Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD by Sonia Jaramillo, Lucian Le Cornet, Markus Kratzmann, Johannes Krisam, Martin Görner, Mathias Hänel, Christoph Röllig, Maxi Wass, Sebastian Scholl, Mark Ringhoffer, Alexander Reichart, Björn Steffen, Sabine Kayser, Jan-Henrik Mikesch, Kerstin Schaefer-Eckart, Jörg Schubert, Thomas Geer, Sonja Martin, Meinhard Kieser, Tim Sauer, Katharina Kriegsmann, Michael Hundemer, Hubert Serve, Martin Bornhäuser, Carsten Müller-Tidow, Richard F. Schlenk

“…Furthermore, balanced treatment groups lead to stable statistical models. However, one of the limitations of our study is the inability to adjust for unobserved or unknown confounders. …”
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A new stepwise carbon cycle data assimilation system using multiple data streams to constrain the simulated land surface carbon cycle by P. Peylin, C. Bacour, N. MacBean, S. Leonard, P. Rayner, S. Kuppel, E. Koffi, A. Kane, F. Maignan, F. Chevallier, P. Ciais, P. Prunet

“…The recent increase in the number and type of carbon cycle-related observations, including both in situ and remote sensing measurements, has opened a new road to optimize model parameters via robust statistical model–data integration techniques, in order to reduce the uncertainties of simulated carbon fluxes and stocks. …”
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Burden of disease in francophone Africa, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Charbel El Bcheraoui, PhD, Honoré Mimche, ProfPhD, Yodé Miangotar, PhD, Varsha Sarah Krish, BA, Faye Ziegeweid, MPH, Kris J Krohn, MPH, Martin Herbas Ekat, MD, Jobert Richie Nansseu, MD, Zacharie Tsala Dimbuene, PhD, Helen Elizabeth Olsen, MA, Roger C K Tine, ProfPhD, Christopher M Odell, MPP, Christopher E Troeger, MPH, Nicholas J Kassebaum, MD, Tamer Farag, PhD, Simon I Hay, ProfFMedSci, Ali H Mokdad, ProfPhD

“…GBD 2017 employed a variety of statistical models to determine the number of deaths from each cause, through the Cause of Death Ensemble model algorithm, using CoDCorrect to ensure that the number of deaths per cause did not exceed the total number of estimated deaths. …”
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Validation of gestational age determination from ultrasound or a metabolic gestational age algorithm using exact date of conception in a cohort of newborns conceived using assisted... by Steven Hawken, PhD, Brieanne Olibris, PhD, Robin Ducharme, MSc, A. Brianne Bota, PhD, Jeffrey C. Murray, MD, Beth K. Potter, PhD, Mark Walker, MD, Pranesh Chakraborty, MD, Kumanan Wilson, MD

“…We have developed and extensively validated statistical models to estimate gestational age postnatally using metabolomic markers from blood samples in combination with clinical and demographic data. …”
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Diet creates metabolic niches in the "immature gut" that shape microbial communities La dieta crea nichos metabólicos en el "intestino inmaduro" que da forma a comunidades microbia... by V. Poroyko, M. Morowitz, T. Bell, A. Ulanov, M. Wang, S. Donovan, N. Bao, S. Gu, L. Hong, J. C. Alverdy, J. Bergelson, D. C. Liu

“…Concurrently, bacterial community structure was assayed and respective representative microbiota of the groups determined by 16S rRNA gene amplicon pyrosequencing. Statistical modeling and analysis was done using SIMCA-P+ and R software. …”
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Impacto do Programa Fica Vivo na redução dos homicídios em comunidade de Belo Horizonte Impacto del Programa Permanezca Vivo en la reducción de los homicidios en comunidad de Belo... by Andréa Maria Silveira, Renato Martins Assunção, Bráulio Alves Figueiredo da Silva, Cláudio Chaves Beato Filho

