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Serine ADP-ribosylation reversal by the hydrolase ARH3
Published 2017-06-01“…We recently discovered a new form of ADPr that is attached to serine residues in target proteins (Ser-ADPr) and showed that this PTM is specifically made by PARP1/HPF1 and PARP2/HPF1 complexes. …”
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22
The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies
Published 2018-07-01Subjects: Get full text
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23
Separation and detection of D-/L-serine by conventional HPLC
Published 2022-01-01Subjects: Get full text
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24
Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage
Published 2021-02-01Subjects: “…serine proteases…”
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25
Commentary: Fungal lifestyle reflected in serine protease repertoire
Published 2018-03-01Get full text
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26
Towards understandings of serine/arginine-rich splicing factors
Published 2023-08-01“…Serine/arginine-rich splicing factors (SRSFs) refer to twelve RNA-binding proteins which regulate splice site recognition and spliceosome assembly during precursor messenger RNA splicing. …”
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The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
Published 2020-03-01Subjects: “…serine…”
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28
Excitatory and inhibitory D-serine binding to the NMDA receptor
Published 2022-10-01“…Surprisingly, we observed D-serine binding to both GluN1 and GluN2A LBDs, suggesting that D-serine competes with glutamate for binding to GluN2A. …”
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D-Serine reduces the expression of the cytopathic genotoxin colibactin
Published 2023-03-01“…Whilst several D-amino acids exhibited the abil-ity to inhibit expression of clbB, D-Serine exerted the strongest repressing ac-tivity (>3.8-fold) and thus, we focussed additional experiments on D-Serine. …”
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Serine ADP-ribosylation reversal by the hydrolase ARH3
Published 2017“…We recently discovered a new form of ADPr that is attached to serine residues in target proteins (Ser-ADPr) and showed that this PTM is specifically made by PARP1/HPF1 and PARP2/HPF1 complexes. …”
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Investigating the role of serine-ADP-ribosylation in human cells
Published 2022“…</p> <p>Here, we assessed the abundance of serine-ADPr in human cells, and performed the validation of several serine-ADPr substrates, including histones. …”
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Structural basis for the interaction of lactivicins with serine beta-lactamases.
Published 2010“…Lactivicin (LTV) is a natural non-beta-lactam antibiotic that inhibits penicillin-binding proteins and serine beta-lactamases. A crystal structure of a BS3-LTV complex reveals that, as for its reaction with PBPs, LTV reacts with the nucleophilic serine and that cycloserine and lactone rings of LTV are opened. …”
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Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
Published 1999“…Although originally discovered as inhibitors of pencillin-binding proteins, beta-lactams have more recently found utility as serine protease inhibitors. Indeed through their ability to react irreversibly with nucleophilic serine residues they have proved extraordinarily successful as enzyme inhibitors. …”
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34
Impact of aspartate and serine on mouse embryo development in vitro
Published 2014Get full text
Conference or Workshop Item -
35
Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi
Published 2013-09-01“…Thus, characterising serine proteinase inhibitors may provide new targets and strategies to prevent transmission of Leishmania.…”
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Novel inhibitors and activity-based probes targeting serine proteases
Published 2022-09-01Subjects: “…serine protease…”
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Serine is the major residue for ADP-ribosylation upon DNA damage
Published 2018-02-01“…Furthermore, we describe a method for site-specific validation of serine ADP-ribosylated substrates in cells. Our study establishes serine as the primary form of ADPr in DNA damage signalling.…”
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Changes of lysosome by L-serine in rotenone-treated hippocampal neurons
Published 2023-01-01Subjects: “…L-serine…”
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39
Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine
Published 2022-12-01Subjects: Get full text
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40
Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases
Published 2022-04-01Subjects: “…serine proteases…”
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Article