Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes by Mischa P. Keizer, Mischa P. Keizer, Angela Kamp, Gerard van Mierlo, Taco W. Kuijpers, Taco W. Kuijpers, Diana Wouters

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Glycan-Dependent and -Independent Dual Recognition between DC-SIGN and Type II Serine Protease MSPL/TMPRSS13 in Colorectal Cancer Cells by Motohiro Nonaka, Shogo Matsumoto, Bruce Yong Ma, Hiroshi Kido, Nana Kawasaki, Nobuko Kawasaki, Toshisuke Kawasaki

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A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation by Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen

“…Recent studies have shown that transmembrane serine protease 2 (TMPRSS2), a protease known for similar role in previous coronavirus infections, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS), is responsible for the proteolytic cleavage of the SARS-CoV-2 spike protein, enabling host cell fusion of the virus. …”
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Regulatory effects of Trichinella spiralis serpin-type serine protease inhibitor on endoplasmic reticulum stress and oxidative stress in host intestinal epithelial cells by Jingbo Zhen, Lihao Lin, Zhixin Li, Feng Sun, Yang Han, Qiankun Li, Yuqi Yang, Xueting Liu, Junchen Yu, Qi Zhang, Yixin Lu, Caixia Han

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Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial by David Cipolla, Jimin Zhang, Brice Korkmaz, James D. Chalmers, Jessica Basso, Daniel Lasala, Carlos Fernandez, Ariel Teper, Kevin C. Mange, Walter R. Perkins, Eugene J. Sullivan

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The Immunomodulatory Effect of IrSPI, a Tick Salivary Gland Serine Protease Inhibitor Involved in <i>Ixodes ricinus</i> Tick Feeding by Adrien A. Blisnick, Ladislav Šimo, Catherine Grillon, Fabienne Fasani, Sébastien Brûlé, Bernard Le Bonniec, Eric Prina, Maud Marsot, Anthony Relmy, Sandra Blaise-Boisseau, Jennifer Richardson, Sarah I. Bonnet

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Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase Cascades by Cynthia E. Wilkins-Port, Stephen P. Higgins, Craig E. Higgins, Issey Kobori-Hotchkiss, Paul J. Higgins

“…Stringent controls on serine protease/MMP expression and their topographic activity are essential for maintaining tissue homeostasis. …”
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Aeruginosin 525 (AER525) from Cyanobacterium <i>Aphanizomenon</i> Sp. (KUCC C2): A New Serine Proteases Inhibitor by Donata Overlingė, Marta Cegłowska, Robert Konkel, Hanna Mazur-Marzec

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Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells by Wonhee Hur, Byung Yoon Kang, Sung Min Kim, Gil Won Lee, Jung-Hee Kim, Min-Kyung Nam, Hyangshuk Rhim, and Seung Kew Yoon

“…High-temperature requirement protein A2 (HtrA2/Omi), a mitochondrial serine protease with various functions, is responsible for quality control in mitochondrial homeostasis. …”
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Cloning, expression, and structural modeling of two alkaline serine protease genes from extremophilic Bacillaceae -related species: Application in valorization of invasive crustaceans by Sondes MECHRI, Khelifa BOUACEM, Fawzi ALLALA, Marwa KHALED, Amel BOUANANE-DARENFED, Hocine HACENE, Bassem JAOUADI

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Induction of IDO1 and kynurenine by serine proteases subtilisin, prostate specific antigen, CD26 and HtrA: a new form of immunosuppression? by Clanchy, FIL, Huang, Y-S, Ogbechi, J, Darlington, LG, Williams, RO, Stone, TW

“…Several serine proteases have been linked to autoimmune disorders and tumour initiation although the mechanisms are not fully understood. …”

Optimization of serine protease purification from mango (Mangifera indica cv. Chokanan) peel in polyethylene glycol/ dextran aqueous two phase system by Mehrnoush, Amid, Mustafa, Shuhaimi, Sarker, Md. Zaidul Islam, Abd Manap, Mohd Yazid

“…This could be due to the high hydrophobicity of serine protease compared to protein contaminates. The optimum conditions to achieve high partition coefficient (84.2) purification factor (14.37) and yield (97.3%) of serine protease were obtained in the presence of 8000 g·mol−1 of PEG, 17.2% of tie line length and 4.5% of NaCl at pH 7.5. …”
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Effects of extraction, purification and freeze drying conditions on enzymatic properties of serine protease from mango (Mangifera Indica L. Cv.Chokanan) peel by Amid, Mehrnoush

