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Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers
Published 2023-11-01Subjects: Get full text
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Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.
Published 2012-01-01“…Specifically, the serine protease(s) acted on the N-terminal polymerising domain of the major intestinal mucin Muc2, resulting in depolymerisation of Muc2 polymers. …”
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New insights into the evolution of subtilisin-like serine protease genes in Pezizomycotina
Published 2010-03-01“…<p>Abstract</p> <p>Background</p> <p>Subtilisin-like serine proteases play an important role in pathogenic fungi during the penetration and colonization of their hosts. …”
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Thermostable serine protease inhibitor from Death cap (Amanita phalloides)
Published 2019-06-01“…Results: Death cap contained serine protease inhibitory activity. Molecular size of inhibitor was suspected to be less than 3 kDa. …”
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Mutation of Serine protease 1 Induces Male Sterility in Bombyx mori
Published 2022-02-01“…Serine proteases are important in reproduction, embryonic development, cell differentiation, apoptosis, and immunity. …”
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Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo.
Published 2015-01-01“…Contradicting earlier assumptions, our study found serine proteases dispensable for processing of proHNPs in vivo. …”
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Proton Bridging in Catalysis by and Inhibition of Serine Proteases of the Blood Cascade System
Published 2021-04-01“…The principal conclusion of this review is that proton sharing at distances below the sum of van der Waals radii of the hydrogen and both donor and acceptor atoms contribute to the remarkable catalytic prowess of serine proteases of the blood clotting system and other enzymes that employ acid-base catalysis. …”
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Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.
Published 2014-03-01“…Most attention has focused on the 'cercarial elastase' serine proteases that facilitate skin invasion by infective schistosome larvae, and the cysteine and aspartic proteases that worms use to digest the blood meal. …”
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Sugar promotes feeding in flies via the serine protease homologue scarface
Published 2018“…Here, we used Drosophila to understand how the brain responds to carbohydrate deprivation. We found that serine protease homologs (SPHs) are enriched among genes that are transcriptionally regulated in flies deprived of carbohydrates. …”
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Inherited deficiency of mannan-binding lectin-associated serine protease 2.
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Purification and biochemical characterization of alkaline serine protease from caesalpinia bonducella
Published 2010“…A high molecular weight serine protease has been purified to electrophoretic homogeneity from the seeds of Caesalpinia bonducella Hem. …”
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Bioinformatics analysis and molecular cloning of an extracellular serine protease from acinetobacter baumannii /
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Interaction of protein C inhibitor with the type II transmembrane serine protease enteropeptidase.
Published 2012-01-01“…The serine protease inhibitor protein C inhibitor (PCI) is expressed in many human tissues and exhibits broad protease reactivity. …”
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Inhibition of Serine Proteases as a Novel Therapeutic Strategy for Abdominal Pain in IBS
Published 2022-05-01“…Serine proteases are heavily present in the gastrointestinal tract where they are essential in numerous physiological processes. …”
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Dependence and Guidance Receptors—DCC and Neogenin—In Partial EMT and the Actions of Serine Proteases
Published 2020-02-01Subjects: Get full text
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