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RESTRICTED FEEDING SCHEDULES MODULATE IN A DIFFERENT MANNER THE EXPRESSION OF CLOCK GENES IN RAT HYPOTHALAMIC NUCLEI.
Published 2016-12-01“…We hypothesized that different feeding restriction patterns could modulate the expression of clock genes in the suprachiasmatic nucleus (SCN) master clock and in extra-SCN oscillators such as the paraventricular (PVN) and arcuate (ARC) hypothalamic nuclei. …”
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242
Role of Dorsomedial Hypothalamus GABAergic Neurons in Sleep–Wake States in Response to Changes in Ambient Temperature in Mice
Published 2022-01-01“…It also receives projection from the preoptic area, which is an important region for sleep and energy homeostasis and the suprachiasmatic nucleus—a main control area of the clock rhythm. …”
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243
Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription
Published 2011“…The Rasd1 protein is a dexamethasone induced monomeric Ras-like G protein that oscillates in the suprachiasmatic nucleus (SCN). Previous studies have shown that Rasd1 modulates multiple signaling cascades. …”
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244
Redox and Antioxidant Modulation of Circadian Rhythms: Effects of Nitroxyl, N-Acetylcysteine and Glutathione
Published 2021-04-01“…The circadian clock at the hypothalamic suprachiasmatic nucleus (SCN) entrains output rhythms to 24-h light cycles. …”
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245
Time-restricted feeding entrains long-term behavioral changes through the IGF2-KCC2 pathway
Published 2022-05-01“…Summary: The suprachiasmatic nucleus (SCN) integrates light and systemic signals from peripheral tissues to coordinate physiology and behavior daily rhythms. …”
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246
Dex modulates the balance of water-electrolyte metabolism by depressing the expression of AVP in PVN
Published 2022-08-01“…They are responsible for the secretion of AVP. The suprachiasmatic nucleus (SCN) is also one of the brain regions where AVP neurons are densely distributed in the hypothalamus. …”
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247
Circadian signatures of anterior hypothalamus in time-restricted feeding [version 1; peer review: 2 approved]
Published 2022-09-01“…Background: Meal timing resets circadian clocks in peripheral tissues, such as the liver, in seven days without affecting the phase of the central clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Anterior hypothalamus plays an essential role in energy metabolism, circadian rhythm, and stress response. …”
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248
Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency
Published 2018-11-01“…At the level of the central circadian clock (the suprachiasmatic nucleus, SCN), loss of BLOC-1 caused subtle morphological changes including a larger SCN and increased expression of the relative levels of the clock gene Per2 product during the day but did not affect the neuronal activity rhythms. …”
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249
Differential Expression of Circadian Clock Genes in the Bovine Neuroendocrine Adrenal System
Published 2023-11-01“…Knowledge of circadian rhythm clock gene expression outside the suprachiasmatic nucleus is increasing. The purpose of this study was to determine whether expression of circadian clock genes differed within or among the bovine stress axis tissues (e.g., amygdala, hypothalamus, pituitary, adrenal cortex, and adrenal medulla). …”
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250
Altered Clock Gene Expression in Female APP/PS1 Mice and Aquaporin-Dependent Amyloid Accumulation in the Retina
Published 2023-10-01“…The regulation of circadian rhythm depends on the light information that is projected from the retina to the suprachiasmatic nucleus in the hypothalamus. Studies of AD patients and AD transgenic mice have revealed AD retinal pathology, including amyloid-β (Aβ) accumulation that can directly interfere with the regulation of the circadian cycle. …”
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251
Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action
Published 2022-06-01“…Recruitment of MT receptors in the suprachiasmatic nucleus, thalamic reticular nucleus, and hippocampus appears to fulfil a complimentary role. …”
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252
A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats
Published 2018-04-01“…Consuming a fcHFHS diet for 6 weeks disrupted day–night differences in Per2 mRNA expression in the nucleus accumbens (NAc) and lateral hypothalamus but not in the suprachiasmatic nucleus, habenula, and ventral tegmental area. …”
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253
Timed restricted feeding cycles drive daily rhythms in female rats maintained in constant light but only partially restore the estrous cycle
Published 2022-09-01“…In female rats, constant light (LL) eliminates the estrous cycle leading to a state of persistent estrus. The suprachiasmatic nucleus (SCN) drives circadian rhythms, and it interacts with the neuroendocrine network necessary for reproductive function. …”
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254
Long wavelength light reduces the negative consequences of dim light at night
Published 2023-01-01“…First, we confirmed that the short-wavelength enriched lighting produced strong acute suppression of locomotor activity (masking), robust light-induced phase shifts, and cFos expression in the suprachiasmatic nucleus in wild-type (WT) mice, while the long-wavelength enriched lighting evoked much weaker responses. …”
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255
Sex-dependent circadian alterations of both central and peripheral clock genes expression and gut–microbiota composition during activity-based anorexia in mice
Published 2024-01-01“…Circadian clock genes expression was assessed by RT-qPCR on peripheral (liver, colon and ileum) and central (hypothalamic suprachiasmatic nucleus or SCN) tissues. Cecal bacterial taxa abundances were evaluated by qPCR. …”
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256
Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome
Published 2022-12-01“…Methods: Core and accessory clock gene expression in different gastrointestinal (GI) tissues were determined by qPCR in two different models of circadian disruption - mice with Bmal1 deficiency in the circadian pacemaker, the suprachiasmatic nucleus (Bmal1SCNfl/-), and wild-type mice exposed to simulated shift work (SSW). …”
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257
A non-canonical retina-ipRGCs-SCN-PVT visual pathway for mediating contagious itch behavior
Published 2022-10-01“…Gastrin-releasing peptide (GRP) and its receptor (GRPR) in the suprachiasmatic nucleus (SCN) of the hypothalamus mediates contagious itch behavior in mice. …”
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