Paleoanthropological Analysis of Osteological Material from the Myntobe Burial Ground by Gursoy M., Baitanayev Bauyrzhan A., Acar Emel, Sizdikov Bagdaulet S.

“…The skeletons found were analyzed macroscopically and many diseases were identified, such as osteoarthritis (joint deformity), osteopathy, ankylosing spondylitis, heel spurs, thickening of the cranial bone, and deformity of the mandibular joint. …”
Get full text

Functional significance of the rare rs35667974 IFIH1 gene polymorphism, associated with multiple autoimmune diseases, using a structural biological approach by Maria I. Zervou, Athena C. Andreou, Elias E. Eliopoulos, George N. Goulielmos

“…Recently, this variant was found to be also associated with ankylosing spondylitis (AS), Crohn’s disease (CD) and ulcerative colitis (UC). …”
Get full text

Research progress on complications of Brucellosis by Min Jin, Min Jin, Zixu Fan, Ruifang Gao, Xingnan Li, Zhixiang Gao, Zhanli Wang

“…Of these, osteoarticular involvement is the most common complication, with a prevalence of approximately 2-77%, usually manifesting as spondylitis, sacroiliac arthritis and peripheral arthritis. …”
Get full text

Causal association between common rheumatic diseases and glaucoma: a Mendelian randomization study by Yang Meng, Zongbiao Tan, Yu Su, Lu Li, Changzheng Chen

“…Here, we performed a Mendelian randomization (MR) analysis to investigate the causal effects of six common rheumatic diseases on glaucoma.MethodsSix rheumatic diseases were included: ankylosing spondylitis (AS), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Sicca syndrome/Sjögren’s sydrome (SS), dermatomyositis (DM), and gout. …”
Get full text

Quality of life in patients with psoriatic arthritis by Kseniya Mikhailovna Koreshkova, Zarema Rimovna Khismatullina

“…In terms of the rate of progression, deterioration of the quality of life and disability, PsA patients are comparable to rheumatoid arthritis and ankylosing spondylitis. Purpose: to study the effect of psoriatic arthritis on the quality of life of patients. …”
Get full text

Role of Synovial Exosomes in Osteoclast Differentiation in Inflammatory Arthritis by Ji Eun Song, Ji Soo Kim, Ji Hye Shin, Ki Won Moon, Jin Kyun Park, Kyong Soo Park, Eun Young Lee

“…Exosomes isolated from synovial fluid of rheumatoid arthritis (RA), ankylosing spondylitis (AS), gout, and osteoarthritis (OA) patients were co-incubated with CD14+ mononuclear cells from healthy donors without macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor kappa-B ligand (RANKL). …”
Get full text

A study of clinical, radiological features and HLA-B27 serology of axial spondyloarthropathy with comparison of radiographic and non-radiographic disease by Manaswini Edara, Varsha Bhatt, Abhishek Zanwar, Kavya Koneru, Aditi M Patel, Pranav Jawade

“…Conclusion: Ankylosing spondylitis in western India occurs mostly in the age group of 20–30 years, suggesting affection of productive age group. …”
Get full text

Correlation of Interleukin-17 and 23 Inflammatory Markers with Genetically Transmitted Spondyloarthritis Patients at a Tertiary Care Facility, South India by T. Jayaprakash, K.V. Leela, Balamurali Venkatesan, Sujith Ravi, Om Lokesh Muthamilan

“…Among 289 SpA patients, 60% (172) were males, and 40% (117) were females, with a ratio of 1.5:1. Ankylosing Spondylitis (65.1%) was found to be the most prevalent subgroup of SpA among the patients, closely followed by reactive arthritis (21%), psoriatic arthritis (10.7%), undifferentiated spondyloarthritis (2.1%), and inflammatory bowel disease with associated arthritis (1%). …”
Get full text

The use of biosimilars as a new approach to the treatment of rheumatoid arthritis by N. V. Chichasova, A. M. Lila

“…It is indicated that Erelzi is registered in the Russian Federation for the treatment of RA, various variants of axial spondylitis, psoriatic arthritis, psoriasis and juvenile idiopathic arthritis.…”
Get full text

Perioperative management of patients with rheumatic disorders: problems and solutions by A. A. Klimenko, A. A. Kondrashov

“…In the group of patients with RD, namely with ankylosing spondylitis and psoriatic arthritis, prevention of heterotopic ossification after orthopedic manipulations, endoprosthesis is very important. …”
Get full text

Use of Janus kinase inhibitors in the treatment of immunoinflammatory rheumatic diseases: safety issues by B. S. Belov, N. V. Muravyeva, G. M. Tarasova, M. M. Baranova

“…To date, i-JAKs have been actively used and studied in various immunoinflammatory rheumatic diseases (IIRDs) – rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), as well as psoriasis, atopic dermatitis and inflammatory bowel disease. …”
Get full text

Relationship between systemic inflammatory response and hypercoagulation in patients with immuno-inflammatory rheumatic diseases by Yu. A. Zhuravleva, E. Yu. Gusev

