Pulmonary manifestations of childhood-onset primary Sjogren’s syndrome (SS) masquerading as reactive airways disease in a male patient and review of interstitial lung disease assoc... by Adam Bartholomeo, Shean Aujla, Meryle Eklund, Cheryl Kerrigan, Ellen Riemer, Mileka Gilbert

“…Abstract Background Sjogren’s syndrome (SS) is a rare chronic autoimmune disease involving exocrine glands presenting with sicca syndrome, recurrent parotitis and other extraglandular stigmata. SS is well characterized in the adult population with classification criteria; however, primary SS presenting in childhood is poorly defined and rare in males. …”
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Mucosal Healing in Celiac Disease: Villous Architecture and Immunohistochemical Features in Children on a Long-Term Gluten Free Diet by Roberta Mandile, Mariantonia Maglio, Caterina Mosca, Antonella Marano, Valentina Discepolo, Riccardo Troncone, Renata Auricchio

“…In conclusion, a GFD is able to both restore a normal V/C ratio and reduce inflammation, but the epithelium maintains some stigmata of the disorder, such as an increased number of CD3+ and TCRγδ+ cells. …”
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Comparison of Preoperative Evaluation with the Pathological Report in Intraductal Papillary Mucinous Neoplasms: A Single-Center Experience by Vladimir Djordjevic, Nikica Grubor, Jelena Djokic Kovac, Marjan Micev, Natasa Milic, Djordje Knezevic, Pavle Gregoric, Zeljko Lausevic, Mirko Kerkez, Srbislav Knezevic, Dejan Radenkovic

“…All the patients diagnosed with IPMNs were stratified concerning the presence of the absolute and relative indications according to EEBGPCN and high-risk stigmata and worrisome features according to FCG. Final histopathology revealed that IPMNs patients were further divided into malignant (50 patients) and benign (18 patients) groups, according to the pathological findings. …”
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Engineered <i>Lactobacillus paracasei</i> Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice by Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Jie Lu, Chiara Corpetti, Alessandro Del Re, Fatima Domenica Elisa De Palma, Giovanni Esposito, Walter Sanseverino, Giovanni Sarnelli

“…Being a key member of the larger family of bioactive autacoid local injury antagonist amides (ALIAmides), PEA significantly improves the clinical and histopathological stigmata in models of ulcerative colitis (UC). Despite its safety profile, high PEA doses are required in vivo to exert its therapeutic activity; therefore, PEA has been tested only in animals or human biopsy samples, to date. …”
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Evaluation of liver diseases in Iranian patients with primary antibody deficiencies by Farzaneh Motamed, Asghar Aghamohammadi, Mahmoud Soltani, Mahboubeh Mansouri, Nima Rezaei, Shahram Teimourian, Nima Pouladi, Sina Abdollahzadeh, Nima Parvaneh

“…Only one patient was HCV-RNA positive; he had stigmata of chronic liver disease and pathologic evidence of chronic active hepatitis with cirrhosis. …”
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Ūmino nevarikozinio kraujavimo įvertinimo ir stabdymo protokolas by Jonas Valantinas

“…Proton pomp inhibitors therapy is useful only in a selected group of patients, namely those with ulcers having endoscopic high risk stigmata of rebleeding (nonbleeding visible vessel, adherent clot or active bleeding at the time of endoscopy). …”
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Genetic Testing for Supravalvar Aortic Stenosis: What to Do When It Is Not Williams Syndrome by Sara B. Stephens, Tyler Novy, Gabrielle N. Spurzem, Benjamin Jacob, Taylor Beecroft, Emily Soludczyk, Beth A. Kozel, Justin Weigand, Shaine A. Morris

“…Hypercholesterolemia can also be considered in individuals bearing the stigmata of this disease.…”
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Creating an Intercultural User-Centric Design for a Digital Sexual Health Education App for Young Women in Resource-Poor Regions of Kenya: Qualitative Self-Extended Double Diamond... by Clarissa Soehnchen, Annika Rietz, Vera Weirauch, Sven Meister, Maike Henningsen

“…ConclusionsThe developed intercultural research model provides an impetus to providing digital sexual health education, integrating culture-specific aspects in the design process, while focusing on cultural and religious stigmata. The reusable framework enables identifying and overcoming hurdles in providing information about taboo and intimate topics. …”
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Relapsed nodular lymphocyte-predominant Hodgkin lymphoma presenting as severe paraneoplastic hepatitis: a case report by Anthony J. Deacon, Naeman N. Goetz, Nicholas Weber, Andrew Clouston, Enoka Gonsalkorala, Catherine Baskerville, Barbara Leggett

“…On physical examination, there was scleral icterus and ecchymoses, but no evidence of hepatic encephalopathy, other stigmata of chronic liver disease, or lymphadenopathy. …”
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Humoral Predictors of Malignancy in IPMN: A Review of the Literature by Enrico C. Nista, Tommaso Schepis, Marcello Candelli, Lucia Giuli, Giulia Pignataro, Francesco Franceschi, Antonio Gasbarrini, Veronica Ojetti

