law, Valerie J. Paul, Hendrik Luesch

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The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung Diseases by Gillian A. Kelly-Robinson, James A. Reihill, Fionnuala T. Lundy, Lorcan P. McGarvey, John C. Lockhart, Gary J. Litherland, Keith D. Thornbury, S. Lorraine Martin

Subjects: “…serine protease…”
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Inferring selection in the <it>Anopheles gambiae </it>species complex: an example from immune-related serine protease inhibitors by Little Tom J, Welch John J, Obbard Darren J

“…</p> <p>Methods</p> <p>Three serine protease inhibitors have previously been identified as candidate immune system genes mediating mosquito-Plasmodium interaction, and serine protease inhibitors have been identified as hot-spots of adaptive evolution in other taxa. …”
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Serine/Threonine Phosphatases in LTP: Two B or Not to Be the Protein Synthesis Blocker-Induced Impairment of Early Phase by Alexander V. Maltsev, Natalia V. Bal, Pavel M. Balaban

“…Dephosphorylation of target proteins at serine/threonine residues is one of the most crucial mechanisms regulating their activity and, consequently, the cellular functions. …”
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An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells. by Jessica Basso, Jimin Zhang, Daniel Lasala, Sasha J Rose, Kuan-Ju Chen, David Cipolla

“…<h4>Purpose</h4>Neutrophil serine proteases (NSPs) are implicated in numerous inflammatory diseases. …”
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L-Serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen by Jianxia Zhou, Dingyun Feng, Xia Li, Yuetao Chen, Min Zhang, Wenbin Wu, Jiaxin Zhu, Hui Li, Xuanxian Peng, Tiantuo Zhang

“…Our analysis revealed the effect of L-serine on reducing the virulence of A.baumannii. This discovery suggests that targeting L-serine could be a promising strategy for the treatment or adjunctive treatment of A. baumannii infections. …”
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Catalytic activity of a novel serine/threonine protein phosphatase PP5 from Leishmania major by Norris-Mullins Brianna, Vacchina Paola, Morales Miguel A.

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Nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi (TcNMNAT): a cytosol protein target for serine kinases by Diana Milena Sánchez-Lancheros, Luis Fernando Ospina-Giraldo, María Helena Ramírez-Hernández

“…Possible phosphorylation events were experimentally analysed by western blot, highlighting TcNMNAT as a potential target for serine kinases.…”
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Artificial intelligence-driven new drug discovery targeting serine/threonine kinase 33 for cancer treatment by Na Ly Tran, Hyerim Kim, Cheol-Hee Shin, Eun Ko, Seung Ja Oh

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