Showing 1 - 20 results of 2,787 for search '"telomeres"', query time: 0.10s Refine Results
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    The Role of Telomere in Cell; Telomere Dysfunction and Tumorigenesis by Majid Kheirollahi, Mahsa Kolahdouz, Fatemeh Ahangari, Leila Koulivand, Fariborz Khorvash

    Published 2013-03-01
    “…Telomeres protect the ends of chromosomes, but can also inhibit the expression of nearby genes, called telomere position effect. …”
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    Article
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    Multiple genome alignment in the telomere-to-telomere assembly era by Bryce Kille, Advait Balaji, Fritz J. Sedlazeck, Michael Nute, Todd J. Treangen

    Published 2022-08-01
    “…Abstract With the arrival of telomere-to-telomere (T2T) assemblies of the human genome comes the computational challenge of efficiently and accurately constructing multiple genome alignments at an unprecedented scale. …”
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    Telomeres and Cancer by Hueng-Chuen Fan, Fung-Wei Chang, Jeng-Dau Tsai, Kao-Min Lin, Chuan-Mu Chen, Shinn-Zong Lin, Ching-Ann Liu, Horng-Jyh Harn

    Published 2021-12-01
    “…Telomeres cap the ends of eukaryotic chromosomes and are indispensable chromatin structures for genome protection and replication. …”
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    Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation. by Tarsounas, M, West, S

    Published 2005
    “…HR also plays a role in the maintenance of eukaryotic telomeres; cells defective in the recombinational repair proteins RAD51D or RAD54 exhibit telomere shortening and end-to-end chromosome fusions. …”
    Journal article
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    Telomere-to-telomere genome sequence of the model mould pathogen Aspergillus fumigatus by Paul Bowyer, Andrew Currin, Daniela Delneri, Marcin G. Fraczek

    Published 2022-09-01
    “…Here, Bowyer et al. use long-read and short-read sequencing to generate complete chromosome assemblies and telomere-to-telomere coverage for two isolates, thus providing high-quality reference genomes as fundamental resources to study this pathogen.…”
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    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres by Robert Lu, Christopher B. Nelson, Samuel Rogers, Anthony J. Cesare, Alexander P. Sobinoff, Hilda A. Pickett

    Published 2024-01-01
    “…Summary: Alternative lengthening of telomeres (ALT) is a homology-directed repair mechanism that becomes activated in a subset of cancers to maintain telomere length. …”
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    An optimized set of human telomere clones for studying telomere integrity and architecture by Knight, S, Lese, C, Precht, K, Kuc, J, Ning, Y, Lucas, S, Regan, R, Brenan, M, Nicod, A, Lawrie, N, Cardy, D, Nguyen, H, Hudson, T, Riethman, H, Ledbetter, D, Flint, J

    Published 2000
    “…Telomere-specific clones are a valuable resource for the characterization of chromosomal rearrangements. …”
    Journal article
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    An optimized set of human telomere clones for studying telomere integrity and architecture. by Knight, S, Lese, C, Precht, K, Kuc, J, Ning, Y, Lucas, S, Regan, R, Brenan, M, Nicod, A, Lawrie, N, Cardy, D, Nguyen, H, Hudson, T, Riethman, H, Ledbetter, D, Flint, J

    Published 2000
    “…Telomere-specific clones are a valuable resource for the characterization of chromosomal rearrangements. …”
    Journal article