Showing 101 - 120 results of 2,893 for search '"serine protease"', query time: 0.16s Refine Results
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    Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder. by James J Valdés, Alexandra Schwarz, Israel Cabeza de Vaca, Eric Calvo, Joao H F Pedra, Victor Guallar, Michalis Kotsyfakis

    Published 2013-01-01
    “…This peptide inhibits several serine proteases with high affinity and was named tryptogalinin due to its high affinity for β-tryptase. …”
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  4. 104

    Exosome-Mediated Activation of the Prostasin-Matriptase Serine Protease Cascade in B Lymphoma Cells by Li-Mei Chen, Karl X. Chai

    Published 2023-07-01
    “…Prostasin and matriptase are extracellular membrane serine proteases with opposing effects in solid epithelial tumors. …”
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  5. 105

    Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections by Ebba Rosendal, Ionut Sebastian Mihai, Miriam Becker, Debojyoti Das, Lars Frängsmyr, B. David Persson, Gregory D. Rankin, Remigius Gröning, Johan Trygg, Mattias Forsell, Johan Ankarklev, Anders Blomberg, Johan Henriksson, Anna K. Överby, Annasara Lenman

    Published 2022-06-01
    “…The antiviral mechanism was found to be mediated by the inhibition of a serine protease, TMPRSS2, which results in a blockage of viral entry into target cells. …”
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    The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin. by Christine Gaboriaud, Rajesh Kumar Gupta, Lydie Martin, Monique Lacroix, Laurence Serre, Florence Teillet, Gérard J Arlaud, Véronique Rossi, Nicole M Thielens

    Published 2013-01-01
    “…To gain a first insight into the enzymatic and structural properties of MASP-3, a recombinant form of its serine protease (SP) domain was produced and characterized. …”
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  10. 110

    Transmembrane serine protease 6, a novel target for inhibition of neuronal tumor growth by Yong Zuo, Jiawei Bai, Huiyuan Bai, Siyu Tian, Hongtao Sun, Zhenhua Shi, Peng Yu, Guofen Gao, Yuan Li, Yan-Zhong Chang

    Published 2024-01-01
    “…Abstract Transmembrane serine protease 6 (Tmprss6) has been correlated with the occurrence and progression of tumors, but any specific molecular mechanism linking the enzyme to oncogenesis has remained elusive thus far. …”
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  11. 111

    Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA by Urszula Zarzecka, Alessandro Grinzato, Eaazhisai Kandiah, Dominik Cysewski, Paola Berto, Joanna Skorko-Glonek, Giuseppe Zanotti, Steffen Backert

    Published 2020-11-01
    “…An important bacterial virulence factor is the secreted serine protease HtrA (HtrACj), which targets tight and adherens junctional proteins in the gut epithelium. …”
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  12. 112

    HATL5: a cell surface serine protease differentially expressed in epithelial cancers. by Gregory S Miller, Gina L Zoratti, Andrew S Murray, Christopher Bergum, Lauren M Tanabe, Karin List

    Published 2014-01-01
    “…Here we demonstrate that HATL5 is a catalytically active serine protease that is inhibited by the two Kunitz type serine protease inhibitors, hepatocyte growth factor activator inhibitor (HAI)-1 and 2, as well as by serpinA1. …”
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    SPINK6 inhibits human airway serine proteases and restricts influenza virus activation by Dong Wang, Cun Li, Man Chun Chiu, Yifei Yu, Xiaojuan Liu, Xiaoyu Zhao, Jingjing Huang, Zhongshan Cheng, Shuofeng Yuan, Vincent Poon, Jian‐Piao Cai, Hin Chu, Jasper Fuk‐Woo Chan, Kelvin Kai‐Wang To, Kwok Yung Yuen, Jie Zhou

    Published 2022-01-01
    “…Abstract SPINK6 was identified in human skin as a cellular inhibitor of serine proteases of the KLK family. Airway serine proteases are required to cleave hemagglutinin (HA) of influenza A viruses (IAVs) to initiate an infection in the human airway. …”
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  15. 115

    Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections by Ben M. Flude, Giulio Nannetti, Paige Mitchell, Nina Compton, Chloe Richards, Meike Heurich, Andrea Brancale, Salvatore Ferla, Marcella Bassetto

    Published 2021-02-01
    “…MASP-2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway of complement activation. …”
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    Genome-wide identification and expression analysis of serine proteases and homologs in the silkworm <it>Bombyx mori</it> by Xu Ping-Zhen, Duan Jun, Dong Zhao-Ming, Wang Gen-Hong, Zhao Ping, Cheng Ting-Cai, Xiang Zhong-Huai, Xia Qing-You

    Published 2010-06-01
    “…<p>Abstract</p> <p>Background</p> <p>Serine proteases (SPs) and serine proteases homologs (SPHs) are a large group of proteolytic enzymes, with important roles in a variety of physiological processes, such as cell signalling, defense and development. …”
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    Recent Developments in Peptidyl Diaryl Phoshonates as Inhibitors and Activity-Based Probes for Serine Proteases by Marta Maślanka, Artur Mucha

    Published 2019-06-01
    “…Secondly, the phosphonates target exclusively serine proteases and leave other oxygen and sulfur nucleophiles intact. …”
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