Exploratory imaging outcomes of a phase 1b/2a clinical trial of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: Structural effects and functional connectivi... by Adam C. Raikes, Gerson D. Hernandez, Dawn C. Matthews, Ana S. Lukic, Meng Law, Yonggang Shi, Lon S. Schneider, Roberta D. Brinton

“…Consistent with structural changes, ALLO strengthened local, inter‐regional, and network level functional connectivity in AD‐vulnerable regions, including the precuneus and posterior cingulate, and network connections between the default mode network and limbic system. …”
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Development of a Quality Management Model and Self-assessment Questionnaire for Hybrid Health Care: Concept Mapping Study by Rosian Tossaint-Schoenmakers, Marise J Kasteleyn, Anneloek Rauwerdink, Niels Chavannes, Sofie Willems, Esther P W A Talboom-Kamp

“… BackgroundWorking with eHealth requires health care organizations to make structural changes in the way they work. Organizational structure and process must be adjusted to provide high-quality care. …”
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Relationship between kidney ultrasound data and blood creatinine and urea levels in cats with autosomal dominant polycystic kidney disease by D. Kibkalo, O. Tymoshenko, O. Siehodin, O. Tsymerman, O. Matsenko

“…The results of studying the influence of structural changes in the kidneys on their filtration in cats with polycystic kidney disease are given. …”
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Effect of Double Mutation (L452R and E484Q) on the Binding Affinity of Monoclonal Antibodies (mAbs) against the RBD—A Target for Vaccine Development by Deepali Gupta, Mukesh Kumar, Priyanka Sharma, Trishala Mohan, Amresh Prakash, Renu Kumari, Punit Kaur

“…The results obtained from our study suggest that the structural and dynamic changes introduced by these co-mutations reduce the binding affinity of the viral S protein to monoclonal antibodies (mAbs). The structural changes imposed by L452R create a charged patch near the interfacial surface that alters the affinity towards mAbs. …”
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Are public health researchers designing for dissemination? Findings from a national survey in China by Yiluan Hu, Xuejun Yin, Enying Gong, Jing Liu, Xia Liu, Ruitai Shao, Juan Zhang, Ross C Brownson

“…Our findings have implications for structural changes in academic incentive systems, collaborations and partnerships, funding priorities, and training opportunities.…”
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Transcription factors MhyFIL1 and MhyFIL3 <i>(Monotropa hypopitys)</i> determine the asymmetric development of above-ground lateral organs in plants by A. V. Shchennikova, A. M. Kamionskaya, A. V. Nezhdanova, K. S. Gavrilova, M. A. Filyushin, E. Z. Kochieva, K. G. Skryabin

“…Thus, the absence of structural changes from the M. hypopitys flower in comparison to autotrophic species and the effect of MhyFIL1/3 heterologous expression on the development of tobacco plants indicate the preservation of the functions of the vegetative YABBY genes by the MhyFIL1/3 genes in pinesap. …”
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Methods and approaches of determining the boundaries of agglomerations (basic case Kharkiv region) by Kateryna Kravchenko, Kostiantyn Niemets, Kateryna Sehida, Lyudmyla Niemets, Olha Suptelo

“…Changes in social relations in Ukraine, its transition to a post-industrial society, structural changes in regional development lead in modern conditions to changes in the territorial organization of society, which directly affects the trends of regional development. …”
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Synthesis and characterization of lanthanum- and yttrium-doped Fe2O3 pigments Síntese e caracterização de pigmentos de Fe2O3 dopados com lantânio e ítrio by D. M. A. Melo, M. A .F. Melo, A. E. Martinelli, Z. R. Silva, J. D. Cunha, A. C. Lima

“…The values of the colorimetric coordinates in this case varied from L* a* b* = 45.230, 17.315, 28.750 to L* a* b* =51.631, 15.726, 25.825. Structural changes were also noticed as a function of the size of the rare earth ion added to the structure. …”
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Economic growth factors system: theoretical and methodological aspect by H.Ya. Hlukha

“…They function through structural changes, distribution and motivation system, insignificant restrictions and stimulus. …”
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Discontinuity in the Electronic Structure and Magnetic Order of <i>β</i>-Co_1+<i>x</i>Ga_1−<i>x</i> by Gerhard H. Fecher

“…For <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>x</mi><mo>≳</mo><mn>0.6</mn></mrow></semantics></math></inline-formula>, the structure changes to a face-centered cubic structure with random site occupation and the magnetic moment further increases. …”
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Ca²⁺/Sr²⁺ Selectivity in Calcium-Sensing Receptor (CaSR): Implications for Strontium’s Anti-Osteoporosis Effect by Diana Cheshmedzhieva, Sonia Ilieva, Eugene A. Permyakov, Sergei E. Permyakov, Todor Dudev

