Costs and benefits of diagnostic testing: four ways to improve patient care by purposive use of in vitro diagnostics by Carmen Binder, Maximilian Schmid, Thomas Dieterle, Hans Hendrik Schäfer

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Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency by Pauline van Schouwenburg, Pauline van Schouwenburg, Susanne Unger, Susanne Unger, Susanne Unger, Kathryn J. Payne, Kathryn J. Payne, Kathryn J. Payne, Fabian M. P. Kaiser, Fabian M. P. Kaiser, Ingrid Pico-Knijnenburg, Jens Pfeiffer, Oliver Hausmann, David Friedmann, David Friedmann, David Friedmann, Michelle Erbel, Maximilian Seidl, Maximilian Seidl, David van Zessen, Andrew P. Stubbs, Mirjam van der Burg, Klaus Warnatz, Klaus Warnatz

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A bone-based 3D scaffold as an in-vitro model of microenvironment–DLBCL lymphoma cell interaction by Jessica Ceccato, Jessica Ceccato, Maria Piazza, Marco Pizzi, Sabrina Manni, Sabrina Manni, Francesco Piazza, Francesco Piazza, Ilaria Caputo, Francesco Cinetto, Lorena Pisoni, Diletta Trojan, Riccardo Scarpa, Renato Zambello, Renato Zambello, Angelo Paolo Dei Tos, Livio Trentin, Gianpietro Semenzato, Fabrizio Vianello

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Classic Chromophobe Renal Cell Carcinoma Incur a Larger Number of Chromosomal Losses Than Seen in the Eosinophilic Subtype by Riuko Ohashi, Peter Schraml, Silvia Angori, Aashil A. Batavia, Niels J. Rupp, Chisato Ohe, Yoshiro Otsuki, Takashi Kawasaki, Hiroshi Kobayashi, Kazuhiro Kobayashi, Tatsuhiko Miyazaki, Hiroyuki Shibuya, Hiroyuki Usuda, Hajime Umezu, Fumiyoshi Fujishima, Bungo Furusato, Mitsumasa Osakabe, Tamotsu Sugai, Naoto Kuroda, Toyonori Tsuzuki, Yoji Nagashima, Yoichi Ajioka, Holger Moch

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Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study by Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pellegrino Cerino, Claudia Covelli, Mariangela Balestrieri, Gianluca Russo, Antonio Bonfitto, Pasquale Pisapia, Fabiola Fiordelisi, Maria D’Armiento, Dario Bruzzese, Fotios Loupakis, Filippo Pietrantonio, Maria Triassi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano

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Prognostic role of preoperative fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography with an image-based harmonization technique: A multicenter retrospec... by Akira Hamada, MD, PhD, Kazuhiro Kitajima, MD, PhD, Kenichi Suda, MD, PhD, Takamasa Koga, MD, PhD, Junichi Soh, MD, PhD, Hayato Kaida, MD, PhD, Kimiteru Ito, MD, PhD, Tetsuro Sekine, MD, PhD, Kyoshiro Takegahara, MD, PhD, Hiromitsu Daisaki, PhD, Masaki Hashimoto, MD, PhD, Yukihiro Yoshida, MD, PhD, Takanobu Kabasawa, MD, PhD, Takashi Yamasaki, MD, Seiichi Hirota, MD, PhD, Jitsuo Usuda, MD, PhD, Kazunari Ishii, MD, PhD, Tetsuya Mitsudomi, MD, PhD

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How Long Are Reperfusion Therapies Beneficial for Patients after Stroke Onset? Lessons from Lethal Ischemia Following Early Reperfusion in a Mouse Model of Stroke by Takayuki Nakagomi, Yasue Tanaka, Nami Nakagomi, Tomohiro Matsuyama, Shinichi Yoshimura

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Bird‐related non‐fibrotic hypersensitivity pneumonitis with bronchoalveolar lavage fluid eosinophilia that developed after COVID‐19 vaccination: A case report by Takuma Katano, Tomoyuki Ogisu, Akira Satou, Toshiyuki Yonezawa, Hiroyuki Tanaka, Satoru Ito

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Updates and challenges in pancreatic cytopathology by Patrick Yang, Liying Han, Zhongren Zhou

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A case of lymphangioleiomyomatosis with diffuse large B-cell lymphoma: Usefulness of FDG-PET by Mami Orimo, Mitsuko Kondo, Kiyoshi Takeyama, Kenta Masui, Junji Tanaka, Etsuko Tagaya

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Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations by William J. Anderson, Vickie Y. Jo

“…The diagnosis of benign and malignant soft tissue and bone neoplasms is a challenging area of surgical pathology, due to the large number, rarity, and histologic diversity of tumor types. …”
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An unusual testicular mass: myeloid sarcoma as a rare extramedullary manifestation of acute myeloid leukemia by R. Padma Priya Dharshini, S. Babu Peter, G. Chengalvarayan, S. Kalpana

“…The patient underwent unilateral left radical inguinal orchidectomy. Surgical pathology revealed myeloid sarcoma of the testicle. …”
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Application of contrast-enhanced ultrasound in diagnosis and grading of bladder urothelial carcinoma by Hui-ping Zhang, Rong-xi Liang, Xue-ying Lin, En-sheng Xue, Qin Ye, Yi-fan Zhu

“…The ultrasound and surgical pathology results were compared, and their diagnostic efficacy was analyzed. …”
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Oropharyngeal Hairy Polyp: A Case of Respiratory Failure in a Newborn by Paola Feraco, Emma Bragantini, Francesca Incandela, Cesare Gagliardo, Marina Silvestrini

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The last century of symptom-oriented research in emergency presentations – have we made any progress? by Roland Bingisser, Christian Hans Nickel

“…In abdominal pain, progress was achieved over a century ago by correlating symptoms and surgical pathology. Most diagnoses were made by using the clinical tools elaborated with careful observation and clinical examination. …”
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Progression of Well-Differentiated Papillary Mesothelial Tumour to Mesothelioma in a Patient with Ehlers Danlos Syndrome by Sarita Prabhakaran, Matthew Hussey, Kenneth J. O’Byrne, Sonja Klebe

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Development of diffuse large B-cell lymphoma in a patient with Waldenström’s macroglobulinemia/ lymphoplasmacytic lymphoma: clonal identity between two B-cell neoplasms by Masayuki Shiseki, Akihiro Masuda, Norimichi Watanabe, Masami Fujii, Tomofumi Kimura, Kentaro Yoshinaga, Naoki Mori, Masanao Teramura, Toshiko Motoji

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Internal hernia as one of the causes of abdominal pain by V. M. Kitaev, E. G. Koshelev, O. V. Sokolova, G. Yu. Belyaev, A. A. Egorov, O. O. Kurzantseva

“…Internal hernias are a surgical pathology and may be the cause for the development of acute small bowel obstruction and the occurrence of pain. …”
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Meaning of Receiving Artificial Nutritional Support in People in the Postoperative Period of Abdominal Surgery by Nieves Fuentes González, Alejandra Fuentes Ramírez

“…The data analysis shows that the basic surgical pathology and the artificial nutritional support are sudden events that fragment the daily life of the person. …”
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Inference of core needle biopsy whole slide images requiring definitive therapy for prostate cancer by Masayuki Tsuneki, Makoto Abe, Shin Ichihara, Fahdi Kanavati

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