The association between HLA DR, DQ antigens, and vulval lichen sclerosus in the UK: HLA DRB112 and its associated DRB112/DQB10301/04/09/010 haplotype confers susceptibility to vulv... by Gao, X, Barnardo, M, Winsey, S, Ahmad, T, Cook, J, Agudelo, J, Zhai, N, Powell, J, Fuggle, S, Wojnarowska, F

“…HLA DR and DQ antigens were not associated with time of onset of disease, site of involvement, structural changes of genitals, and response to treatment with potent topical steroids. In conclusion, HLA-DR and DQ antigens or their haplotypes appear to be involved in both susceptibility to and protection from LS.…”

Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition (EPIC). by Allen, N, Key, T, Dossus, L, Rinaldi, S, Cust, A, Lukanova, A, Peeters, P, Onland-Moret, N, Lahmann, P, Berrino, F, Panico, S, Larrañaga, N, Pera, G, Tormo, M, Sánchez, M, Ramón Quirós, J, Ardanaz, E, Tjønneland, A, Olsen, A, Chang-Claude, J, Linseisen, J, Schulz, M, Boeing, H, Lundin, E, Palli, D

“…We analyzed the association between prediagnostic serum concentrations of sex steroids and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition using a nested case-control design of 247 incident endometrial cancer cases and 481 controls, matched on center, menopausal status, age, variables relating to blood collection, and, for premenopausal women, phase of menstrual cycle. …”

Ankylosing spondylitis is associated with an increased risk of vertebral and nonvertebral clinical fractures: a population-based cohort study. by Muñoz-Ortego, J, Vestergaard, P, Rubio, J, Wordsworth, P, Judge, A, Javaid, M, Arden, N, Cooper, C, Díez-Pérez, A, Prieto-Alhambra, D

“…Adjustment was made for potential confounders (tobacco smoking, alcohol consumption, body mass index, and use of oral steroids). Of 4,920,353 eligible patients in SIDIAP, 6474 AS patients with matched controls (n = 32,346) were available. …”

Catalytic asymmetric carbon-carbon bond formation using alkenes as alkylmetal equivalents by Maksymowicz, R

“…</p> <p>Chapter three discusses the expansion of our method to the 1,4- and 1,6-addition to complex steroids. Modified conditions were then found to enable the addition to β-substituted enones, to form quaternary centres. …”

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. by Freel, E, Ingram, M, Friel, E, Fraser, R, Brown, M, Samani, N, Caulfield, M, Munroe, P, Farrall, M, Webster, J, Clayton, D, Dominiczak, A, Davies, E, Connell, J

“…METHODS: The CYP11B2-344 C/T polymorphism was genotyped and urinary excretion of adrenal steroid metabolites was measured (by GCMS) in 511 unrelated hypertensives from the Medical Research Council (MRC) British Genetics of Hypertension (BRIGHT) study. …”

Plasma metabolomics implicates modified transfer RNAs and altered bioenergetics in the outcomes of pulmonary arterial hypertension by Rhodes, CJ, Ghataorhe, P, Wharton, J, Rue-Albrecht, KC, Hadinnapola, C, Watson, G, Bleda, M, Haimel, M, Coghlan, G, Corris, PA, Howard, LS, Kiely, DG, Peacock, AJ, Pepke-Zaba, J, Toshner, MR, Wort, SJ, Gibbs, JSR, Lawrie, A, Gräf, S, Morrell, NW, Wilkins, MR

“…Increased levels of tRNA-specific modified nucleosides (N2,N2-dimethylguanosine, N1-methylinosine), tricarboxylic acid cycle intermediates (malate, fumarate), glutamate, fatty acid acylcarnitines, tryptophan, and polyamine metabolites and decreased levels of steroids, sphingomyelins, and phosphatidylcholines distinguished patients from control subjects. …”

Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo. by Hughes, K, Manolopoulos, K, Iqbal, J, Cruden, N, Stimson, R, Reynolds, R, Newby, D, Andrew, R, Karpe, F, Walker, B

“…We used stable isotope tracers to test the hypothesis that both 11βHSD1-reductase and -dehydrogenase activities occur in human metabolic tissues in vivo. 1,2-[(2)H](2)-Cortisone (d2-cortisone) was validated as a tracer for 11β-dehydrogenase activity and its inhibition by licorice. d2-Cortisone and 9,11,12,12-[(2)H](4)-cortisol (d4-cortisol) (to measure 11β-reductase activity) were coinfused and venous samples obtained from skeletal muscle, subcutaneous adipose (n = 6), and liver (n = 4). Steroids were measured by liquid chromatography-tandem mass spectrometry and arteriovenous differences adjusted for blood flow. …”

Hospital-acquired Colonization and Infections in a Vietnamese Intensive Care Unit by Duong, T

“…Significant risk factors for AROs colonization were chronic liveriver disease, chronic lung disease, chronic kidney disease, steroids use, ICU admission for non-infectious diseases, and receipt of antimicrobial treatment on ICU admission. …”

Prescription of oral short-acting beta 2-agonist for asthma in non-resource poor settings: A national study in Malaysia by Chin, M.C., Sivasampu, S., Khoo, E.M.