“…To test the hypothesis that homicide reduction was caused by the actions implemented by the program, a statistical model was developed based on generalized linear models. …”
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The Effect of Different Levels of Foliar Application of Zinc, Iron, and Manganese Micronutrients on Reproductive Characteristics and Yield of Vitis vinifera Grapes in some Vineyard... by H. Mohebbi, A. Ebadi, M. Taheri, M. Zarabi, M.R. Bihamta

“…The analysis of each g was analyzed in the form of factorial experiment design and the effect of location factor was analyzed in the form of factorial-split (time) composite analysis in place. In the statistical model used, time and place factor considered as random and treatment was fixed.Results and Discussion Evaluation of morpho-physiological traits showed that the use of these fertilizers individually or in combination has significant positive effects on all measured traits (18 traits) at different stages of development. …”
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Effects of weaning age and weight on lamb growth rate of Morada Nova breed raised in a tropical extensive production system Efeito da idade e do peso ao desmame no ganho de peso de... by Arturo Bernardo Selaive -Villarroel, Marcus Brocardo Maciel, Nelson Manzoni de Oliveira

“…Data were analysed through a statistical model that included age and weight at weaning, sex and year of birth as fixed effects. …”
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Maternal breastfeeding: indicators and factors associated with exclusive breastfeeding in a subnormal urban cluster assisted by the Family Health Strategy by Vera A.A.L. Silva, Maria F.C. Caminha, Suzana L. Silva, Vilneide M.S.B.D. Serva, Pedro T.A.C.C. Azevedo, Malaquias Batista Filho

“…Spearman's correlation was carried out, as well as crude and adjusted prevalence ratios for a final statistical model that showed associated factors with the main outcome at a level of 0.05. …”
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Forecasting of infection prevalence of Helicobacter pylori (H. pylori) using regression analysis by Komiljon Usarov, Anvarjon Ahmedov, Mustafa Fatih Abasiyanik, Ku Muhammad Na’im Ku Khalif

“…This showed that the statistical model predicts the Hp prevalence with about 83% accuracy of the testing data set (11 months) and 87% accuracy of the training data set (42 months). …”
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Fatores ambientais e parâmetros genéticos para características produtivas e reprodutivas em um rebanho nelore no estado do Mato Grosso do Sul Study of genetic and environmental fac... by Jânio Coelho da Silveira, Concepta McManus, Arthur dos Santos Mascioli, Luiz Otávio Campos da Silva, Arley Coelho da Silveira, José Américo Soares Garcia, Helder Louvandini

“…The observations were analysed using the least squares methodology, and the statistical models included the fixed effects: year (YB) and month (MB) of calving, interaction YB*MB, sex (S) of animal (except for W18, SP18 and AFC) and calving number. …”
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Investigating the Impact of Macroeconomic Factors on the Iranian Stock Price Index by Using Averaging Methods by Saman Hatamerad, Bahram Adrangi, Hossein Asgharpur, Jafar Haghighat

“…However, this approach may overlook true uncertainty, leading to non-conservative conclusions. Statistical models comprise two parts: variables and assumptions, and the model selected based on these assumptions to estimate the variables. …”
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Are local wind power resources well estimated? by Erik Lundtang Petersen, Ib Troen, Hans E Jørgensen, Jakob Mann

“…In doing so, however, the mesoscale model output must be downscaled using some microscale physical or empirical/statistical model. That downscaling process is not straightforward, and the microscale models themselves tend to disagree in some terrain types as shown by recent blind tests [4]. …”
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Maternal breastfeeding: indicators and factors associated with exclusive breastfeeding in a subnormal urban cluster assisted by the Family Health Strategy by Vera A.A.L. Silva, Maria F.C. Caminha, Suzana L. Silva, Vilneide M.S.B.D. Serva, Pedro T.A.C.C. Azevedo, Malaquias Batista Filho

“…Spearman's correlation was carried out, as well as crude and adjusted prevalence ratios for a final statistical model that showed associated factors with the main outcome at a level of 0.05. …”
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Efecto de un Programa de actividad física sobre la autoestima en sujetos con enfermedades crónicas. Ensayo de intervención comunitaria «Pas a Pas» by Felipe Villalobos, Angels Vinuesa, Roser Pedret, Alicia Reche, Eva Domínguez, Victoria Arija

