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DNA damage responses to loss of telomere integrity
Published 2013“…Interestingly, several DNA damage factors are required for proper telomere maintenance, drawing a thin line between telomere protection and their recognition as broken DNA ends.…”
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Telomere maintenance: all's well that ends well.
Published 2009“…Of particular interest in this respect are the ways in which telomere-binding proteins and components of the DNA damage response machinery may facilitate replication fork progression through telomeres.…”
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How homologous recombination maintains telomere integrity
Published 2015“…Here, we discuss the mechanisms by which HR modulates the response to intrinsic cellular challenges that arise during telomere replication, as well as its impact on the assembly of telomere protective structures. …”
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Investigating a role for telomeric transcription in cancer
Published 2018“…<p>A constitutive hallmark of cancers is the extension of telomeric DNA. Approximately 85% of cancers extend their telomeres through the upregulation of the enzyme telomerase; whereas the remaining proportion use a recombination-based method known as Alternative Lengthening of Telomeres pathway (ALT). …”
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Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA)
Published 2019-02-01Subjects: Get full text
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Telomere formation on macronuclear chromosomes of <it>Oxytricha trifallax</it> and <it>O. fallax</it>: alternatively processed regions have multiple telomere addition sites
Published 2002-08-01“…<p>Abstract</p> <p>Background</p> <p>Ciliates employ massive chromatid breakage and <it>de novo</it> telomere formation during generation of the somatic macronucleus. …”
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292
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Relative Leukocyte Telomere Length and Genetic Variants in Telomere-Related Genes and Serum Levels Role in Age-Related Macular Degeneration
Published 2022-11-01Subjects: “…relative leukocyte telomere length…”
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294
Telomere sequence variability in genotypes from natural plant populations: unusual block-organized double-monomer terminal telomeric arrays
Published 2023-09-01Subjects: Get full text
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295
Screening for subtelomeric chromosome abnormalities in children with idiopathic mental retardation using multiprobe telomeric FISH and the new MAPH telomeric assay.
Published 2001“…Seventy patients with idiopathic mental retardation have been screened using the established multiprobe telomeric FISH assay and the new MAPH telomeric assay, for all telomeres. …”
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A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content
Published 2023-09-01“…Abstract Tumor cells need to activate a telomere maintenance mechanism, enabling limitless replication. …”
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299
A telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max
Published 2024-02-01Subjects: Get full text
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300
Body mass index and shortened telomere length in middle-aged female and male RUNNING HEAD: Middle-aged and shortened telomere length
Published 2022-04-01Subjects: “…Gender, obesity, physio-biochemical analyses, telomere…”
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