Replication of association of IL-1 gene cluster members with ankylosing spondylitis (AS) in Taiwanese Chinese. by Timms, A, Chou, C, Wei, J, Tsai, W, Wordsworth, B, Brown, M

Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese. by Chou, C, Timms, A, Wei, J, Tsai, W, Wordsworth, B, Brown, M

“…OBJECTIVE: To test the association of interleukin 1 (IL1) gene family members with ankylosing spondylitis (AS), previously reported in Europid subjects, in an ethnically remote population. …”

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. by Reveille, J, Sims, A, Danoy, P, Evans, D, Leo, P, Pointon, J, Jin, R, Zhou, X, Bradbury, L, Appleton, L, Davis, J, Diekman, L, Doan, T, Dowling, A, Duan, R, Duncan, E, Farrar, C, Hadler, J, Harvey, D, Karaderi, T, Mogg, R, Pomeroy, E, Pryce, K, Taylor, J, Savage, L

“…To identify susceptibility loci for ankylosing spondylitis, we undertook a genome-wide association study in 2,053 unrelated ankylosing spondylitis cases among people of European descent and 5,140 ethnically matched controls, with replication in an independent cohort of 898 ankylosing spondylitis cases and 1,518 controls. …”

Ankylosing spondylitis: evidence for a non-HLA-B*27 protective effect - Reply by Brown, M, Wordsworth, P

Confirmation of non-MHC genetic loci by whole genome linkage studies in ankylosing spondylitis. by Brown, M, Laval, S, Timms, A, Bradbury, L, Edwards, S, Rubin, L, Siminovitch, K, Calin, A, Wordsworth, P

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis by Georges, M, Laukens, D, Libioulle, C, Sandor, C, Mni, M, Cruyssen, B, Peeters, H, Elewaut, D, De Vos, M

“…To gain insight into the genetic overlap between CD and ankylosing spondylitis (AS), these markers were tested for association in AS patients. …”

Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci. by Laval, S, Timms, A, Edwards, S, Bradbury, L, Brophy, S, Milicic, A, Rubin, L, Siminovitch, K, Weeks, D, Calin, A, Wordsworth, B, Brown, M

“…Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. …”

The role of NK family receptor interactions with HLA-B27 in Ankylosing Spondylitis pathogenesis by Giles, J

Th17 cells expressing KIR3DL2+are increased in ankylosing spondylitis by Ridley, A, Kollnberger, S, Shaw, J, Wong, I, Chan, A, Cummings, F, Fleming, M, Bowness, P

THE IL1 GENE CLUSTER IS A MAJOR LOCUS DETERMINING SUSCEPTIBILITY TO ANKYLOSING SPONDYLITIS by Timms, A, Crane, A, Sims, A, Cordell, H, Bradbury, L, Beynon, O, Duff, G, Cardon, L, Calin, A, Wordsworth, P, Brown, M

Fine-mapping of the IL-1 gene cluster pinpoints genetic associations with ankylosing spondylitis. by Sims, A, Timms, A, Pointon, J, Bradbury, L, Wordsworth, B, Brown, M

The IL1 gene cluster is a major locus determining susceptibility to Ankylosing spondylitis. by Timms, A, Crane, A, Sims, A, Bradbury, L, Beynon, O, Coyne, M, Herzberg, I, Abbott, A, Cardon, L, Duff, G, Calin, A, Wordsworth, P, Brown, M

A study on homocysteine-specific CTL from patients with ankylosing spondylitis and reactive arthritis by Gao, X, Chilvers, M, Wordsworth, P

The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. by Timms, A, Crane, A, Sims, A, Cordell, H, Bradbury, L, Abbott, A, Coyne, MR, Beynon, O, Herzberg, I, Duff, G, Calin, A, Cardon, L, Wordsworth, B, Brown, M

“…Ankylosing spondylitis (AS) is a common and highly heritable inflammatory arthropathy. …”

Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway. by Wright, C, Edelmann, M, diGleria, K, Kollnberger, S, Kramer, H, McGowan, S, McHugh, K, Taylor, S, Kessler, B, Bowness, P

“…OBJECTIVES: To determine if peripheral blood monocytes from patients with ankylosing spondylitis (AS) differed in protein expression compared to rheumatoid arthritis (RA) and healthy controls (HC). …”

In-patient regime for the treatment of ankylosing spondylitis: an appraisal of improvement in spinal mobility and the effects of corticotrophin. by Wordsworth, B, Pearcy, M, Mowat, A

“…Twenty-one patients with ankylosing spondylitis were admitted for two weeks bedrest, postural and mobilizing exercises. …”

Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study by Reveille, J, Zhou, X, Bradbury, L, Cardon, L, Davis, J, Deloukas, P, Evans, D, Keniry, A, McGinnis, R, Pointon, J, Ward, M, Weisman, M, Wordsworth, P, Brown, M

Neck pain is a major clinical problem in ankylosing spondylitis, and impacts on driving and safety. by Holden, W, Taylor, S, Stevens, H, Wordsworth, P, Bowness, P

The Potential of a CT-Based Machine Learning Radiomics Analysis to Differentiate Brucella and Pyogenic Spondylitis by Yasin P, Mardan M, Abliz D, Xu T, Keyoumu N, Aimaiti A, Cai X, Sheng W, Mamat M

Subjects: “…brucella spondylitis…”
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Serum bone-turnover biomarkers are associated with the occurrence of peripheral and axial arthritis in psoriatic disease: a prospective cross-sectional comparative study by Deepak R. Jadon, Raj Sengupta, Alison Nightingale, Hui Lu, Juliet Dunphy, Amelia Green, James T. Elder, Rajan P. Nair, Eleanor Korendowych, Mark A. Lindsay, Neil J. McHugh

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