“…This research studies the extraction, purification, characterization and preservation by freeze drying of serine protease from mango (Mangifera Indica CV. Chokanan) peel. …”
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Structural and functional characterization of cleavage and inactivation of human serine protease inhibitors by the bacterial SPATE protease EspPα from enterohemorrhagic E. coli. by André Weiss, Hanna Joerss, Jens Brockmeyer

“…EspPα and EspI are serine protease autotransporters found in enterohemorrhagic Escherichia coli. …”
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Improving the Thermostability of Serine Protease PB92 from <i>Bacillus alcalophilus</i> via Site-Directed Mutagenesis Based on Semi-Rational Design by Huabiao Miao, Xia Xiang, Nanyu Han, Qian Wu, Zunxi Huang

“…In this work, we aimed to improve the thermostability of the serine protease PB92 from <i>Bacillus alcalophilus</i> to meet the high-temperature requirements of biotechnological treatments. …”
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Overexpression of a Novel Vacuolar Serine Protease-Encoding Gene (<i>spt1</i>) to Enhance Cellulase Production in <i>Trichoderma Reesei</i> by Cheng Yao, Ningning Sun, Weihao Gao, Yu Sun, Jiaxin Zhang, Hong Liu, Yaohua Zhong

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Studi molecular docking senyawa 1,5-benzothiazepine sebagai inhibitor dengue DEN-2 NS2B/NS3 serine protease by Neni Frimayanti, Anita Lukman, Livia Nathania

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Biochemical Aspects of a Serine Protease from Caesalpinia echinata Lam. (Brazilwood) Seeds: A Potential Tool to Access the Mobilization of Seed Storage Proteins by Priscila Praxedes-Garcia, Ilana Cruz-Silva, Andrezza Justino Gozzo, Viviane Abreu Nunes, Ricardo José Torquato, Aparecida Sadae Tanaka, Rita de Cássia Figueiredo-Ribeiro, Yamile Gonzalez Gonzalez, Mariana da Silva Araújo

“…It is strongly inhibited by TLCK, a serine protease inhibitor, but not by E-64, EDTA or pepstatin A. …”
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Oral Vaccination of Mice With Trichinella spiralis Putative Serine Protease and Murine Interleukin-4 DNA Delivered by Invasive Lactiplantibacillus plantarum Elicits Protective Immunity by Ying Xue, Ying Xue, Ying Xue, Bo Zhang, Bo Zhang, Bo Zhang, Nan Wang, Nan Wang, Nan Wang, Hai-Bin Huang, Hai-Bin Huang, Hai-Bin Huang, Yu Quan, Yu Quan, Yu Quan, Hui-Nan Lu, Hui-Nan Lu, Hui-Nan Lu, Zhi-Yu Zhu, Zhi-Yu Zhu, Zhi-Yu Zhu, Jun-Yi Li, Jun-Yi Li, Jun-Yi Li, Tian-Xu Pan, Tian-Xu Pan, Tian-Xu Pan, Yue Tang, Yue Tang, Yue Tang, Yan-Long Jiang, Yan-Long Jiang, Yan-Long Jiang, Chun-Wei Shi, Chun-Wei Shi, Chun-Wei Shi, Gui-Lian Yang, Gui-Lian Yang, Gui-Lian Yang, Chun-Feng Wang, Chun-Feng Wang, Chun-Feng Wang

“…In this study, the invasive bacterium Lactiplantibacillus plantarum (L. plantarum) expressing FnBPA was used as a carrier to deliver a novel oral DNA vaccine consisting of T. spiralis adult putative serine protease (Ts-ADpsp) and murine interleukin (IL)-4 DNA to mouse intestinal epithelial cells. …”
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Oral vaccination of mice with attenuated Salmonella encoding Trichinella spiralis calreticulin and serine protease 1.1 confers protective immunity in BALB/c mice by Sheng Jie Bai, Lu Lu Han, Ruo Dan Liu, Shao Rong Long, Xi Zhang, Jing Cui, Zhong Quan Wang

“…In this study, two novel T. spiralis genes (calreticulin and serine protease 1.1) in combination were used to construct oral DNA vaccines, and their induced protective immunity was evaluated in a murine model. …”
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