Connexin 43 dephosphorylation at serine 282 induces spontaneous arrhythmia and increases susceptibility to ischemia/reperfusion injury by Lulin Wu, Tianhui Jiang, Zhiping Fu, Luqi Wang, Hongjie You, Jingyi Xue, Dali Luo

Get full text

Expression of Serine Biosynthesis Pathway Genes in Breast Muscles of Iranian Native Turkeys with Divergent Feed Efficiency by Zahra Pezeshkian, Seyed Ziaeddin Mirhoseini, Shahrokh Ghovvati, Esmaeil Ebrahimie

Subjects: Get full text

A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. by Tasia M Pyburn, Barbara A Bensing, Yan Q Xiong, Bruce J Melancon, Thomas M Tomasiak, Nicholas J Ward, Victoria Yankovskaya, Kevin M Oliver, Gary Cecchini, Gary A Sulikowski, Matthew J Tyska, Paul M Sullam, T M Iverson

“…GspB is a serine-rich repeat (SRR) adhesin of Streptococcus gordonii that mediates binding of this organism to human platelets via its interaction with sialyl-T antigen on the receptor GPIbα. …”
Get full text

In order to lower the antinutritional activity of serine protease inhibitors, we need to understand their role in seed development by Juan Vorster, Willem van der Westhuizen, Gedion du Plessis, Diana Marais, Francesca Sparvoli, Eleonora Cominelli, Emanuela Camilli, Marika Ferrari, Cinzia Le Donne, Stefania Marconi, Silvia Lisciani, Alessia Losa, Tea Sala, Karl Kunert

Subjects: “…serine proteases…”
Get full text

Comprehensive study of serine/arginine-rich (SR) gene family in rice: characterization, evolution and expression analysis by Rui Gao, Yingying Lu, Nan Wu, Hui Liu, Xiaoli Jin

“…As important regulators of alternative splicing (AS) events, serine/arginine (SR)-rich proteins play indispensable roles in the growth and development of organisms. …”
Get full text

Effects of L-serine on oxidative stress indices and histopathological changes of pancreas in streptozotocin-induced diabetic mice by Mahshad Sheikhi Narani, Akram Vatannejad, Asma Kheirollahi, Farzaneh Ershad Langeroudi, Sara Shokrpoor, Samira Alizadeh, Asie Sadeghi

Subjects: Get full text

Pharmacokinetics of Nafamostat, a Potent Serine Protease Inhibitor, by a Novel LC-MS/MS Analysis by Hyeon Seok Oh, Taehyung Kim, Dong-Hyeon Gu, Tae Suk Lee, Tae Hwan Kim, Soyoung Shin, Beom Soo Shin

“…Nafamostat, a synthetic serine protease inhibitor, has been used for the treatment of inflammatory diseases such as pancreatitis. …”
Get full text

Correction: The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation

Get full text

YY2/PHGDH axis suppresses tumorigenesis by inhibiting tumor cell de novo serine biosynthesis by Juan Li, Xinxin Luo, Mankun Wei, Zhuolin Li, Yanjun Li, Hezhao Zhao, Makoto Miyagishi, Vivi Kasim, Shourong Wu

Subjects: Get full text

EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation by Haoqiang Jiang, Haoqiang Jiang, Shipeng Shang, Yutong Sha, Lin Zhang, Ningning He, Lei Li, Lei Li

“…For example, the characteristics of serine phosphorylation (pS) and serine ADP-ribosylation (SADPr) have been investigated, whereas those of their in situ crosstalks (pSADPr) are unknown. …”
Get full text

Serine 31 Phosphorylation-Driven Regulation of AGPase Activity: Potential Implications for Enhanced Starch Yields in Crops by Guowu Yu, Yuewei Mou, Noman Shoaib, Xuewu He, Lun Liu, Runze Di, Nishbah Mughal, Na Zhang, Yubi Huang

“…Subsequently, to ascertain the impact of Sh2 phosphorylation on AGPase, we carried out site-directed mutations creating Sh2-S31A (serine residue replaced with alanine) to mimic dephosphorylation and Sh2-S31D (serine residue replaced with aspartic acid) or Sh2-S31E (serine residue replaced with glutamic acid) to mimic phosphorylation. …”
Get full text

Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism by Angela Pelligra, Jessica Mrugala, Kerstin Griess, Philip Kirschner, Oliver Nortmann, Barbara Bartosinska, Andrea Köster, Natalia I. Krupenko, Dominik Gebel, Philipp Westhoff, Bodo Steckel, Daniel Eberhard, Diran Herebian, Bengt-Frederik Belgardt, Jürgen Schrader, Andreas P.M. Weber, Sergey A. Krupenko, Eckhard Lammert

“…Bulk RNA sequencing of islets shows increased expression of genes for serine-linked mitochondrial one-carbon metabolism (OCM) after chronic, but not acute, stimulation. …”
Get full text

Systematic functional analysis and potential application of a serine protease from cold-adapted Planococcus bacterium by Weijun Leng, Xiaoyun Wu, Xianghui Qi, Hongying Liu, Li Yuan, Ruichang Gao

“…In this study, a gene encoding serine protease (PmSpr288) from cold-adapted bacterium, namely Planococcus maritimus XJ11, was cloned and overexpressed in Escherichia coli BL21 (DE3). …”
Get full text

The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol by Flores Rhonda, Chen Ding, Gong Siqi, Lei Lei, Wu Xiang, Zhong Guangming

Subjects: Get full text

Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors by Osamu Sano, Ken‐ichi Kazetani, Ryutaro Adachi, Osamu Kurasawa, Tomohiro Kawamoto, Hidehisa Iwata

Subjects: Get full text

Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment by Morena Miciaccia, Francesca Rizzo, Antonella Centonze, Gianfranco Cavallaro, Marialessandra Contino, Domenico Armenise, Olga Maria Baldelli, Roberta Solidoro, Savina Ferorelli, Pasquale Scarcia, Gennaro Agrimi, Veronica Zingales, Elisa Cimetta, Simone Ronsisvalle, Federica Maria Sipala, Paola Loguercio Polosa, Cosimo Gianluca Fortuna, Maria Grazia Perrone, Antonio Scilimati

“…A single-crystal X-ray analysis of the complex of the human mitochondrial caseinolytic serine protease type C (<i>h</i>ClpP) and ONC201 (PDB ID: 6DL7) allowed <i>h</i>ClpP to be identified as its main target. …”
Get full text

Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2 by Qi Tan, Jiewen Fu, Zhiying Liu, Haoyue Deng, Lianmei Zhang, Jiayue He, Xiaotao Li, Junjiang Fu, Xiangxiang Pan, Peifang Wei

Get full text

Serine protease CrKP43 interacts with MAPK and regulates fungal development and mycoparasitism in Clonostachys chloroleuca by Binna Lv, Xue Zhao, Yan Guo, Shidong Li, Manhong Sun

Subjects: Get full text

The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study by Hung N. Luu, Pedram Paragomi, Renwei Wang, Joyce Y. Huang, Jennifer Adams-Haduch, Øivind Midttun, Arve Ulvik, Tin C. Nguyen, Randall E. Brand, Yutang Gao, Per Magne Ueland, Jian-Min Yuan

Subjects: Get full text

Purification and characterization of thiol dependent, oxidation-stable serine alkaline protease from thermophilic Bacillus sp. by Aysha Kamran, Haneef Ur Rehman, Shah Ali Ul Qader, Abdul Hameed Baloch, Mustafa Kamal

Subjects: “…Thermophilic serine protease…”
Get full text