“…The rate of oral SABA, oral steroids, inhaled SABA and inhaled corticosteroids prescriptions were 33, 33, 50 and 23 per 100 asthma encounters, respectively. …”

Preliminary phytochemical study and antimicrobial activity from various extract of Cynodon dactylon (L.) Pers. (Bermuda) against selected pathogens by Syahriel Abdullah, Januarius Gobilik, Chong, Khim Phin

“…Phytochemical studies confirmed the plant contains many bioactive compounds such as alkaloids, cardiac glycosides, terpenoids and steroids, saponins, phenolic compounds, flavonoids, tannins, carbohydrates and proteins. …”
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Eleusine indica for food and medicine by Zikry Hamizan Md Zakri, Monica Suleiman, Ng, Shean Yeaw, Zainab Ngaini, Salahaudin Maili, Fatimah Salim

“…It represents a rich source of nutrients and contains therapeutic phytochemicals such as flavonoids, steroids, essential oils, cardiac glycosides, coumarins, fatty acids, anthraquinones, anthrones, triterpenes, tannins, and alkaloids. …”
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Hepatoprotective Potential of Malaysian Medicinal Plants: A Review on Phytochemicals, Oxidative Stress, and Antioxidant Mechanisms by Balu Alagar Venmathi Maran, Mohammad Iqbal, Prakash Gangadaran, Ahn, Byeong-Cheol, Pasupuleti Visweswara Rao, Muhammad Dawood Shah

“…Moreover, these plants have been shown to play a vital role in ameliorating cellular damage because they contain several phytochemicals, including alkaloids, saponins, flavonoids, tannins, terpenoids, steroids, polyphenols, and diterpenoid lactones. The following antioxidant, anti-inflammatory, immunomodulatory, and hepatoprotective compounds have been found in these plants: andrographolide, rosmarinic acid, phenol, eugenol, 9,12-octadecadienoic, n-hexadecanoic acid, dihydroxy dimethoxy flavone, sitosterol, demethoxycurcumin, quercetin, linoleic acid, stigmasterol, kojic acid, indole-2-one, α-terpinol, linalool, kaempferol, catechin, ellagic acid, and oleanolic acid. …”
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Phytochemical and Antibacterial Effects of Leaf Extract from Mangrove Plant (Avicennia Marina) on Vibrio Parahaemolyticus in Shrimps by Azis, Gazali Salim, Agus Indarjo, Lukman Yudho Prakoso, Retno Hartati, Achmad Daengs GS, Meiryani, La Ode Muhammad Aslan, Julian Ransangan, Rozi

“…The results from the phytochemical analysis demonstrated that the ethanolic extract from the mangrove plant contained varying amounts of flavonoids, tannins, saponins, polyphenols, alkaloids, steroids, and triterpenoids. However, the number of flavonoids and alkaloids seemed to be higher than the other metabolites. …”
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Immunodiagnosis and vaccination for brugian filariasis: direct rewards from research investments by Abdullah, Wan Omar

“…Filaricidal drugs unfortunately has no effect on the main pathological consequence of repeated infection, namely elephantiasis, for which in fact no drug treatment has any effect except possibly steroids in early cases. At Universiti Putra Malaysia, small scale preliminary studies into herbal remedy for chronic elephantiasis has been conducted and has shown encouraging results. …”
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Effect of kenaf seed oil from different ways of extraction towards ovarian cancer cells. by Saiful Yazan , Latifah, Foo, Jhi Bhiau, Abd Ghafar, Siti Aisyah, Chan, Kim Wei, Md. Tahir, Paridah, Ismail, Maznah

“…Kenaf is composed of various active components including tannins, saponins, polyphenolics, alkaloids, essential oils and steroids. It has been used to treat bruises, bilious conditions, fever and puerperium. …”
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Natural compounds extracted from Moringa oleifera and their agricultural applications by Ahmad, Khairulmazmi, Adam, Tijjani

“…M. oleifera is a medicinal plant that synthesizes such metabolites which include phenolic acids, carotenoids, quinones, antraquinones, flavonoids, flavonols, flavones, tannins, alkaloids, coumarins, terpenoids, amines, cyanogenic glycosides, triterpenoids, non-protein amino acids, glucosinolates, polyacetylenes, polyketides, phenylpropanes, steroids and saponins. They exert biological activities and can potentially be used to retard microbial activities. …”
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Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections by Nordin, Nornasriq Akmal, Mohd Zin, Nur Bainun, Fazilah, Nurul Farhana, Wasoh, Helmi, Ariff, Arbakariya, Halim, Murni

“…The in-vitro qualitative assays showed that both S. alata and S. tora leaf extracts contained bioactive and secondary metabolites components such as tannins, steroids, saponin, terpenoids, glycosides, flavonoids and phenols. …”
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Phytochemical screening and characterization of Meliadubia leaves extract for antimicrobial activity against Escherichia coli staphylococcus and aureus by Mustafa, Mudhafar, Ismail, Zainol, Jaafar, C. N. Aiza, H. A., Alsailawi, Arkan, Majhool Alhussein, M. B., Alsaady Mofaq

“…Phytochemical screening analysis was done using common procedures and had shown the presence of alkaloids, carbohydrates, tannins, steroids, and flavonoids. Twenty-two compounds were identified in the GC-Mass spectrometry. …”

Impact of Sex and Menopausal Status on Episodic Memory Circuitry in Early Midlife by Jacobs, E. G., Weiss, B. K., Makris, N., Buka, S. L., Klibanski, A., Goldstein, J. M., Whitfield-Gabrieli, Susan

“…Across women, lower 17β-estradiol concentrations were related to more pronounced alterations in hippocampal connectivity and poorer performance on a subsequent memory retrieval task, strongly implicating sex steroids in the regulation of this circuitry. Finally, subgroup analyses revealed that high-performing postmenopausal women (relative to low and middle performers) exhibited a pattern of brain activity akin to premenopausal women. …”
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Biomarker stratigraphy in the Athel Trough of the South Oman Salt Basin at the Ediacaran‐Cambrian Boundary by Roussel, Anaïs, Cui, Xingqian, Summons, Roger E

“…Here, we present a comprehensive study of biomarker hydrocarbons, including steroids, triterpenoids, and carotenoids. Among the compounds detected is a distinctive array of aromatic carotenoids. …”
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