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1601
Injectable cell transplantation system for cytokine-based cancer immunotherapy
Published 2009“…Local, targeted delivery of cytokines in tumour sites is beneficial to achieve high therapeutic dose within tumour while limiting systemic dose. …”
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Final Year Project (FYP) -
1602
Metal sulfides for electrochemical energy storage and conversion
Published 2017“…The relevant studies in the thesis are divided into five parts, including Ni3S2@MoS2 core/shell nanorod arrays on Ni foam as the supercapacitor electrode (Chapter 4), honeycomb-like MoS2 nanoarchitectures anchored into graphene foam (GF) for enhanced lithium storage (Chapter 5), MoS2 architectures supported on graphene foam/carbon nanotube (GF/CNT) hybrid films: highly integrated frameworks with ideal contact for superior lithium storage (Chapter 6), MoS2 nanosheets decorated Ni3S2@MoS2 coaxial nanofibers for enhanced Na-ion storage (Chapter 7) and active sites–enriched hierarchical MoS2 nanotubes: highly active and stable architecture for boosting hydrogen evolution and lithium storage (Chapter 8). …”
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Thesis -
1603
Eliciting and honouring end-of-life care preferences : a multiple methods study on place of death
Published 2018“…Further, given that most deaths still occurred in hospitals, hospitals must continue to be viable sites where high-quality end-of-life care is available.…”
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Thesis -
1604
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1605
The role of calcium dependent neurotransmission in axon path finding, myelination and maintenance of specified cortical projection neuron populations
Published 2018“…</p> <p>One way to reduce neuronal activity was to abolish regulated vesicular release by removing Snap25 (synaptosome-associated protein of 25 kDA), member of the SNARE ((N-ethylmaleimide-sensitive factor) Attachment Protein Receptor) complex in a Snap25-flox mouse in which the essential exon 5a/b is flanked by LoxP sites and therefore truncated in the presence of Cre-recombinase. …”
Thesis -
1606
The influence of nicotinic acid adenine dinucleotide phosphate (NAADP) signalling and the significance of the organization of lysosomes in cardiac myocytes
Published 2017“…Data from confocal microscopy experiments demonstrate an association between lysosomes and the SR, while membrane contact sites (MCS) between these structures are shown to exist using electron microscopy. …”
Thesis -
1607
Sustainable management of elasmobranchs in complex coastal fisheries
Published 2024“…I examined fishing and trade motivations across the spectrum of elasmobranch catch, from low-value bycatch (like rhino rays) to high-value target species (like blacktip sharks) at two case study sites; Goa and Kakinada. My research uncovered diverse motivations and values underpinning people’s use of elasmobranchs, including instrumental (economic) benefits, food, culture and tradition, which were enabled by mechanisms such as access to capital, social identity and knowledge. …”
Thesis -
1608
Understanding the viral protein structures of clinically relevant arboviruses and fragment-based screening for antivirals
Published 2020“…Inhibition of this protein was frequently found to be effective in suppressing viral replication in vitro, while the efficacy is limited by drug dissemination to viral replication sites in vivo. Herein, fragment-based screening was applied to CHIKV nsP2 protease to identify novel start points for drug design. …”
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Thesis-Doctor of Philosophy -
1609
Structure-activity relationships of photo-activated soft tissue Adhesive
Published 2022“…Using tissue adhesives may reduce these, however soft tissue adhesion remains a challenging problem due to the presence of hydration layer on the tissue surface and the limited availability of covalent bonding sites for the adhesive to adhere onto the tissue. …”
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Thesis-Doctor of Philosophy -
1610
Defect chemistry in 2D atomic layers for energy photocatalysis
Published 2023“…Moreover, these defect configurations provide specific reactive sites to bind with different molecules, tuning the intermediate formation and facilitating reaction progression. …”
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Journal Article -
1611
Development of squaraine and croconaine probes for theranostic applications
Published 2025“…SQR29 was incorporated into a natural lignin hydrogel, allowing localized and targeted treatment at infected sites. Simultaneously, the hydrogel effectively scavenged free radicals to mitigate oxidative stress and promoted wound healing. …”
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Thesis-Doctor of Philosophy -
1612
The effects and costs of an anti-bullying program (KiVa) in UK primary schools: a multicenter cluster randomized controlled trial
Published 2024“…<p><b>Findings </b></p> Between 8/11/2019–12/02/2021, 118 primary schools were recruited in four trial sites, 11 111 students in primary analysis (KiVa-intervention: n = 5944; 49.6% female; UP: n = 5167, 49.0% female). …”
Journal article -
1613
Studies on the physicochemical, biomechanical and biological properties of novel decellularized bovine scaffold for bone regeneration
Published 2024“…The study found that DCC scaffolds significantly promoted new bone formation, with enhanced defect closure and higher bone density observed in micro-CT analyses compared to DMB. DCC sites also demonstrated elevated mRNA levels of osteogenic markers such as osteonectin, osteopontin, and osteocalcin. …”
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Thesis -
1614
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system
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Journal Article -
1615
Relevance judgment during health information seeking on a discussion forum
Published 2016“…In addition to authoritative health information websites maintained by healthcare organizations and government agencies, social media sites are increasingly being accessed to obtain and share patients’ experiences of diseases and treatments. …”
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Thesis -
1616
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1617
PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder
Published 2019“…The toroidal structure of a PCNA trimer makes it a sliding clamp protein, which utilizes its interdomain connecting loop (IDCL) interacting with PIP-box containing proteins to recruit these clients to sites of DNA replication to enable their functions. …”
Thesis -
1618
An epigenetic analysis of planarian stem cells
Published 2018“…In the future, we hope to be able to build gene regulatory networks by identifying TF-binding sites in open chromatin regions and elucidating enhancer targets in a range of planarian cell types. …”
Thesis -
1619
Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells
Published 2019“…In somatic cells, however, which have little or no telomerase activity, short telomeres are recognized as sites of DNA damage, resulting in an irreversible cell-cycle withdrawal known as “cellular senescence”. …”
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Thesis -
1620
Investigation of transition metal oxides as electrocatalysts for water oxidation
Published 2021“…It is identified that the metal-oxygen hybridization at active sites (defined as the percentage of O 2p states that hybridize with TM 3d states), which also follows a volcano-shaped trend with the Cr content, governs the OER activity of ZnFe2–xCrxO4. …”
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Thesis-Doctor of Philosophy