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Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder.
Published 2013-01-01“…This peptide inhibits several serine proteases with high affinity and was named tryptogalinin due to its high affinity for β-tryptase. …”
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Exosome-Mediated Activation of the Prostasin-Matriptase Serine Protease Cascade in B Lymphoma Cells
Published 2023-07-01“…Prostasin and matriptase are extracellular membrane serine proteases with opposing effects in solid epithelial tumors. …”
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Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections
Published 2022-06-01“…The antiviral mechanism was found to be mediated by the inhibition of a serine protease, TMPRSS2, which results in a blockage of viral entry into target cells. …”
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Serine proteases in the extracellular preparations of Phytophthora infestans: does their presence relate to the aggressiveness of the pathogen?
Published 2002-06-01Subjects: Get full text
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Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties
Published 2010-06-01Subjects: Get full text
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The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult
Published 2022-06-01Subjects: “…serine protease inhibitor…”
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The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin.
Published 2013-01-01“…To gain a first insight into the enzymatic and structural properties of MASP-3, a recombinant form of its serine protease (SP) domain was produced and characterized. …”
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Transmembrane serine protease 6, a novel target for inhibition of neuronal tumor growth
Published 2024-01-01“…Abstract Transmembrane serine protease 6 (Tmprss6) has been correlated with the occurrence and progression of tumors, but any specific molecular mechanism linking the enzyme to oncogenesis has remained elusive thus far. …”
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Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA
Published 2020-11-01“…An important bacterial virulence factor is the secreted serine protease HtrA (HtrACj), which targets tight and adherens junctional proteins in the gut epithelium. …”
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HATL5: a cell surface serine protease differentially expressed in epithelial cancers.
Published 2014-01-01“…Here we demonstrate that HATL5 is a catalytically active serine protease that is inhibited by the two Kunitz type serine protease inhibitors, hepatocyte growth factor activator inhibitor (HAI)-1 and 2, as well as by serpinA1. …”
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Serine protease activities in Oxysarcodexia thornax (Walker) (Diptera: Sarcophagidae) first instar larva
Published 2008-08-01Subjects: “…chymotrypsin-like serine proteases…”
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SPINK6 inhibits human airway serine proteases and restricts influenza virus activation
Published 2022-01-01“…Abstract SPINK6 was identified in human skin as a cellular inhibitor of serine proteases of the KLK family. Airway serine proteases are required to cleave hemagglutinin (HA) of influenza A viruses (IAVs) to initiate an infection in the human airway. …”
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Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
Published 2021-02-01“…MASP-2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway of complement activation. …”
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Identification and functional analysis of serine protease inhibitor gene family of Eocanthecona furcellata (Wolff)
Published 2023-09-01Subjects: Get full text
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Production of serine protease inhibitors by mutagenesis and their effects on the mortality of Aedes aegypti L. larvae
Published 2015-10-01Subjects: Get full text
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Host serine protease ACOT2 assists DENV proliferation by hydrolyzing viral polyproteins
Published 2024-01-01Subjects: Get full text
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Genome-wide identification and expression analysis of serine proteases and homologs in the silkworm <it>Bombyx mori</it>
Published 2010-06-01“…<p>Abstract</p> <p>Background</p> <p>Serine proteases (SPs) and serine proteases homologs (SPHs) are a large group of proteolytic enzymes, with important roles in a variety of physiological processes, such as cell signalling, defense and development. …”
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Recent Developments in Peptidyl Diaryl Phoshonates as Inhibitors and Activity-Based Probes for Serine Proteases
Published 2019-06-01“…Secondly, the phosphonates target exclusively serine proteases and leave other oxygen and sulfur nucleophiles intact. …”
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