“…Results: The Program increased the PA in the IG (P = .001), while it decreased in the CG (P = .002), and also the self-esteem in the group of participants (1.28 points, P = .006) and in the groups with diagnoses of hypertension (1.60 points, P = .005), dyslipidemia (1.62 points, P = .012), excess weight (1.24 points, P = .011) or anxiety/depression (1.53 points, P = .045), assessed by multivariate statistical models. The increase in self-esteem during the intervention decreased SBP −0.5 mmHg (P = .030) in the hypertension group, regardless of baseline SBP and the effect of the intervention. …”
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Advances in Completely Automated Vowel Analysis for Sociophonetics: Using End-to-End Speech Recognition Systems With DARLA by Rolando Coto-Solano, James N. Stanford, Sravana K. Reddy

“…Our study therefore shows how technology has made progress toward greater automation in vowel sociophonetics, while also showing what remains to be done. Our statistical modeling provides a quantified view of both the abilities and the limitations of a completely “hands-free” analysis of vowel shifts in a large dataset. …”
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Identification and evaluation of managers' performance in rural development (Case study: Dolatabad rural villages of Marand County) by Aboulghasem Taghizadfanid, sajedeh dinparast, Saeid Nasire Zare, Parsa Pashaei

“…Thus, factor analysis was used as a multivariate analysis technique to evaluate the factors and to show their significance, the T-statistic model was used. ConclusionAccording to the results of the interview, 43 semantic units were obtained which after coding and classification, these criteria were classified into 26 criteria and 4 general dimensions. …”
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Produção e composição do leite de vacas de quatro grupos genéticos submetidas a dois manejos alimentares no período de lactação Production and composition of milk of cows of four g... by Liliane Cerdótes, João Restle, Dari Celestino Alves Filho, Maria de Fátima Barros Leal Nörnberg, José Laerte Nörnberg, Ivan Heck, Magali Floriano da Silveira

“…The data were submitted to variance analysis, the statistic model included management, cow genetic group, cow age and period effects and the interactions among these factors. …”
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A Review of Research Progress on Provenance Indication of Rare Earth Elements by Inductively Coupled Plasma-Mass Spectrometry Hyphenated Techniques by HAN Xiaoxiao, LIANG Tao, WANG Siyu, XIONG Zhunan, WANG Lingqing

“…The combination of highly selective separation techniques such as ion chromatography and highly sensitive ICP-MS has played an important role in the analysis of anthropogenic REEs, and the elemental speciation analysis capabilities of it make this one of the key research tools for the analysis of anthropogenic REEs.The progress of geochemical features of REEs such as isotopes in identifying material sources, resolving key processes and tracing environmental behavior, is summarized in this study, mainly including: (1)REEs fractionation patterns and isotopic features have been widely used in traditional provenance indication, and research is mainly based on REEs content or isotope information, combined with relevant mathematical and statistical models; (2) The speciation of REEs can provide an important basis for indicating anthropogenic activities, for example, due to the regional differences in the types of GBCAs used, there are obvious geographical differences in the speciation of anthropogenic REEs, with a high detection rate of macrocyclic GBCAs and a low detection rate of linear GBCAs in natural waters in regions such as Germany. …”
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Simulation of runoff from Qarahsoo basin snowmelt By Using SRM model by Mohammad Hossein Aalinejad, Saeed jahanbakhsh, Ali Mohammad Khorshiddoust

“…These CMIP5 kind models were under the control of two RCP45 and RCP85 scenarios and were downscaled with LARS-WG statistical model. Moreover, to investigate the uncertainty of models and scenarios, the best models and scenarios were selected for producing temperature and precipitation data of future periods; accordingly, the outputs of the models for future periods (2021-2040) having the basis period of (1980-2010) were compared using statistical indexes of coefficient of determination (R2) and Root Mean Square Error (RMSE). …”
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