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2501
Cancer Stem-Like Phenotype of Mitochondria Dysfunctional Hep3B Hepatocellular Carcinoma Cell Line
Published 2021-06-01“…Additionally, the Hep3B/ρ<sup>0</sup> cells showed resistance to the anticancer drug doxorubicin because of the increased expression of ATP-binding cassette Subfamily B Member 1. The Hep3B/ρ<sup>0</sup> conditioned medium induced more and thicker blood vessels and increased the mobility and invasiveness of the blood vessel cells. …”
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2502
Genome-wide identification of the trehalose-6-phosphate synthase gene family in sweet orange (Citrus sinensis) and expression analysis in response to phytohormones and abiotic stre...
Published 2022-09-01“…The phylogenetic tree showed that CisTPS genes were divided into two subfamilies, and genes in each subfamily had conserved intron structures and motif compositions. …”
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2503
The earliest dipodomyine heteromyid in North America and the phylogenetic relationships of geomorph rodents
Published 2023-03-01“…Here, a new genus and species of a large dipodomyine is reported from early Miocene-aged deposits of the John Day Formation in Oregon that represents the earliest record of the subfamily. The taxon is known from a single specimen consisting of a nearly complete skull, dentary, partial pes, and caudal vertebra. …”
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2504
Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer
Published 2021-05-01“…L1 transposons occupy 17% of the human genome and are widely exapted for the regulation of human genes, particularly in breast cancer, where we have previously shown abundant cancer-specific transcription factor (TF) binding sites within the L1PA2 subfamily. In the current study, we performed a comprehensive analysis of TF binding activities in primate-specific L1 subfamilies and identified pervasive exaptation events amongst these evolutionarily related L1 transposons. …”
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2505
Prediction of Hepatic Clearance of Stereoselective Metabolism of Carvedilol in Liver Microsomes and Hepatocytes of Sprague-Dawley and Cytochrome P450 2D-Deficient Dark Agouti Rats
Published 2019-01-01“…Hepatic clearance (CLh) of carvedilol (CAR), which is eliminated via stereoselective metabolism by the CYP2D subfamily of cytochromes P450 (CYPs), was predicted using liver microsomes and hepatocytes from Sprague-Dawley (SD) rats and CYP2D-deficient Dark Agouti (DA) rats to determine the usefulness of prediction method. …”
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2506
Insights into the Relationship between Pentraxin-3 and Cancer
Published 2022-12-01“…PTX-3 is a member of the long pentraxin subfamily which plays an important role in regulating inflammation, innate immunity response, angiogenesis, and tissue remodeling. …”
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2507
Genomic Data Mining Reveals Abundant Uncharacterized Transporters in <i>Coccidioides immitis</i> and <i>Coccidioides posadasii</i>
Published 2022-10-01“…They were further annotated to class, subclass, family, subfamily and range of substrates based on the Transport Classification (TC) system. …”
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2508
Effects of Temperatures and Rainfall Variability on the Abundance and Diversity of Caelifera (Insecta, Orthoptera) in Three Natural Environments in the Mzab Valley, Septentrional S...
Published 2018-12-01“…A total of 22 grasshopper species were collected, representing four families and eight subfamilies. The subfamily Oedipodinae was the dominant, followed by Pyrgomorphinae and Thrinchinae. …”
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2509
Genome-wide identification and expression analysis of ARF gene family in embryonic development of Korean pine (Pinus koraiensis)
Published 2024-04-01“…A phylogenetic analysis revealed that these 13 PkorARF genes can be classified into 4 subfamilies, indicating the presence of conserved structural characteristics within each subfamily. …”
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2510
Pollen Morphological Peculiarities of Selected Mimosoideae Taxa of Hainan Island and Their Taxonomic Relevance
Published 2022-05-01“…Mimosoideae is one of the taxonomically complex subfamilies of Fabaceae. Several studies have reported the pollen morphology of Mimosoideae taxa and their taxonomic relevance, but no such study was found specifically for Hainan Island in southern China. …”
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2511
Thermosensory Transient Receptor Potential Ion Channels and Asthma
Published 2021-07-01“…The reception of physical and chemical environmental stimuli and the regulation of body temperature are mediated by thermosensory channels, members of a subfamily of transient receptor potential (TRP) ion channels. …”
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2512
Mouse B2 SINE elements function as IFN-inducible enhancers
Published 2023-05-01“…Here, we investigated the mouse epigenomic response to type II interferon (IFN) signaling and discovered that elements from a subfamily of B2 SINE (B2_Mm2) contain STAT1 binding sites and function as IFN-inducible enhancers. …”
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2513
Assessment of ITS2 Region Relevance for Taxa Discrimination and Phylogenetic Inference among Pinaceae
Published 2022-04-01“…A total of 368 sequences representing 71 closely and distantly related taxa of the seven genera and three subfamilies of Pinaceae were characterized for genetic variability and divergence. …”
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2514
Detection of anti-Leishmania spp. antibodies in poultry from central region of Rio Grande do Sul, Brazil
Published 2023-12-01“…In addition, the blood of these animals is a preferred food source for insects of the subfamily Phlebotominae, which can be used them as bioindicators of the presence of these phlebotomes.…”
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2515
Kv10.1 Regulates Microtubule Dynamics during Mitosis
Published 2020-08-01“…Kv10.1 (potassium voltage-gated channel subfamily H member 1, known as EAG1 or Ether-à-go-go 1), is a voltage-gated potassium channel, prevailingly expressed in the central nervous system. …”
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2516
1,6-Naphthyridin-2(1<i>H</i>)-ones: Synthesis and Biomedical Applications
Published 2021-10-01“…Among such structures, 1,6-naphthyridin-2(1<i>H</i>)-ones (<b>7</b>) are a subfamily that includes more than 17,000 compounds (with a single or double bond between C3 and C4) included in more than 1000 references (most of them patents). …”
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2517
WRKY transcription factor family in lettuce plant (Lactuca sativa): Genome-wide characterization, chromosome location, phylogeny structures, and expression patterns
Published 2022-10-01“…Interaction network analysis indicated that LsWRKY TFs could interact with other proteins, such as SIB (sigma factor binding protein), WRKY TFs, and MPK. The WRKYIII subfamily genes showed different expression patterns during the progress of asparagus lettuce stem enlargement. …”
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2518
Bipartite genome and structural organization of the parvovirus Acheta domesticus segmented densovirus
Published 2023-06-01“…Its vp segment acquired a phospholipase A2-encoding gene, vpORF3, via inter-subfamily recombination, coding for a non-structural protein. …”
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2519
Comparative Morphology, Phylogeny, Classification and Evolution of Interstitial Habits in Microcambevine Catfishes (Siluriformes: Trichomycteridae)
Published 2021-11-01“…The Microcambevinae are a catfish subfamily endemic to the Brazilian Atlantic Forest, comprising rare species with interstitial habits. …”
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2520
Functions and mechanisms of protein disulfide isomerase family in cancer emergence
Published 2022-08-01“…Herein, we review recent research advances on PDIs, vis-à-vis their expression, functions, and molecular mechanisms in supporting cancer growth with special emphasis on the anterior gradient (AGR) subfamily. Last, we posit the relevance and therapeutic strategies in targeting the PDIs in cancer.…”
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