Glycosylation: A “Last Word” in the Protein-Mediated Biomineralization Process by John Spencer Evans

Get full text

Growth disorders caused by variants in epigenetic regulators: progress and prospects by Julian C. Lui

“…In this review, we highlight the connection between epigenetic modifications, genetic variants in epigenetic regulators and childhood growth disorders being established over the past decade, discuss their insights into skeletal biology, and the potential of epidrugs as a new type of therapeutic intervention.…”
Get full text

The role of bone marrow adipocytes in bone metastasis by Emma V. Morris, Claire M. Edwards

“…Bone marrow adipocytes act as local regulators of skeletal biology and homeostasis, with recent studies suggesting that marrow adipose tissue is metabolically active, and can function as an endocrine organ. …”
Get full text

Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis by Rebecca Mae Black, Lisa L. Flaman, Karin Lindblom, Susan Chubinskaya, Alan J. Grodzinsky, Patrik Önnerfjord

Get full text

Small changes in thermoregulation influence cancellous bone turnover balance in distal femur metaphysis in growing female mice by Lara H. Sattgast, Carmen P. Wong, Adam J. Branscum, Dawn A. Olson, Allan M. Aguirre-Burk, Urszula T. Iwaniec, Russell T. Turner

Get full text

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss by Seyed Ali Elahi, Seyed Ali Elahi, Petri Tanska, Rami K. Korhonen, Rik Lories, Nele Famaey, Ilse Jonkers, Ilse Jonkers

Get full text

Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study by Dovile Sinkeviciute, Anders Aspberg, Yi He, Anne-Christine Bay-Jensen, Patrik Önnerfjord

Get full text

Regulation of bone homeostasis by MERTK and TYRO3 by Janik Engelmann, Jennifer Zarrer, Victoria Gensch, Kristoffer Riecken, Nikolaus Berenbrok, The Vinh Luu, Antonia Beitzen-Heineke, Maria Elena Vargas-Delgado, Klaus Pantel, Carsten Bokemeyer, Somasekhar Bhamidipati, Ihab S. Darwish, Esteban Masuda, Tal Burstyn-Cohen, Emily J. Alberto, Sourav Ghosh, Carla Rothlin, Eric Hesse, Hanna Taipaleenmäki, Isabel Ben-Batalla, Sonja Loges

Get full text

The Multifactorial Role of Peripheral Nervous System in Bone Growth by Ioannis Gkiatas, Dimitrios Papadopoulos, Emilios E. Pakos, Ioannis Kostas-Agnantis, Ioannis Gelalis, Marios Vekris, Anastasios Korompilias

“…The purpose of this mini-review is to present the most recent data concerning the influence of innervation on bone growth, the current understanding of the skeletal innervation and their proposed physiological effects on bone metabolism as well as the implication of denervation in human skeletal biology in the developing organism since the peripheral neural trauma as well as peripheral neuropathies are common and they have impact on the growing skeleton.…”
Get full text

Bone marrow adipose tissue: a new player in cancer metastasis to bone by Morris, E, Edwards, C

“…The ability of bone marrow adipocytes to regulate skeletal biology and hematopoiesis, combined with their metabolic activity, endocrine functions, and proximity to tumor cells means that they are ideally placed to impact both tumor growth and bone disease. …”

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volu... by Greetje Vande Velde, Jennifer Poelmans, Ellen De Langhe, Amy Hillen, Jeroen Vanoirbeek, Uwe Himmelreich, Rik J. Lories

Get full text

From ELISA to Immunosorbent Tandem Mass Spectrometry Proteoform Analysis: The Example of CXCL8/Interleukin-8 by Mieke Metzemaekers, Sara Abouelasrar Salama, Jennifer Vandooren, Anneleen Mortier, Rik Janssens, Sofie Vandendriessche, Eva Ganseman, Erik Martens, Mieke Gouwy, Barbara Neerinckx, Patrick Verschueren, Lien De Somer, Carine Wouters, Sofie Struyf, Ghislain Opdenakker, Jo Van Damme, Paul Proost

Get full text

Heparan Sulfate: A Regulator of White Adipocyte Differentiation and of Vascular/Adipocyte Interactions by J. Michael Sorrell, Arnold I. Caplan

Get full text

BoneJ2 - refactoring established research software [version 1; peer review: 2 approved, 1 approved with reservations] by Richard Domander, Alessandro A Felder, Michael Doube

“…We reimplemented BoneJ, our software for skeletal biology image analysis, to address design limitations that put it at risk of becoming unusable. …”
Get full text

Hyaluronan: its potential application in intervertebral disc regeneration by Bojiang Shen, Aiqun Wei, Divya Bhargav, et al

“…George Hospital, The University of New South Wales, Sydney, AustraliaAbstract: Hyaluronan (HA) is a ubiquitous component of extracellular matrix in human tissues with diverse functions in skeletal biology. The biophysical properties of HA, such as high viscosity, elasticity and highly negative charge, make it useful in various therapeutic procedures. …”
Get full text

Impact of mechanical stretch on the cell behaviors of bone and surrounding tissues by Hye-Sun Yu, Jung-Ju Kim, Hae-Won Kim, Mark P Lewis, Ivan Wall

Get full text

Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo by Mei Massengale, Justin L. Massengale, Catherine R. Benson, Ninib Barywano, Toshihiko Oki, Matthew L. Steinhauser, Alissa Wang, Deepak Balani, Luke S. Oh, Mark A. Randolph, Thomas J. Gill III, Henry M. Kronenberg, David T. Scadden

“…These findings have implications for skeletal biology and regenerative medicine for joint injury repair.…”
Get full text

Preliminary Investigations of The Bioarchaeology of Medieval Giecz (XI-XII C.): Examples of Trauma and Stress by Agnew Amanda M., Justus Hedy M.

Get full text

A platform for automated and label-free monitoring of morphological features and kinetics of spheroid fusion by Thomas Deckers, Thomas Deckers, Thomas Deckers, Gabriella Nilsson Hall, Gabriella Nilsson Hall, Ioannis Papantoniou, Ioannis Papantoniou, Ioannis Papantoniou, Jean-Marie Aerts, Jean-Marie Aerts, Veerle Bloemen, Veerle Bloemen

Get full text

Appendage Regeneration in Vertebrates: What Makes This Possible? by Valentina Daponte, Przemko Tylzanowski, Antonella Forlino

Get full text