-
7221
Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases
Published 2022-10-01“…To investigate the role of phosphorylation in regulating NPR1 and NPR2 guanylyl cyclase activity, we developed mouse lines in which regulatory serines and threonines were substituted with glutamates, to mimic the negative charge of the phosphorylated forms (NPR1-8E and NPR2-7E). …”
Get full text
Article -
7222
Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from <i>Tenebrio molitor</i>
Published 2022-08-01“…Additionally, our results reveal that a diet enriched with TM extracts restores the expression of 15 metabolites and 17 proteins mainly involved in biological pathways associated with blood pressure maintenance, such as the renin–angiotensin and kallikrein–kinin systems, serin protease inhibitors, reactive oxygen scavenging, and lipid peroxidation. …”
Get full text
Article -
7223
Methyl carbamates of phosphatidylethanolamines and phosphatidylserines reveal bacterial contamination in mitochondrial lipid extracts of mouse embryonic fibroblasts
Published 2023-08-01“…A specific lipid extraction performed on a couple of standard phosphatidyl-ethanolamines/-serines, based on purposely photo-oxidized chloroform and deuterated methanol, indicated route (i) as negligible in the specific case, thus highlighting the enzymatic route related to bacterial contamination as the most likely source of methyl carbamates. …”
Get full text
Article -
7224
DNA Aptamers against Vaccinia-Related Kinase (VRK) 1 Block Proliferation in MCF7 Breast Cancer Cells
Published 2021-05-01“…Vaccinia-related kinase (VRK) 1 is a serin/threonine kinase that plays an important role in DNA damage response (DDR), phosphorylating some proteins involved in this process such as 53BP1, NBS1 or H2AX, and in the cell cycle progression. …”
Get full text
Article -
7225
Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein
Published 2018-12-01“…This analysis revealed that two serines (S18, S98) and one tyrosine (Y97) are phosphorylated in the flexible N- and C-terminal regions of the protein. …”
Get full text
Article -
7226
Developing similarity matrices for antibody-protein binding interactions.
Published 2023-01-01“…The matrices exhibited both commonalities, such as mutations of aromatic and charged residues being the most detrimental, and differences, such as Rosetta predicting mutations of serines to be better tolerated than either Amber or CHARMM. …”
Get full text
Article -
7227
-
7228
-
7229
Breast Hemangioma Evaluation with Magnetic Resonance Imaging: A Rare Case Report
Published 2022-04-01Get full text
Article -
7230
-
7231
DeBi: Discovering Differentially Expressed Biclusters using a Frequent Itemset Approach
Published 2011-06-01Get full text
Article -
7232
Improving Spatial Coverage of Satellite Aerosol Classification Using a Random Forest Model
Published 2021-03-01Get full text
Article -
7233
Identification of a protein kinase activity that phosphorylates connexin43 in a pH-dependent manner
Published 2000-04-01“…Mutants of Cx43 which lack the serines between amino acids 364-374 could not be phosphorylated in the in vitro kinase reaction, indicating that this is a likely target of this reaction. …”
Get full text
Article -
7234
Investigation of physical risk factors in Kahramanmaraş Paper Mill
Published 2018-09-01Get full text
Article -
7235
Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43.
Published 2024-01-01“…One of the disease-specific features of TDP-43 inclusions is the aberrant phosphorylation of TDP-43 at serines 409/410 (pS409/410). Here, we developed rabbit monoclonal antibodies (mAbs) that specifically detect pS409/410-TDP-43 in multiple model systems and FTD/ALS patient samples. …”
Get full text
Article -
7236
Phosphorylation-Dependent Intra-Domain Interaction of the Cx37 Carboxyl-Terminus Controls Cell Survival
Published 2019-02-01“…As detected by mass spectrometry, Cx37 was phosphorylated at serines 275, 321, and 328; phosphomimetic mutations of these sites resulted in cell death when expressed in rat insulinoma cells. …”
Get full text
Article -
7237
Alkaline phosphatase interference in immuno-enzymatic assays
Published 2022-01-01Get full text
Article -
7238
-
7239
Prof Dr Ali Fuat Işık 1963-2005
Published 2005-12-01“…Birol DEMİREL KOCA ÇINAR Koca çınar sanırlardı Çürük hem de kof olduğu anlaşıldı Kökünden devrildi boylu boyunca Küçük bir fırtınada Haksızlık etmeyin O da yuva oldu böceklere kuşlara Şarkılar söyledi rüzgârlarla Serin gölgesi vardı sohbet masalarına Nereden bilsin çınarcık Kendi gövdesini de sulaması gerektiğini O dallara yapraklara özenirdi Daha çok yaranmak için insanlara kuşlara Devrilipte bulanınca toza toprağa Ne olduğunu anlamamıştı daha Gövdesini kökünü elledi bir bir Ve koyverdi bir ağıt.. …”
Get full text
Article -
7240
Utilization of rosemary (Rosmarinus officinalis L.) stalks in pulp and paper production
Published 2017-07-01Get full text
Article