Incidence of the <i>CHEK2</i> Germline Mutation and Its Impact on Clinicopathological Features, Treatment Responses, and Disease Course in Patients with Papillary Thyroid Carcinoma by Danuta Gąsior-Perczak, Artur Kowalik, Krzysztof Gruszczyński, Agnieszka Walczyk, Monika Siołek, Iwona Pałyga, Sławomir Trepka, Estera Mikina, Tomasz Trybek, Janusz Kopczyński, Agnieszka Suligowska, Rafał Ślusarczyk, Agnieszka Gonet, Jarosław Jaskulski, Paweł Orłowski, Magdalena Chrapek, Stanisław Góźdź, Aldona Kowalska

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MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit by Sanne Løkkegaard, Daniel Elias, Carla L. Alves, Martin V. Bennetzen, Anne-Vibeke Lænkholm, Martin Bak, Morten F. Gjerstorff, Lene E. Johansen, Henriette Vever, Christina Bjerre, Tove Kirkegaard, Bo Nordenskjöld, Tommy Fornander, Olle Stål, Linda S. Lindström, Laura J. Esserman, Anne E. Lykkesfeldt, Jens S. Andersen, Rikke Leth-Larsen, Henrik J. Ditzel

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Coexisting Molecular Alterations Increase the Risk of Malignancy in Thyroid Nodules with Copy Number Alterations by Mohannad Rajab, Saruchi Bandargal, Marc Philippe Pusztaszeri, Véronique-Isabelle Forest, Sama Alohali, Sabrina Daniela da Silva, Michael Tamilia, Richard J. Payne

“…Of the 316 patients with thyroid nodules who opted for molecular testing with ThyroSeqV3 followed by surgery, 67 (21.2%) nodules were positive for CNAs, including 23 Bethesda III, 31 Bethesda IV, 12 Bethesda V and 1 Bethesda VI nodules. On surgical pathology, 29.9% were benign and 70.1% were malignant or non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). …”
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Diagnostic accuracy of 99mTc-HYNIC-TOC SPECT/CT for detecting osteomalacia-associated tumors by Bo Li, Lili Duan, Xiali Li, Jingqi Shi, Huiqiang Li, Huimin Liu, Xiaoliang Cheng, Xinyu Wu, Yongju Gao

“…The 99mTc-HYNIC-TOC SPECT/CT findings were compared with the post-surgical pathology diagnosis and clinical follow-up results.ResultsUsing 99mTc-HYNIC-TOC SPECT/CT, suspicious tumors were found in 18 of the 25 patients, and 15 of them underwent surgical resection. …”
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Differential nasal swab cytology represents a valuable tool for therapy monitoring but not prediction of therapy response in chronic rhinosinusitis with nasal polyps treated with D... by Zeynep Danisman, Maximilian Linxweiler, Jan Philipp Kühn, Barbara Linxweiler, Erich-Franz Solomayer, Mathias Wagner, Gudrun Wagenpfeil, Bernhard Schick, Sabrina Berndt

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Evaluation of adalimumab effects on left ventricle performance by echocardiography indexes among patients with immunosuppressant refractory ulcerative colitis by Mohammad Reza Hatamnejad, Mersedeh Karvandi, Fateme Jodatfar, Nastaran Ebrahimi, Fatemeh Shojaeian, Shaghayegh Baradaran Ghavami, Hedieh Balaii, Mahdi Moeeni, Mohsen Rajabnia, Shabnam Shahrokh, Hamid Asadzadeh Aghdaei

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White ring sign is useful for differentiating between fundic gland polyp and gastric adenocarcinoma of fundic gland type by Keitaro Takahashi, Takahiro Sasaki, Nobuhiro Ueno, Haruka Maguchi, Shion Tachibana, Ryunosuke Hayashi, Yu Kobayashi, Yuya Sugiyama, Aki Sakatani, Katsuyoshi Ando, Shin Kashima, Kentaro Moriichi, Hiroki Tanabe, Kazumichi Harada, Sayaka Yuzawa, Shin Ichihara, Toshikatsu Okumura, Mikihiro Fujiya

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CCR7 Mediates Cell Invasion and Migration in Extrahepatic Cholangiocarcinoma by Inducing Epithelial–Mesenchymal Transition by Mitsunobu Oba, Yoshitsugu Nakanishi, Tomoko Mitsuhashi, Katsunori Sasaki, Kanako C. Hatanaka, Masako Sasaki, Ayae Nange, Asami Okumura, Mariko Hayashi, Yusuke Yoshida, Takeo Nitta, Takashi Ueno, Toru Yamada, Masato Ono, Shota Kuwabara, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Kimitaka Tanaka, Kiyoshi Takayama, Yutaka Hatanaka, Satoshi Hirano

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Autoimmune Atrophic Gastritis: The Role of miRNA in Relation to Helicobacter Pylori Infection by Fabiana Zingone, Fabiana Zingone, Valentina Pilotto, Valentina Pilotto, Romilda Cardin, Gemma Maddalo, Gemma Maddalo, Costanza Orlando, Costanza Orlando, Matteo Fassan, Matteo Fassan, Ilaria Marsilio, Eugenio Collesei, Filippo Pelizzaro, Filippo Pelizzaro, Fabio Farinati, Fabio Farinati

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A standardized pathology report for gastric cancer: 2nd edition by Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So-Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho

“…The standard data elements contain the basic pathologic findings and items necessary to predict the prognosis of GC patients, and they are adequate for routine surgical pathology service. Other diagnostic and prognostic factors relevant to adjuvant therapy, including molecular biomarkers, are classified as conditional data elements to allow each pathologist to selectively choose items appropriate to the environment in their institution. …”
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Comprehensive Genomic Profiling (CGP)-Informed Personalized Molecular Residual Disease (MRD) Detection: An Exploratory Analysis from the PREDATOR Study of Metastatic Colorectal Can... by Sara Lonardi, Halla Nimeiri, Chang Xu, Daniel R. Zollinger, Russell W. Madison, Alexander D. Fine, Ole Gjoerup, Cosimo Rasola, Valentina Angerilli, Shruti Sharma, Hsin-Ta Wu, Charuta C. Palsuledesai, Meenakshi Malhotra, Alexey Aleshin, Fotios Loupakis, Elise Renkonen, Priti Hegde, Matteo Fassan

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Induced Pluripotent Stem Cell-Derived Cardiomyocytes with <i>SCN5A</i> R1623Q Mutation Associated with Severe Long QT Syndrome in Fetuses and Neonates Recapitulates Pathophysiologi... by Emiko Hayama, Yoshiyuki Furutani, Nanako Kawaguchi, Akiko Seki, Yoji Nagashima, Keisuke Okita, Daiji Takeuchi, Rumiko Matsuoka, Kei Inai, Nobuhisa Hagiwara, Toshio Nakanishi

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The Presence of Concomitant Mutations Affects the Activity of EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC) Patients by Anna Maria Rachiglio, Francesca Fenizia, Maria Carmela Piccirillo, Domenico Galetta, Lucio Crinò, Bruno Vincenzi, Emiddio Barletta, Carmine Pinto, Francesco Ferraù, Matilde Lambiase, Agnese Montanino, Cristin Roma, Vienna Ludovini, Elisabetta Sara Montagna, Antonella De Luca, Gaetano Rocco, Gerardo Botti, Francesco Perrone, Alessandro Morabito, Nicola Normanno

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Association of Sentinel Node Biopsy and Pathological Report Completeness with Survival Benefit for Cutaneous Melanoma and Factors Influencing Their Different Uses in European Popul... by Milena Sant, Maria Chiara Magri, Andrea Maurichi, Roberto Lillini, Maria José Bento, Eva Ardanaz, Marcela Guevara, Kaire Innos, Rafael Marcos-Gragera, Jordi Rubio-Casadevall, Maria-José Sánchez Pérez, Rosario Tumino, Massimo Rugge, Pamela Minicozzi, the Melanoma HR Study Working Group

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ANALYZING LOCAL AND SYSTEMIC IMMUNE RESPONSES IN PATIENTS WITH ACUTE PHLEGMONOUS PERITONITIS USING A FLOW CYTOFLUOROMETRIC METHOD by Kuyun L. О.

“…The control group consisted of individuals without surgical pathology of the abdominal cavity and other inflammatory diseases (15 people). …”
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CK2β Regulates Hematopoietic Stem Cell Biology and Erythropoiesis by Laura Quotti Tubi, Sara Canovas Nunes, Elisa Mandato, Marco Pizzi, Nicola Vitulo, Mirco D’Agnolo, Raffaella Colombatti, Maddalena Martella, Maria Paola Boaro, Elena Doriguzzi Breatta, Anna Fregnani, Zaira Spinello, Mitja Nabergoj, Odile Filhol, Brigitte Boldyreff, Mattia Albiero, Gian Paolo Fadini, Carmela Gurrieri, Fabrizio Vianello, Gianpietro Semenzato, Sabrina Manni, Livio Trentin, Francesco Piazza

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Poster Colours: Pocket-Friendly Alternative to Tissue Marking Dyes by Mardiana ABDUL AZİZ, Nor Salmah BAKAR, Noor Kaslina MOHD KORNAIN

“…Dear Editor, We read with great interest the paper 'Inking in Surgical Pathology: Does the Method Matter? A Procedural Analysis of a Spectrum of Colours' published in this journal recently and wish to share our small study relating to the same topic1. …”
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Side-specific, Microultrasound-based Nomogram for the Prediction of Extracapsular Extension in Prostate Cancer by Adriana M. Pedraza, Sneha Parekh, Himanshu Joshi, Ralph Grauer, Vinayak Wagaskar, Laura Zuluaga, Raghav Gupta, Flora Barthe, Jordan Nasri, Krunal Pandav, Dhruti Patel, Michael A. Gorin, Mani Menon, Ashutosh K. Tewari

“…Outcome measurements and statistical analysis: ECE on surgical pathology was the primary outcome. Multivariate regression analyses were carried out to identify predictors for ECE. …”
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Pancreatic Cancer is More Frequently Early Stage at Diagnosis in Surgically Resected Intraductal Papillary Mucinous Neoplasms With Preoperative Surveillance by J. de la Fuente, Jacob Lui, Ryan J. Lennon, Arjun Chatterjee, Rondell P. Graham, Lizhi Zhang, Michael L. Kendrick, Mark J. Truty, Sean P. Cleary, Rory L. Smoot, David M. Nagorney, Ferga C. Gleeson, Michael J. Levy, Vinay Chandrasekhara, Randall K. Pearson, Bret T. Petersen, Santhi S. Vege, Suresh T. Chari, Shounak Majumder

“…Conclusion: Surveillance-detected pancreatic cancers in patients with IPMNs are more frequently stage I, and IPMN-HGD on surgical pathology is associated with significant risk of future pancreatic cancer. …”
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Malignant testicular unclassified sex cord stromal tumor: a case report by Shingo Morinaga, Shigeyuki Aoki, Toyonori Tsuzuki, Keiko Kanematsu, Naoki Kawai, Sayuri Sato, Kotomi Nakamizu, Kana Goto, Miho Niwa, Ikuko Nomura, Tomoko Sawada, Ruriko Futamachi, Fujio Morita, Yoshiaki Yamada

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