β‐RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9R239X mice by Agustín Hidalgo‐Gutiérrez, Eliana Barriocanal‐Casado, Mohammed Bakkali, M Elena Díaz‐Casado, Laura Sánchez‐Maldonado, Miguel Romero, Ramy K Sayed, Cornelia Prehn, Germaine Escames, Juan Duarte, Darío Acuña‐Castroviejo, Luis C López

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The Endoplasmic Reticulum-Mitochondria Encounter Structure Complex Coordinates Coenzyme Q Biosynthesis by Michal Eisenberg-Bord, Hui S. Tsui, Diana Antunes, Lucía Fernández-del-Río, Michelle C. Bradley, Cory D. Dunn, Theresa P. T. Nguyen, Doron Rapaport, Catherine F. Clarke, Maya Schuldiner

“…Fluorescence microscopy experiments demonstrate close proximity between the CoQ synthome and ERMES, suggesting a spatial coordination. …”
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Predicting and Understanding the Pathology of Single Nucleotide Variants in Human <i>COQ</i> Genes by Sining Wang, Akash Jain, Noelle Alexa Novales, Audrey N. Nashner, Fiona Tran, Catherine F. Clarke

“…Here we analyzed the structural and functional impact of 429 human missense single nucleotide variants (SNVs) that give rise to amino acid substitutions in the conserved and functional regions of human genes encoding a high molecular weight complex known as the CoQ synthome (or Complex Q), consisting of the <i>COQ3</i>–<i>COQ7</i> and <i>COQ9</i> gene products. …”
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Bed for three by C. Vallecillo Adame, T. Jiménez Aparicio, C. De Andrés Lobo, M. Queipo De Llano De La Viuda, G. Guerra Valera, A. Gonzaga Ramírez, I. Santos Carrasco, J. Gonçalves Cerejeira, C. Capella Meseguer, E. Rodríguez Vázquez

“…Family claims good conygal relation until these synthoms began and no signs of cognitive impairment. …”
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