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Sulfonyl fluoride analogues as activity-based probes for serine proteases.
Published 2012“…An alkyne-tagged sulfonyl fluoride covalently modifies members of the S1 family of serine proteases. By applying click chemistry, avidin enrichment and mass spectrometry, we can enrich and identify active endogenous serine proteases from a complex proteome.…”
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62
Bicyclic lactams derived from serine or cysteine and 2-methylpropanal
Published 2020“…Bicyclic lactams may be prepared from serine or cysteine and 2-methylpropanal; the resulting S,N-heterocycles are more stable than the corresponding O,N-heterocycles but both are synthetic intermediates capable of further elaboration.…”
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63
Unique regulation of the active site of the serine esterase S-formylglutathione hydrolase.
Published 2006“…While SFGHs do contain a conserved cysteine residue that has been implicated in catalysis, sequence analysis also reveals the classic catalytic triad of a serine hydrolase. Using a combination of selective protein modification and X-ray crystallography, AtSFGH from Arabidopsis thaliana has been shown to be a serine hydrolase rather than a cysteine hydrolase. …”
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64
Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila
Published 2022“…D-serine action requires binding to neuronal NMDA-type glutamate receptors. …”
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65
A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.
Published 2006“…The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. …”
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66
Serine esterases are required for pollen tube penetration of the stigma in Brassica
Published 2002“…Seven serine esterases were identified in pollen and at least seven serine esterases were identified in stigma. …”
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67
Impacts of pig farming on the water quality of Serin River , Sarawak
Published 2006“…Therefore, the objective of this study is to determine the impact of pig farm effluent on the water quality of Serin River and its tributaries. Results of analysis show that the tributary that received pond effluent has significantly higher mean of total suspended solids (TSS), biochemical oxygen demand (BOD5) chemical oxygen demand (COD), ammonia-nitrogen (NH3 -N), reactive phosphorus (SRP) and Escherichia coli (E. coli) concentrations when compared to those of the tributary that did not receive pond effluent. …”
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68
Electrochemical Detection of Olivetol Based on Poly(L-Serine) Film Layered Copper Oxide Modified Carbon Paste Electrode (p-L-Serine/CuO/CPE)
Published 2022-12-01Subjects: Get full text
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69
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The connection between innervation and metabolic rearrangements in pancreatic cancer through serine
Published 2022-12-01Get full text
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71
1-C Metabolism—Serine, Glycine, Folates—In Acute Myeloid Leukemia
Published 2021-02-01“…Recent studies have shown that in response to glutamine deprivation leukemia cells upregulate key enzymes in the serine biosynthesis pathway, suggesting that serine upregulation may be a targetable compensatory mechanism. …”
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72
Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers
Published 2023-05-01Subjects: “…Serine-glycine-one-carbon metabolism…”
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73
Chemical Modification of Silk Fibroin through Serine Amino Acid Residues
Published 2022-06-01Subjects: Get full text
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74
Intersection of Coagulation and Fibrinolysis by the Glycosylphosphatidylinositol (GPI)-Anchored Serine Protease Testisin
Published 2023-05-01Subjects: “…serine protease…”
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75
The new external drug for the treatment of psoriasis based on inhibition of serine proteases
Published 2021-07-01Subjects: Get full text
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76
Association between intrinsic disorder and serine/threonine phosphorylation in Mycobacterium tuberculosis
Published 2015-01-01Subjects: Get full text
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77
Serine phosphorylation regulates the P-type potassium pump KdpFABC
Published 2020-09-01Subjects: Get full text
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78
Prevalence and Homology of the Pneumococcal Serine-Rich Repeat Protein at the Global Scale
Published 2023-06-01“…Along with numerous pneumococcal surface protein immunogens, the pneumococcal serine-rich repeat protein (PsrP) has been investigated as a potential vaccine target due to its surface exposure and functions toward bacterial virulence and lung infection. …”
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Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro
Published 2023-06-01“…Summary: Serine/threonine protein phosphatase 2 (PP2A) forms heterotrimeric holoenzymes, where a scaffold subunit bridges the PP2A catalytic subunit to a B regulatory subunit, e.g., B55α. …”
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Role of Serine 310 in the Activity and Temperature Profile of Human Caspase-9
Published 2023-01-01“…It has been reported that phosphorylation of serine 310 in murine caspase-9 prevents enzyme processing. …”
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