Molecular mechanisms of synaptogenesis / by Dityatev, Alexander, El-Husseini, Alaa

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Nerve, Muscle, and Synaptogenesis by Lauren Eric Swenarchuk

“…Moreover, the current model also proposes that agrin can serve two functions, to induce synaptogenesis and to stabilize new synapses, once these are formed. …”
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Molecular mechanisms of synaptogenesis by Cai Qi, Li-Da Luo, Li-Da Luo, Irena Feng, Shaojie Ma

“…Additionally, genes involved in synaptogenesis are also frequently associated with neurological or psychiatric disorders, suggesting a relationship between synaptogenesis and brain physiology and pathology. …”
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Neuromodulation of excitatory synaptogenesis in striatal development by Yevgenia Kozorovitskiy, Rui Peixoto, Wengang Wang, Arpiar Saunders, Bernardo L Sabatini

“…We evaluated the in vivo effects of enhanced glutamate release from corticostriatal axons and postsynaptic PKA and discovered a mechanism of developmental plasticity wherein rapid synaptogenesis is promoted by the coordinated actions of glutamate and postsynaptic Gαs-coupled receptors.…”
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Origin, Development, and Synaptogenesis of Cortical Interneurons by Alfredo Llorca, Ruben Deogracias, Ruben Deogracias, Ruben Deogracias

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Wnt signaling in synaptogenesis of Alzheimer's disease by Cheng‐Ting Zhang, Joy Wang, Wen‐Yuan Wang

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Activity-dependent synaptogenesis in developing rat hippocampus by Lauri, SE, Lamsa, K, Pavlov, I, Rickki, R, Rauvala, H, Taira, T

Astrocytic Factors Controlling Synaptogenesis: A Team Play by Giuliana Fossati, Michela Matteoli, Elisabetta Menna

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Adaptive Synaptogenesis Constructs Neural Codes That Benefit Discrimination. by Blake T Thomas, Davis W Blalock, William B Levy

“…Specifically, the adaptive algorithm includes synaptogenesis, synaptic shedding, and bi-directional synaptic weight modification to produce a network with outputs (i.e. neural codes) that represent input patterns proportional to the frequency of related patterns. …”
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Circadian regulation of developmental synaptogenesis via the hypocretinergic system by Xu-Fei Du, Fu-Ning Li, Xiao-Lan Peng, Bing Xu, Yu Zhang, Guang Li, Taole Liu, Ying Li, Han Wang, Jun Yan, Jiu-Lin Du

“…Thus, our findings demonstrate that the developmental synaptogenesis is under hypocretin-dependent circadian regulation, suggesting an important role of the circadian clock in neural development.…”
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Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses by Wurtman, Richard Jay

“…The loss of hippocampal and cortical synapses, resulting from impaired synaptogenesis, accelerated synaptic degeneration, or both, is one of the earliest neuropathologic findings in Alzheimer’s Disease and is the finding that best correlates with cognitive symptoms (DeKosky and Scheff, 1990; Terry et al., 1991; Selkoe, 2002). …”
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Adaptive Synaptogenesis Constructs Neural Codes That Benefit Discrimination by Thomas, Blake T., Levy, William B., Blalock, Davis

“…Specifically, the adaptive algorithm includes synaptogenesis, synaptic shedding, and bi-directional synaptic weight modification to produce a network with outputs (i.e. neural codes) that represent input patterns proportional to the frequency of related patterns. …”
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Sequences of synaptogenesis in the human fetal and neonatal brain by synaptophysin immunocytochemistry by Harvey B. Sarnat

Subjects: “…synaptogenesis…”
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Type IIa RPTPs and Glycans: Roles in Axon Regeneration and Synaptogenesis by Kazuma Sakamoto, Tomoya Ozaki, Yuji Suzuki, Kenji Kadomatsu

“…We highlight here the significance of these interactions in axon regeneration and synaptogenesis. For example, PTPσ, a member of type IIa RPTPs, on axon terminals is monomerized and activated by the extracellular CS deposited in neural injuries, dephosphorylates cortactin, disrupts autophagy flux, and consequently inhibits axon regeneration. …”
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The RNA-binding protein NANOS1 controls hippocampal synaptogenesis. by Darío Maschi, Ana J Fernández-Alvarez, Graciela Lidia Boccaccio

“…These results expand our knowledge on the role of NANOS1 in CNS development and suggest that RNA regulation by NANOS1 governs hippocampal synaptogenesis.…”
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Structural plasticity of dendritic secretory compartments during LTP-induced synaptogenesis by Yelena D Kulik, Deborah J Watson, Guan Cao, Masaaki Kuwajima, Kristen M Harris

“…These findings suggest local secretory trafficking contributes to LTP-induced synaptogenesis and primes the new spines for future plasticity.…”
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Non-canonical interplay between glutamatergic NMDA and dopamine receptors shapes synaptogenesis by Nathan Bénac, G. Ezequiel Saraceno, Corey Butler, Nahoko Kuga, Yuya Nishimura, Taiki Yokoi, Ping Su, Takuya Sasaki, Mar Petit-Pedrol, Rémi Galland, Vincent Studer, Fang Liu, Yuji Ikegaya, Jean-Baptiste Sibarita, Laurent Groc

“…It was higher early in development, promoting the formation of NMDAR-D1R complexes in an mGluR5- and CK1-dependent manner, favoring NMDAR clusters and synaptogenesis in a dopamine receptor signaling-independent manner. …”
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Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control by Francesco Paolo Ulloa Severino, Oluwadamilola O. Lawal, Kristina Sakers, Shiyi Wang, Namsoo Kim, Alexander David Friedman, Sarah Anne Johnson, Chaichontat Sriworarat, Ryan H. Hughes, Scott H. Soderling, Il Hwan Kim, Henry H. Yin, Cagla Eroglu

“…Training-induced synaptogenesis is controlled by the Gabapentin/Thrombospondin receptor α2δ−1, which is an essential neuronal protein for proper intracortical excitatory synaptogenesis. …”
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Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis by Coles, C, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A, Nakagawa, T, Craig, A, Jones, E, Aricescu, A

“…Receptor protein tyrosine phosphatase sigma (RPTPσ) regulates neuronal extension and acts as a presynaptic nexus for multiple protein and proteoglycan interactions during synaptogenesis. Unknown mechanisms govern the shift in RPTPσ function, from outgrowth promotion to synaptic organization. …”

Crocin Administration from Childhood to Adulthood Increases Hippocampal Neurogenesis and Synaptogenesis in Male Mice by Babak Ebrahimi, Shayan Vafaei, Seyed Hamid Reza Rastegar-Moghaddam, Mahmoud Hosseini, Fatemeh Tajik Yabr, Abbas Mohammadipour

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