Moving towards system genetics through multiple trait analysis in genome-wide association studies by Daniel eShriner

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Genetic variation of putative myokine signaling is dominated by biological sex and sex hormones by Leandro M Velez, Cassandra Van, Timothy Moore, Zhenqi Zhou, Casey Johnson, Andrea L Hevener, Marcus M Seldin

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Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function by Jeffrey Molendijk, Ronnie Blazev, Richard J Mills, Yaan-Kit Ng, Kevin I Watt, Daryn Chau, Paul Gregorevic, Peter J Crouch, James BW Hilton, Leszek Lisowski, Peixiang Zhang, Karen Reue, Aldons J Lusis, James E Hudson, David E James, Marcus M Seldin, Benjamin L Parker

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Integrated systems analysis reveals conserved gene networks underlying response to spinal cord injury by Jordan W Squair, Seth Tigchelaar, Kyung-Mee Moon, Jie Liu, Wolfram Tetzlaff, Brian K Kwon, Andrei V Krassioukov, Christopher R West, Leonard J Foster, Michael A Skinnider

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Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse by Pratyaydipta Rudra, Wen J. Shi, Pamela Russell, Brian Vestal, Boris Tabakoff, Paula Hoffman, Katerina Kechris, Laura Saba

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Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach by Yang Cao, Ruben Aquino-Martinez, Evan Hutchison, Hooman Allayee, Aldons J. Lusis, Federico E. Rey

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Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans by Liang-Yu Lin, Sunny Chun Chang, Jim O’Hearn, Simon T. Hui, Marcus Seldin, Pritha Gupta, Galyna Bondar, Mario Deng, Raimo Jauhiainen, Johanna Kuusisto, Markku Laakso, Janet S. Sinsheimer, Arjun Deb, Christoph Rau, Shuxun Ren, Yibin Wang, Aldons J. Lusis, Jessica J. Wang, Adriana Huertas-Vazquez

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Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues by Mingqi Zhou, Ian Tamburini, Cassandra Van, Jeffrey Molendijk, Christy M Nguyen, Ivan Yao-Yi Chang, Casey Johnson, Leandro M Velez, Youngseo Cheon, Reichelle Yeo, Hosung Bae, Johnny Le, Natalie Larson, Ron Pulido, Carlos HV Nascimento-Filho, Cholsoon Jang, Ivan Marazzi, Jamie Justice, Nicholas Pannunzio, Andrea L Hevener, Lauren Sparks, Erin E Kershaw, Dequina Nicholas, Benjamin L Parker, Selma Masri, Marcus M Seldin

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Joint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases by Michael J. McGeachie, George L. Clemmer, Jessica Lasky-Su, Amber Dahlin, Benjamin A. Raby, Scott T. Weiss

Subjects: “…Systems genetics…”
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Systems genetics approaches for understanding complex traits with relevance for human disease by Hooman Allayee, Charles R Farber, Marcus M Seldin, Evan Graehl Williams, David E James, Aldons J Lusis

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Role of Matrix Gla Protein in Transforming Growth Factor-β Signaling and Nonalcoholic Steatohepatitis in MiceSummary by Simon T. Hui, Lili Gong, Chantle Swichkow, Montgomery Blencowe, Dorota Kaminska, Graciel Diamante, Calvin Pan, Meet Dalsania, Samuel W. French, Clara E. Magyar, Päivi Pajukanta, Jussi Pihlajamäki, Kristina I. Boström, Xia Yang, Aldons J. Lusis

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Epigenetic analysis in a murine genetic model of Gulf War illness by Khyobeni Mozhui, Khyobeni Mozhui, James P. O’Callaghan, David G. Ashbrook, Pjotr Prins, Wenyuan Zhao, Lu Lu, Byron C. Jones, Byron C. Jones

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From integrative genomics to systems genetics in the rat to link genotypes to phenotypes by Aida Moreno-Moral, Enrico Petretto

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Recombinant inbred systems can advance research in behavioural ecology by Beatrice eGini, Reinmar eHager

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Weighted gene co-expression network analysis identifies key hub genes and pathways in acute myeloid leukemia by Xinfeng Wang, Akhilesh K. Bajpai, Qingqing Gu, Qingqing Gu, David G. Ashbrook, Athena Starlard-Davenport, Lu Lu

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Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk by Sean Bankier, Sean Bankier, Sean Bankier, Lingfei Wang, Andrew Crawford, Andrew Crawford, Ruth A. Morgan, Ruth A. Morgan, Arno Ruusalepp, Arno Ruusalepp, Arno Ruusalepp, Ruth Andrew, Johan L. M. Björkegren, Johan L. M. Björkegren, Johan L. M. Björkegren, Brian R. Walker, Brian R. Walker, Tom Michoel, Tom Michoel

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Cardiac copper content and its relationship with heart physiology: Insights based on quantitative genetic and functional analyses using BXD family mice by Akhilesh Kumar Bajpai, Qingqing Gu, Qingqing Gu, Buyan-Ochir Orgil, Buyan-Ochir Orgil, Fuyi Xu, Fuyi Xu, Carolina Torres-Rojas, Wenyuan Zhao, Chen Chen, Athena Starlard-Davenport, Byron Jones, Djamel Lebeche, Jeffrey A. Towbin, Jeffrey A. Towbin, Jeffrey A. Towbin, Enkhsaikhan Purevjav, Enkhsaikhan Purevjav, Lu Lu, Wenjing Zhang

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The impact of genomic variation on protein phosphorylation states and regulatory networks by Jan Grossbach, Ludovic Gillet, Mathieu Clément‐Ziza, Corinna L Schmalohr, Olga T Schubert, Maximilian Schütter, Julia S P Mawer, Christopher A Barnes, Isabell Bludau, Matthias Weith, Peter Tessarz, Martin Graef, Ruedi Aebersold, Andreas Beyer

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When diet meets genetics by Karthickeyan Chella Krishnan

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Collaborative mining of public data resources in neuroinformatics by Rupert W Overall, Robert W Williams, J Alexander Heimel

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