“…Jaundice, enhancing mural nodule >5 mm, main pancreatic duct diameter >10 mm, and positive cytology for high-grade dysplasia are considered high-risk stigmata of malignancy. While increased levels of carbohydrate antigen 19-9 (CA 19-9) (>37 U/mL), main pancreatic duct diameter 5–9.9 mm, cyst diameter >40 mm, enhancing mural nodules <5 mm, IPMN-induced acute pancreatitis, new onset of diabetes, cyst grow-rate >5 mm/year are considered worrisome features of malignancy. …”
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Ten years review of Hepatocellular carcinoma In Hospital Universiti Sains Malaysia (1996-2005) by Aman, Ab. Latif

“…The clinical presentations included abdominal discomfort in 98(90.7%), abdominal pain in 55(50.9%), abdominal distension in 68(62.7%), loss of weight in 62(57.4%), stigmata of chronicliver disease in 51(47.2%) and jaundice in 52(48.1 %) patients. …”
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Association between Diffusion Tensor Imaging, inflammation and immunological alterations in unipolar and bipolar depression: a review by R. Aronica, P. Enrico, P. Brambilla, G. Delvecchio

“…Neuropathology of mood disorders: do we see the stigmata of inflammation? Transl Psychiatry. 2016;6(11):e946), recent studies have demonstrated how white matter (WM) microstructural impairments detected by Diffusion Tensor Imaging (DTI) are correlated to peripheral immunomarkers in depressed patients. …”
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The Benefit of a Retrospective Pregnancy Anamnesis in Child and Adolescent Psychiatry: The Reliability of Maternal Self-Report during Childhood Development by Stefan Mestermann, Peter A. Fasching, Matthias W. Beckmann, Jennifer Gerlach, Oliver Kratz, Gunther H. Moll, Johannes Kornhuber, Anna Eichler, the IMAC-Mind-Consortium

“…Thought to be due to social stigmata and memory effects, pregnancy self-reports cannot be precisely reproduced. …”
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Threshold of main pancreatic duct for malignancy in intraductal papillary mucinous neoplasm at head-neck and body-tail by Hao Zhou, Xiaoshuang Li, Yajie Wang, Zhiyue Wang, Jingrong Zhu, Zhongqiu Wang, Xiao Chen

“…Abstract Background Main pancreatic duct (MPD) dilation is a high-risk stigmata/worrisome feature of malignancy in intraductal papillary mucinous neoplasms (IPMNs). …”
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The Slavcleft: a three-center study of the outcome of treatment of cleft lip and palate. Nasolabial appearance by Adam Stebel, Wanda Urbanová, Irena Klimova, Andrzej Brudnicki, Ivana Dubovska, Petra Polackova, Daniela Kroupová, Magdalena Koťová, Piotr S. Fudalej

“…Despite, facial appearance in subjects with CLP is rarely ideal and residual stigmata are easy to notice in many patients irrespective of the protocol. …”
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Efficacy and Safety of Pancreatic Juice Cytology with Synthetic Secretin in Diagnosing Malignant Intraductal Papillary Mucinous Neoplasms of the Pancreas by Yohei Takeda, Kazuya Matsumoto, Takumi Onoyama, Taro Yamashita, Hiroki Koda, Wataru Hamamoto, Yuri Sakamoto, Takuya Shimosaka, Shiho Kawahara, Yasushi Horie, Hajime Isomoto

“…The risk classifications based on the 2017 international consensus guidelines were high-risk stigmata, worrisome features, and no risk in 29, 59, and 45 patients, respectively. …”
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Non-invasive diagnosis of liver fibrosis in children with chronic hepatitis B by transient elastography by Sayma Rahman Munmun, Mohammad Rukunuzzaman, Mohammad Wahiduzzaman Mazumder, Archana Shrestha Yadav, Luthfun Nahar, Mohammad Benzamin, Abu Sayed Mohammad Bazlul Karim

“…Findings of transient elastography were significantly associated with clinical findings like anaemia, jaundice, hepatosplenomegaly, stigmata of CLD and biochemical findings like  serum ALT, AST as well as  virological parameters. …”
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Syphilis - a disease that still occurs by Rami Ben Rhaiem, Przemysław Kępka, Daria Kuziemkowska, Jan Kuźma, Anna Łącka-Majcher, Aleksandra Łokczewska-Bojar, Grzegorz Tarsa, Magdalena Skotalczyk, Zuzanna Sawińska, Katarzyna Sudelska

“…Congenital syphilis has also been divided into early (which includes the first 2 years) as well as late, which is characterised by signs of congenital syphilis, the so-called stigmata of congenital syphilis constituting the untreated infection during the fetal stage or the infancy stage.  …”
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The impact of self-stigma in people with diagnosis of severe mental illness: a cross-sectional pilot study from a community psychiatry unit in Porto, Portugal by A. S. Pinto, M. Almada, I. Fonseca, A. Sousa, A. Lopes

“…Severe mental illness is one of the most socially exclusive stigmata and is associated with poor clinical and functional outcomes and social withdrawal. …”
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Fatty Acid Amide Hydrolase Deficiency Is Associated with Deleterious Cardiac Effects after Myocardial Ischemia and Reperfusion in Mice by Sanela Rajlic, Luise Surmann, Pia Zimmermann, Christina Katharina Weisheit, Laura Bindila, Hendrik Treede, Markus Velten, Andreas Daiber, Georg Daniel Duerr

“…Interestingly, FAAH^−/− mice showed stigmata such as enhanced inflammation, cardiomyocyte loss, stronger remodeling, and persistent scar with deteriorated LV function compared to wild-type (WT) littermates. …”
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