Competitive Activity-Based Protein Profiling Identifies Aza-β-Lactams as a Versatile Chemotype for Serine Hydrolase Inhibition by Zuhl, Andrea M., Mohr, Justin T., Bachovchin, Daniel A., Niessen, Sherry, Hsu, Ku-Lung, Berlin, Jacob M., Dochnahl, Maximilian, Fu, Gregory C., Cravatt, Benjamin F., Lopez-Alberca, Maria P.

“…Serine hydrolases are one of the largest and most diverse enzyme classes in Nature. …”
Get full text

Serine/threonine-protein kinase PFTAIRE-1 (PFTK1) modulates differentiation and proliferation of Oligodendrocyte Precursor Cells (OPCs). by Tan, Hsien Yeow.

Get full text

Identification of a novel mRNA species of the LKB1/STK11 Peutz-Jeghers serine/threonine kinase. by Churchman, M, Dowling, B, Tomlinson, I

“…The translated region of LKB1/STK11 (1302bp) codes for a serine/threonine kinase of otherwise unknown function. …”

Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome. by Xu, Z, Thomas, L, Davies, B, Chalmers, R, Smith, M, Brown, W

“…BACKGROUND: Phage-encoded serine integrases, such as φC31 integrase, are widely used for genome engineering. …”

Developmental expression of a tandemly repeated, glycine- and serine-rich spore wall protein in the microsporidian pathogen Encephalitozoon cuniculi. by Bohne, W, Ferguson, D, Kohler, K, Gross, U

“…The carboxy-terminal region consists of five tandemly arranged glycine- and serine-rich repetitive elements. SWP1 is a single-copy gene that is also present in the genomes of Encephalitozoon intestinalis and Encephalitozoon hellem as demonstrated by Southern analysis. …”

Interleukin-6 induces translocation of the adapter protein GAB1 by MAPK-dependent phosphorylation of GAB1 on serine 552 by Wolf, A, Eulenfeld, R, Feller, S, Schaper, F

Cloning, expression and characterization of serine/threonine protein phosphatase and kinases of Mycobacterium bovis BCG (Pasteur 1173P2) by Ainol Azifa Mohd Faik

“…In this study, three genes with sequence homology to those encoding serine/threonine kinases (pknl, pknK) and serine/threonine phosphatase (ppp) in Mycobacterium tuberculosis HxJ?…”
Get full text
Get full text

Optimization of the conditions for extraction of serine protease from kesinai plant (Streblus asper) leaves using response surface methodology. by Mehrnoush, Amid, Mustafa, Shuhaimi, Sarker, Zaidul Islam, Abd. Manap, Mohd. Yazid

“…Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of serine protease from kesinai (Streblus asper) leaves. …”
Get full text

Exploring the chemical space around N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide, a hit compound with serine acetyltransferase (SAT) inhibitory properties by Marialaura Pavone, Samanta Raboni, Marialaura Marchetti, Giannamaria Annunziato, Stefano Bettati, Bianca Papotti, Cinzia Marchi, Emanuele Carosati, Marco Pieroni, Barbara Campanini, Gabriele Costantino

Subjects: Get full text

Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoprotiens / by Tew, David G.

Mutations at the Serine Hydroxymethyltransferase Impact Its Interaction with a Soluble NSF Attachment Protein and a Pathogenesis-Related Protein in Soybean by Naoufal Lakhssassi, Sarbottam Piya, Dounya Knizia, Abdelhalim El Baze, Mallory A. Cullen, Jonas Meksem, Aicha Lakhssassi, Tarek Hewezi, Khalid Meksem

“…<i>Rhg4-a</i> encodes a serine hydroxymethyltransferase (GmSHMT08) and <i>rhg1-a</i> encodes a soluble NSF attachment protein (GmSNAP18). …”
Get full text

Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes by Sowmiya Palani, Yuka Machida, Julia R. Alvey, Vandana Mishra, Allison L. Welter, Gaofeng Cui, Benoît Bragantini , Maria Victoria Botuyan, Anh T. Q. Cong, Georges Mer, Matthew J. Schellenberg, Yuichi J. Machida

“…Abstract FAM111A, a serine protease, plays roles in DNA replication and antiviral defense. …”
Get full text

The Procoagulant Snake Venom Serine Protease Potentially Having a Dual, Blood Coagulation Factor V and X-Activating Activity by Zorica Latinović, Adrijana Leonardi, Cho Yeow Koh, R. Manjunatha Kini, Alenka Trampuš Bakija, Jože Pungerčar, Igor Križaj

Subjects: Get full text

The spleen as a possible source of serine protease inhibitors and migrating monocytes required for liver regeneration after 70% resection in mice by Andrey Elchaninov, Andrey Elchaninov, Polina Vishnyakova, Polina Vishnyakova, Maria Kuznetsova, Elena Gantsova, Elena Gantsova, Viktoria Kiseleva, Anastasiya Lokhonina, Anastasiya Lokhonina, Maria Antonova, Aiaz Mamedov, Anna Soboleva, Dmitry Trofimov, Timur Fatkhudinov, Timur Fatkhudinov, Gennady Sukhikh

Get full text

Serine Protease-Mediated Cutaneous Inflammation: Characterization of an Ex Vivo Skin Model for the Assessment of Dexamethasone-Loaded Core Multishell-Nanocarriers by Janna Frombach, Fiorenza Rancan, Katharina Kübrich, Fabian Schumacher, Michael Unbehauen, Ulrike Blume-Peytavi, Rainer Haag, Burkhard Kleuser, Robert Sabat, Kerstin Wolk, Annika Vogt

“…Among the various pathological alterations in inflamed skin, aberrant serine protease (SP) activity directly affects the biochemical environment in the superficial compartments, which interact with topically applied formulations. …”
Get full text

A rapid method for detecting and distinguishing metallo-β-lactamase-and serine carbapenemase-producing Enterobacteriales using MALDI-TOF MS by Xiaopeng Jing, Yanyan Hu, Tingting Wu, Xing Zhang, Shaofeng Luo, Wei Wang, Xiaochun Min, Ruiling Sun, Ji Zeng

Subjects: Get full text

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs by Yiting Guo, Fang He, Zhiying Deng, Jie Yin, Guiping Guan, Zhengjun Xie, Xihong Zhou

Subjects: Get full text

Serine protease inhibitor derived from Trichinella spiralis (TsSERP) inhibits neutrophil elastase and impairs human neutrophil functions by Porntida Kobpornchai, Onrapak Reamtong, Orawan Phuphisut, Preeyarat Malaitong, Poom Adisakwattana

Subjects: Get full text

A Novel Role for Plasminogen Activator Inhibitor Type-2 as a Hypochlorite-Resistant Serine Protease Inhibitor and Holdase Chaperone by Jordan H. Cater, Noralyn B. Mañucat-Tan, Demi K. Georgiou, Guomao Zhao, Irina A. Buhimschi, Amy R. Wyatt, Marie Ranson

Get full text

Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers by C. Ming Tse, Julie G. In, Jianyi Yin, Mark Donowitz, Michele Doucet, Jennifer Foulke-Abel, Fernando Ruiz-Perez, James P. Nataro, Nicholas C. Zachos, James B. Kaper, Olga Kovbasnjuk

Subjects: Get full text