Correction: Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming by Zhangnan Liu, Mengzhen Fan, Junqing Hou, Sijing Pan, Yanxin Xu, Hailong Zhang, Chen Liu, Xiangjun Hao, Xia Li, Huijuan Wang

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A novel tetratricopeptide repeat (TPR) containing PP5 serine/threonine protein phosphatase in the malaria parasite, <it>Plasmodium falciparum</it> by Adams Brian, Kumar Rajinder, Kar Bratati, Dobson Sean, Barik Sailen

“…</p> <p>Results</p> <p>We provide biochemical and sequence evidence for a protein serine/threonine phosphatase type PP5 in <it>Plasmodium falciparum,</it> and named it PfPP5. …”
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Serine-arginine splicing factor 2 promotes oesophageal cancer progression by regulating alternative splicing of interferon regulatory factor 3 by Ziqing Wei, Yuyao Wang, Wenyuan Ma, Wenqing Xing, Peng Lu, Zhijie Shang, Feng Li, Huiyu Li, Yuxuan Wang

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Spinal Excitatory Dynorphinergic Interneurons Contribute to Burn Injury-Induced Nociception Mediated by Phosphorylated Histone 3 at Serine 10 in Rodents by Angelika Varga, Zoltán Mészár, Miklós Sivadó, Tímea Bácskai, Bence Végh, Éva Kókai, István Nagy, Péter Szücs

“…The phosphorylation of serine 10 in histone 3 (p-S10H3) has recently been demonstrated to participate in spinal nociceptive processing. …”
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SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer by Tyler Sniegowski, Ksenija Korac, Yangzom D. Bhutia, Vadivel Ganapathy

“…Glutamine, serine, glycine, and methionine are obligatory to fuel these metabolic pathways. …”
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Remodeling Serine Synthesis and Metabolism via Nanoparticles (NPs)‐Mediated CFL1 Silencing to Enhance the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Senlin Li, Lei Xu, Guo Wu, Ziqi Huang, Linzhuo Huang, Fengqian Zhang, Chunfang Wei, Qian Shen, Rong Li, Lei Zhang, Xiaoding Xu

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Serine–Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2 by Duxan Arancibia, Matias Lira, Yocelin Cruz, Daniela P. Barrera, Carolina Montenegro-Venegas, Juan A. Godoy, Craig C. Garner, Nibaldo C. Inestrosa, Eckart D. Gundelfinger, Pedro Zamorano, Viviana I. Torres

“…The self-assembly and synaptic recruitment of the <i>Drosophila</i> protein Bruchpilot (BRP), a partial homolog of CAST1/ERC2, is modulated by the serine-arginine protein kinase (SRPK79D). Here, we demonstrate that overexpression of the vertebrate SRPK2 regulates the self-assembly of CAST1/ERC2 in HEK293T, SH-SY5Y and HT-22 cells and the CC1 and CC4 domains are involved in this process. …”
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Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma by Xiaobin Bai, Jia Wang, Longwei Huo, Yuchen Xie, Wanfu Xie, Gaofeng Xu, Maode Wang

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Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases by M.A.S. Medeiros, M.S.F. França, G. Boileau, L. Juliano, K.M. Carvalho

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Bioprocess Engineering, Transcriptome, and Intermediate Metabolite Analysis of L-Serine High-Yielding <i>Escherichia coli</i> W3110 by Chenyang Wang, Qinyu Li, Peng Zhou, Xiaojia Chen, Jiping Shi, Zhijun Zhao

Subjects: “…L-serine…”
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Eubacterium rectale Improves the Efficacy of Anti-PD1 Immunotherapy in Melanoma via l-Serine-Mediated NK Cell Activation by Nian Liu, Lihui Chen, Mingjie Yan, Qian Tao, Jie Wu, Jing Chen, Xiang Chen, Wei Zhang, Cong Peng