“…The binding of the native agonist (Ca²⁺) to CaSR activates the receptor, which undergoes structural changes that trigger a cascade of events along the cellular signaling pathways. …”
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In Silico Evaluation of Coding and Non-Coding nsSNPs in the Thrombopoietin Receptor (<i>MPL</i>) Proto-Oncogene: Assessing Their Influence on Protein Stability, Structure, and Func... by Hakeemah H. Al-nakhle, Hind S. Yagoub, Sadin H. Anbarkhan, Ghadah A. Alamri, Norah M. Alsubaie

“…Non-synonymous single nucleotide polymorphisms (nsSNPs) in <i>MPL</i> have the potential to disrupt normal protein function, prompting our investigation into the most deleterious <i>MPL</i> SNPs and the associated structural changes affecting protein–protein interactions. …”
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Effects of Dietary Fish Meal Replacement with Composite Mixture of Chicken Meal, Krill Meal, and Plant Proteins on Growth, Physiological Metabolism, and Intestinal Microbiota of Ch... by Liyun Ding, Jiacheng Chen, Yanping Zhang, Jun Xiao, Xiandong Xu, Haixing Zhang, Qingtang Chen, Yuxiang Zhao, Wenjing Chen

“…The microbial community structure changed significantly. Mycoplasma showed the highest abundance in the D1 and D2 groups (P<0.05), and Cetobacterium peaked in D2 group, and significantly higher than that in D1 group (P<0.05). …”
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Ultrastructural changes in esophageal tissue undergoing stretch tests with possible impact on tissue engineering and long gap esophageal repairs performed under tension by Ede Biro, Gerhard Sommer, Gerd Leitinger, Hajnalka Abraham, Daniel J. Kardos, Zsolt Oberritter, Amulya K. Saxena

“…Abstract Esophageal biomechanical studies are being performed to understand structural changes resulting from stretches during repair of esophageal atresias as well as to obtain biomechanical values for tissue-engineered esophagus. …”
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Right ventricular assessment of the adolescent footballer’s heart by D. X. Augustine, J. Willis, S. Sivalokanathan, C. Wild, A. Sharma, A. Zaidi, K. Pearce, G. Stuart, M. Papadakis, S. Sharma, A. Malhotra

“…Abstract Introduction Athletic training can result in electrical and structural changes of the right ventricle that may mimic phenotypical features of arrhythmogenic right ventricular cardiomyopathy (ARVC), such as T-wave inversion and right heart dilatation. …”
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Dinuclear Silver(I) Nitrate Complexes with Bridging Bisphosphinomethanes: Argentophilicity and Luminescence by Kristina F. Baranova, Aleksei A. Titov, Oleg A. Filippov, Alexander F. Smol’yakov, Alexey A. Averin, Elena S. Shubina

“…The contribution of Ag atoms to the excited state in both complexes <b>2a</b> and <b>2b</b> decreased relative to <b>1</b> in agreement with the structural changes caused by pyrazole coordination.…”
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Gyrification patterns in first-episode, drug-naïve major depression: Associations with plasma levels of brain-derived neurotrophic factor and psychiatric symptoms by Tomoya Natsuyama, Naomichi Okamoto, Keita Watanabe, Enkhmurun Chibaatar, Hirofumi Tesen, Gaku Hayasaki, Atsuko Ikenouchi, Atsuko Ikenouchi, Shingo Kakeda, Reiji Yoshimura

“…Background and objectivesCortical structural changes in major depressive disorder (MDD) are usually studied using a voxel-based morphometry approach to delineate the cortical gray matter volume. …”
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Hierarchical Urban Land Mappings and Their Distribution with Physical Medium Environments Using Time Series of Land Resource Images in Beijing, China (1981–2021) by Tao Pan, Wenhui Kuang, Ruoyi Pan, Zhenguo Niu, Yinyin Dou

“…Rapid urban expansion and structural changes are taking place in China’s capital city, Beijing, but without an update of urban land features in a timely manner our understanding of the new urban heterogeneity is restricted, as land-background data is indispensable for bio-geophysical and bio-geochemical processes. …”
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Cytokines, insulin resistance and arterial wall stiffness in assessing the course of non-alcoholic fatty liver disease by Yu. M. Stepanov, V. I. Didenko, O. M. Tatarchuk, I. S. Konenko, O. P. Petishko

“…The level of TNF-α increased with the progression of structural changes in the liver and at grade 4 of steatosis its content was increased by 6.4 times (P < 0.05) relative to the level in the control group, by 8.0 times (P < 0.05) relative to group I patients, by 3.4 times (P < 0.05) – group II patients and by 1.8 times (P < 0.05) – group III patients. …”
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Neuroplasticity of the Lateral Geniculate Nucleus in Response to Retinal Gene Therapy in a Group of Patients with RPE65 Mutations by Ashtari M, Lipin M, Duong M, Ying GS, Yu Y, Maguire A, Bennett J

“…The exact trajectory of the structural changes taking place in LGN is unclear but our data shows that even after years of low vision, the LGN in RPE65 patients has the potential for plasticity and expansion to a nearly normal volume one year after gene therapy administration.Keywords: brain plasticity, retinal gene therapy, lateral geniculate nucleus, image processing, brain morphometry…”
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