Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration by Debabrata Dey, Shir Marciano, Anna Poryval, Ondřej Groborz, Lucie Wohlrabova, Tomás Slanina, Gideon Schreiber

Subjects: Get full text

Progress in Lactate Metabolism and Its Regulation via Small Molecule Drugs by Jin Liu, Feng Zhou, Yang Tang, Linghui Li, Ling Li

Subjects: Get full text

Pathogenic sphingosine 1-phosphate pathway in psoriasis: a critical review of its pathogenic significance and potential as a therapeutic target by Yuechun Zhao, Yuheng Zhang, Jiaqi Li, Ningxin Zhang, Qiubai Jin, Yuxia Qi, Ping Song

Subjects: Get full text

Targets of tumor microenvironment for potential drug development by Ling Zhang, Ziruoyu Wang, Kailu Liu, Yihang Liu, Shuai Wang, Wei Jiang, Fanghui Lu, Yongjun Dang

Subjects: Get full text

Expert opinion on translational research for advanced glioblastoma treatment by Xiaoteng Cui, Yunfei Wang, Junhu Zhou, Qixue Wang, Chunsheng Kang

Subjects: Get full text

Small molecule agents for triple negative breast cancer: Current status and future prospects by Yan Ou, Mengchao Wang, Qian Xu, Binxu Sun, Yingjie Jia

Subjects: Get full text

Hybrid Quinoline-Sulfonamide Complexes (M²⁺) Derivatives with Antimicrobial Activity by Dumitrela Diaconu, Violeta Mangalagiu, Dorina Amariucai-Mantu, Vasilichia Antoci, Cristian Levente Giuroiu, Ionel I. Mangalagiu

Subjects: Get full text

Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death by Tove Selvin, Malin Berglund, Lena Lenhammar, Malin Jarvius, Peter Nygren, Mårten Fryknäs, Rolf Larsson, Claes R Andersson

Subjects: Get full text

Medical management of Crohn’s disease: state of the art and future perspectives by Fabio Salvatore Macaluso

Subjects: Get full text

Drug tendering: drug supply and shortage implications for the uptake of biosimilars by Dranitsaris G, Jacobs I, Kirchhoff C, Popovian R, Shane LG

Subjects: Get full text

Identification of hub genes and small-molecule compounds in medulloblastoma by integrated bioinformatic analyses by Zhendong Liu, Ruotian Zhang, Zhenying Sun, Jiawei Yao, Penglei Yao, Xin Chen, Xinzhuang Wang, Ming Gao, Jinzhao Wan, Yiming Du, Shiguang Zhao

Subjects: Get full text

Catalysts of Healing: A Symphony of Synthesis and Clinical Artistry in Small-Molecule Agents for Breast Cancer Alleviation by Jing Hu, Bi-Yue Zhu, Zhen-Xi Niu

Subjects: Get full text

Advances in biological agents in the treatment of inflammatory bowel disease by Na LI, Mei YE

Subjects: Get full text

Development Time and Patent Extension for Prescription Drugs in Canada: A Cohort Study by Joel Lexchin

Subjects: Get full text

Progress in immune pathogenesis and targeted therapy of alopecia areata by Jiali WANG, Dantong CHENG, Nana LUO, Pingsheng HAO

Subjects: Get full text

Editorial: Imaging Technology in Oncology Pharmacological Research by Qi Zeng, Xu Cao, Jinchao Feng, Hong Shan, Xueli Chen

Subjects: Get full text

The effects of different amounts of drug microspheres on the vivo and vitro performance of the PLGA/β-TCP scaffold by Liulan Lin, Tianjiang Wang, Qi Zhou, Niandong Qian

Subjects: Get full text

Novel Therapeutic Options for People with Ulcerative Colitis: An Update on Recent Developments with Janus Kinase (JAK) Inhibitors by Troncone E, Marafini I, Del Vecchio Blanco G, Di Grazia A, Monteleone G

Subjects: Get full text

Nanocarriers for intracellular co-delivery of proteins and small-molecule drugs for cancer therapy by Zhihong Cheng, Zhihong Cheng, Yongshuang Li, Duoyi Zhao, Wei Zhao, Meng Wu, Weilin Zhang, Yan Cui, Peng Zhang, Zhiyu Zhang

Subjects: Get full text

Review of Advanced Drug Trials Focusing on the Reduction of Brain Beta-Amyloid to Prevent and Treat Dementia by Decourt B, Noorda K, Noorda K, Shi J, Sabbagh MN

Subjects: Get full text