Showing 21 - 40 results of 7,605 for search '"serine"', query time: 0.14s Refine Results
  1. 21

    Serine ADP-ribosylation reversal by the hydrolase ARH3 by Pietro Fontana, Juan José Bonfiglio, Luca Palazzo, Edward Bartlett, Ivan Matic, Ivan Ahel

    Published 2017-06-01
    “…We recently discovered a new form of ADPr that is attached to serine residues in target proteins (Ser-ADPr) and showed that this PTM is specifically made by PARP1/HPF1 and PARP2/HPF1 complexes. …”
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    Article
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    Towards understandings of serine/arginine-rich splicing factors by Dianyang Li, Wenying Yu, Maode Lai

    Published 2023-08-01
    “…Serine/arginine-rich splicing factors (SRSFs) refer to twelve RNA-binding proteins which regulate splice site recognition and spliceosome assembly during precursor messenger RNA splicing. …”
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    Article
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    Excitatory and inhibitory D-serine binding to the NMDA receptor by Remy A Yovanno, Tsung Han Chou, Sarah J Brantley, Hiro Furukawa, Albert Y Lau

    Published 2022-10-01
    “…Surprisingly, we observed D-serine binding to both GluN1 and GluN2A LBDs, suggesting that D-serine competes with glutamate for binding to GluN2A. …”
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    Article
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    D-Serine reduces the expression of the cytopathic genotoxin colibactin by Jennifer C. Hallam, Sofia Sandalli, Iris Floria, Natasha C. A. Turner, Min Tang-Fichaux, Eric Oswald, Nicky O’Boyle, Andrew J. Roe

    Published 2023-03-01
    “…Whilst several D-amino acids exhibited the abil-ity to inhibit expression of clbB, D-Serine exerted the strongest repressing ac-tivity (>3.8-fold) and thus, we focussed additional experiments on D-Serine. …”
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    Article
  10. 30

    Serine ADP-ribosylation reversal by the hydrolase ARH3 by Fontana, P, Bonfiglio, J, Palazzo, L, Bartlett, E, Matic, I, Ahel, I

    Published 2017
    “…We recently discovered a new form of ADPr that is attached to serine residues in target proteins (Ser-ADPr) and showed that this PTM is specifically made by PARP1/HPF1 and PARP2/HPF1 complexes. …”
    Journal article
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    Investigating the role of serine-ADP-ribosylation in human cells by Prokhorova, E

    Published 2022
    “…</p> <p>Here, we assessed the abundance of serine-ADPr in human cells, and performed the validation of several serine-ADPr substrates, including histones. …”
    Thesis
  12. 32

    Structural basis for the interaction of lactivicins with serine beta-lactamases. by Brown, T, Charlier, P, Herman, R, Schofield, C, Sauvage, E

    Published 2010
    “…Lactivicin (LTV) is a natural non-beta-lactam antibiotic that inhibits penicillin-binding proteins and serine beta-lactamases. A crystal structure of a BS3-LTV complex reveals that, as for its reaction with PBPs, LTV reacts with the nucleophilic serine and that cycloserine and lactone rings of LTV are opened. …”
    Journal article
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    Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. by Wilmouth, R, Kassamally, S, Westwood, N, Sheppard, R, Claridge, T, Aplin, RT, Wright, P, Pritchard, G, Schofield, C

    Published 1999
    “…Although originally discovered as inhibitors of pencillin-binding proteins, beta-lactams have more recently found utility as serine protease inhibitors. Indeed through their ability to react irreversibly with nucleophilic serine residues they have proved extraordinarily successful as enzyme inhibitors. …”
    Journal article
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    Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi by Leah Theresa Sigle, Marcelo Ramalho-Ortigao

    Published 2013-09-01
    “…Thus, characterising serine proteinase inhibitors may provide new targets and strategies to prevent transmission of Leishmania.…”
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    Article
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    Serine is the major residue for ADP-ribosylation upon DNA damage by Luca Palazzo, Orsolya Leidecker, Evgeniia Prokhorova, Helen Dauben, Ivan Matic, Ivan Ahel

    Published 2018-02-01
    “…Furthermore, we describe a method for site-specific validation of serine ADP-ribosylated substrates in cells. Our study establishes serine as the primary form of ADPr in DNA damage signalling.…”
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    Article
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