“…The aim: to carry out a comparative analysis of the severity of the systemic inflammatory response in patients with immuno- inflammatory rheumatic diseases depending on the manifestations of hypercoagulation.To achieve the aim, a comparative analysis of proinflammatory markers (IL-6, IL-8, IL-10, TNFα, sIL-2R, CRP, ECP, β2-microglobulin) in the blood of patients with immune-inflammatory rheumatic diseases (systemic lupus erythematosus, rheumatoid arthritis, reactive arthritis, ankylosing spondylitis, psoriatic arthritis, rheumatic heart disease) was performed. …”
Get full text

Exploring radiographic patterns of the cervical spine, including zygapophyseal joints, in axial spondyloarthritis by Joan Miquel Nolla, Diego Benavent, Xavier Juanola, Xabier Michelena, Laura Berbel-Arcobé, José Antonio Narváez

“…Patients were categorised into ‘CS group’ (Bath Ankylosing Spondylitis Radiology Index ≥2 or De Vlam score ≥3 for ZJ) and ‘no CS group’ as controls. …”
Get full text

Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study by Joon Min Jung, Ye-Jee Kim, Woo Jin Lee, Chong Hyun Won, Mi Woo Lee, Sung Eun Chang

“…Patients with psoriatic disease had a significantly higher risk of Crohn’s disease [adjusted hazard ratio (aHR), 1.95; 95% confidence interval (CI) 1.42–2.67], ulcerative colitis (aHR, 1.65; 95% CI 1.39–1.96), systemic lupus erythematosus (aHR, 1.86; 95% CI 1.34–2.57), rheumatoid arthritis (aHR, 1.63; 95% CI 1.52–1.76), ankylosing spondylitis (aHR, 2.32; 95% CI 1.95–2.77), alopecia areata (aHR, 1.41; 95% CI 1.35–1.46), and type 1 diabetes (aHR, 1.23; 95% CI 1.11–1.37). …”
Get full text

Service discharges among US Army personnel with selected musculoskeletal and skin conditions: a retrospective cohort study by Michael H Weisman, D Alan Nelson, Lianne M Kurina, Robert M Kaplan

“…Objectives To determine the probability of discharge from military service among soldiers following an incident diagnosis of ankylosing spondylitis (AS), rheumatoid arthritis (RA), psoriasis or systemic lupus erythematous.Methods All soldiers on active duty in the US Army between January 2014 and June 2017 were included in a retrospective cohort analysis. …”
Get full text

Spondyloarthritis; clinical manifestations and evaluation of response to treatment in Iran by Seyed Mohammad Hashem Montazeri, Seyed Mojtaba Alavi, Fatemeh Radmard, Maryam Masoumi, Mostafa Vahedian

“…Around 66 patients (64.7%) had ankylosing spondylitis (AS), with the highest prevalence of AS. …”
Get full text

Self-evidence-based digital care programme improves health-related quality of life in adults with a variety of autoimmune diseases and long COVID: a retrospective study by Leonard Calabrese, Nicole Bundy, Mackenzie De Jesus, Millennia Lytle, Christina Gobin, Mette Dyhrberg

“…Diagnoses included: rheumatoid arthritis (20.1%); long COVID (14.9%); psoriatic arthritis (10.9%); psoriasis (8.9%); systemic lupus erythematosus (6.4%); inflammatory bowel disease (5.9%); multiple sclerosis (5.9%); ankylosing spondylitis (5.4%) and other (23.3%). On average, individuals entered observations 7.6 times/day on 86% of programme days, attended 14 coach sessions and completed the programme in an average of 17.2 weeks. …”
Get full text

Global research hotspots and trends in non-surgical treatment of adolescent idiopathic scoliosis over the past three decades: a bibliometric and visualization study by Jie Xu, Meng Chen, Xin Wang, Lin Xu, Xiaobing Luo

“…Research hotspots are adolescent idiopathic spondylitis, Schroth-based physiotherapy-specific exercise efficacy, curve development, Cobb angle, TLSO brace-based clinical efficacy, quality of life, reliability, health-related quality of life questionnaires, finite element biomechanical models, follow-up, and clinical guidelines.ConclusionThere aren't many studies that compare the clinical effectiveness of various non-surgical treatments, and because of variations in inclusion eligibility standards and outcome measures, these studies cannot be directly compared. …”
Get full text

Therapeutic potential of pupilloplasty combined with phacomulsification and intraocular lens implantation against uveitis-induced cataract by Hui Lu, Dou-Dou Chen, Si-Quan Zhu

“…Uveitis only recurred in one case with the onset of ankylosing spondylitis. HE staining showed iris stroma (all samples), pigment cell hyperplasia in pigment epithelium (n=9) and stroma (n=19), inflammatory cell infiltration in iris (n=7), and neovascularization in iris surface (n=2). …”
Get full text

The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system by Mohamed Reda Fazazi, Gian Filippo Ruda, Paul E. Brennan, Manu Rangachari

“…Finally, we provide evidence that functional inhibition of KDM5 molecules can suppress interferon (IFN)γ production from murine male effector T cells, and that an increased ratio of inflammatory Kdm6a to immunomodulatory Kdm5c transcript is observed in T helper 17 (Th17) cells from women with the autoimmune disorder ankylosing spondylitis (AS). Histone lysine demethlyases thus represent intriguing targets for the treatment of T cell-driven autoimmune disorders.…”
Get full text