“…Mechanistically, supplementation with l-serine or application of an l-serine synthesis inhibitor affected NK cell activation through Fos/Fosl. …”
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Neuroinflammation aggravated by traumatic brain injury at high altitude is reversed by L-serine via NFAT1-mediated microglial polarization by Jinchun Liu, Jinchun Liu, Shunhua Peng, Lisha Ye, Yechao Sun, Qiong Zhao, Hua Wei, Qianqian Luo, Min He, Min He, Guohua Wang

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Simvastatin Resistance of <i>Leishmania amazonensis</i> Induces Sterol Remodeling and Cross-Resistance to Sterol Pathway and Serine Protease Inhibitors by Thais Tenorio Soares Fujii, Pollyanna Stephanie Gomes, Rubens Lima do Monte-Neto, Daniel Claudio de Oliveira Gomes, Marc Ouellette, Eduardo Caio Torres-Santos, Valter Viana Andrade-Neto, Herbert Leonel de Matos Guedes

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Serine and glycine metabolism-related gene expression signature stratifies immune profiles of brain gliomas, and predicts prognosis and responses to immunotherapy by Siliang Chen, Shuxin Zhang, Shuxin Zhang, Wentao Feng, Junhong Li, Yunbo Yuan, Wenhao Li, Zhihao Wang, Yuan Yang, Yanhui Liu

Subjects: “…serine…”
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High abundance of Serine/Threonine-rich regions predicted to be hyper-<it>O</it>-glycosylated in the secretory proteins coded by eight fungal genomes by González Mario, Brito Nélida, González Celedonio

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MbovP0725, a secreted serine/threonine phosphatase, inhibits the host inflammatory response and affects metabolism in Mycoplasma bovis by Hui Zhang, Yiqiu Zhang, Doukun Lu, Xi Chen, Yingyu Chen, Changmin Hu, Aizhen Guo

“…Here, we investigated a novel secreted protein, MbovP0725, from Mycoplasma bovis encoding a putative haloacid dehalogenase (HAD) hydrolase function of a key serine/threonine phosphatase depending on Mg2+ for the dephosphorylation of its substrate pNPP, and it was most active at pH 8 to 9 and temperatures around 40°C. …”
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Circulating Levels of Visceral Adipose Tissue-Derived Serine Protease Inhibitor (Vaspin) Appear as a Marker of Musculoskeletal Pain Disability by Nader Tarabeih, Alexander Kalinkovich, Adel Shalata, Gregory Livshits

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Fertilizing ability and survivability of rooster sperm diluted with a novel semen extender supplemented with serine for practical use on smallholder farms by Vibuntita Chankitisakul, Wuttigrai Boonkum, Theerapat Kaewkanha, Maruay Pimprasert, Ruthaiporn Ratchamak, Supakorn Authaida, Pachara Thananurak

“…The objective of this study was to examine the effect of a new rooster semen extender (hereinafter, NCAB) supplemented with serine on the survivability and fertilizing ability of sperm following storage. …”
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Serine Palmitoyltransferase Gene Silencing Prevents Ceramide Accumulation and Insulin Resistance in Muscles in Mice Fed a High-Fat Diet by Monika Imierska, Piotr Zabielski, Kamila Roszczyc-Owsiejczuk, Emilia Sokołowska, Karolina Pogodzińska, Iwona Kojta, Agnieszka Błachnio-Zabielska

“…In order to explore this topic further, we locally silenced the gene encoding serine palmitoyltransferase (SPT) in the gastrocnemius muscle of animals with HFD-induced insulin resistance. …”
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Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model by Laurel Robbins, Ariane Balaram, Stefanie Dejneka, Matthew McMahon, Zarina Najibi, Peter Pawlowicz, William H. Conrad

“…The first committed step towards D-CS synthesis is catalyzed by the L-serine-O-acetyltransferase (DcsE) which converts L-serine and acetyl-CoA to O-acetyl-L-serine (L-OAS). …”
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