Self-managing symptoms of Long COVID: an education and strategies research protocol by Julia Rybkina, Nithin Jacob, Brenda Colella, David Gold, Donna E. Stewart, Lesley A. Ruttan, Liesel-Ann C. Meusel, Mary P. McAndrews, Susan Abbey, Robin Green, Robin Green

“…In response to this gap, we have developed a virtual education intervention synthesized by psychiatrists and clinical psychologists for the current study. We will undertake a two-phase randomized controlled trial to determine the feasibility (Phase 1; N = 90) and efficacy (Phase 2; sample sized based on phase 1 results) of the novel 8 week Education and Self-Management Strategies group compared to a mindfulness skills program, both delivered virtually. …”
Get full text

Population modelling and genetics of a critically endangered Madagascan palm Tahina spectabilis by Alison Shapcott, Heather James, Laura Simmons, Yoko Shimizu, Lauren Gardiner, David Rabehevitra, Rokiman Letsara, Stuart Cable, John Dransfield, William J. Baker, Mijoro Rakotoarinivo

“…We developed population matrix models based on observed demographic data to model population change and predict the species vulnerability to extinction by undertaking population viability analysis (PVA). We investigated the potential conservation value of reintroduced planted populations within the species potential suitable habitat. …”
Get full text

Studies in Cancer Epigenetics through a Sex and Gendered Lens: A Comprehensive Scoping Review by Katherine Huerne, Sarah S. Jackson, Rina Lall, Nicole Palmour, Alison May Berner, Charles Dupras, Yann Joly

“…However, little has been done to assess the state of sex and gender-based analyses (SGBA) in this field. The aim was to undertake a critical evaluation of sex and gender representation, discussion, and data analysis within the cancer epigenetics field since 2010. …”
Get full text

The evidence for interventions in early childhood allergy prevention – towards a living systematic review: protocol [version 2; peer review: 1 approved, 2 approved with reservation... by Christian Apfelbacher, Michael Perkin, Jon Genuneit, Helge Knüttel, Jiancong Wang, Christina Tischer, Uwe Matterne

“…Using this methodology, we aim to undertake constant evidence surveillance, three-monthly search updates, and review updates every three months, should new evidence emerge. …”
Get full text

A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations] by Christine Orengo, Sameer Velankar, Shoshana Wodak, Vincent Zoete, Alexandre M.J.J. Bonvin, Arne Elofsson, K. Anton Feenstra, Dietland L. Gerloff, Thomas Hamelryck, John M. Hancock, Manuela Helmer-Citterich, Adam Hospital, Modesto Orozco, Anastassis Perrakis, Matthias Rarey, Claudio Soares, Joel L. Sussman, Janet M. Thornton, Pierre Tuffery, Gabor Tusnady, Rikkert Wierenga, Tiina Salminen, Bohdan Schneider

“…Our Community will also undertake dedicated educational, training and outreach efforts to facilitate this, bringing new insights and thus facilitating the development of much needed innovative applications e.g. for human health, drug and protein design. …”
Get full text

Hidden hunger in patients with type 2 diabetes (T2D) and its effect on glycaemic control: a protocol for systematic review and meta-analysis by Shiv Dutt Gupta, Daya Krishan Mangal, Diksha Gautam, Anuj Kumar Pandey, Nida Shaikh, Sidharth Sekhar Mishra, Himanshu Tolani, Yeshwanth Sonnathi, Kamlesh Chand Sharma, Jagdish Prasad, Rajeev Tewari, Fahmina Anwar

“…It includes all eligible studies reporting the prevalence of micronutrient deficiencies and their effect on glycaemic control in T2D patients. We would undertake a comprehensive literature search across databases: PubMed, Scopus, EMBASE, LILACS, ProQuest, Google Scholar and grey literature, and identify the studies meeting the inclusion criteria. …”
Get full text

Balancing Reproductive and Productive Responsibilities: Childcare Strategies Implemented by Migrant Mothers in the Thailand–Myanmar Border Region by Lisa Wight, Nway Nway Oo, Naw Pue Pue Mhote, Supaporn Trongsakul, Eva Purkey, Susan A. Bartels, Heather M. Aldersey, Colleen M. Davison

“…Results: The results highlight how migrant mothers undertake significant reproductive responsibilities, such as breastfeeding and child-rearing, as well as productive responsibilities, including paid labour in the agricultural, formal, and informal sectors. …”
Get full text

Examining the quality and population representativeness of linked survey and administrative data: guidance and illustration using linked 1958 National Child Development Study and H... by Richard Silverwood, Nasir Rajah, Lisa Calderwood, Bianca De Stavola, Katie Harron, George Ploubidis

“…Conclusions Through this work we hope to encourage providers and users of linked data resources to undertake and publish thorough evaluations. We further hope that providing illustrative analyses using linked NCDS-HES data will improve the quality and transparency of research using this particular linked data resource. …”
Get full text

Antiplatelet Therapy Improves the Prognosis of Patients with Hepatocellular Carcinoma by Tsuguru Hayashi, Michihiko Shibata, Shinji Oe, Koichiro Miyagawa, Yuichi Honma, Masaru Harada

“…Results: The numbers of patients who did and did not undertake antiplatelet therapy were 111 and 661, respectively. …”
Get full text

Emerging chemical engineering of exosomes as “bioscaffolds” in diagnostics and therapeutics by Jianwei Wang, Meijiao Wang, Ning Jiang, Shijia Ding, Qiling Peng, Lei Zheng

“…After revisiting EXO-mediated diagnosis/treatment, the most popular strategies to directly undertake loadings of exogenous cargos on EXOs include genetic and chemical engineering. …”
Get full text

The association between academic stress, social support, and self-regulatory fatigue among nursing students: a cross-sectional study based on a structural equation modelling approa... by Zhang Yuhuan, Zheng Pengyue, Chen Dong, Niu Qichao, Pang Dong, Song Anqi, Jiang Hongbo, Di Zhixin

“…For statistical analysis, the independent t-test, Kruskal Wallis test, and Pearson correlation coefficient were used. In addition, we undertake analyses using structural equation modeling. …”
Get full text

An analysis of 5G-MIMO communication system based SS for centralized cooperative and non-cooperative users by Waleed Algriree, Nasri Sulaiman, Maryam M. Isa, Ratna K.Z. Sahbudin, Siti L.M. Hassan, Emad Hmood Salman

“…Also, to be considered is the spectrum’s waveform, which is the type that contends with 5G networks specifically. This undertaking involves the development of a 5G-MIMO communication system based SS, in which the spectrum is enhanced, by way of a spectrum sensing (SS) algorithm. …”
Get full text

Effects of feed transition on digestive tract digestive enzyme, morphology and intestinal community in cuttlefish (Sepia pharaonis) by Maowang Jiang, Wencheng Xiao, Jingtao Ye, Liting Xu, Ruibing Peng, Qingxi Han, Zhenming Lü, Huilai Shi, Xiamin Jiang

“…In this study, we investigate the digestive enzyme of S. pharaonis and undertake histological observations of the digestive gland and intestine. …”
Get full text

The value of community science data to analyze long-term avian trends in understudied regions: The state of birds in Türkiye by Kyle D. Kittelberger, Colby J. Tanner, Nikolas D. Orton, Çağan Hakkı Şekercioğlu

“…In this study, we used eBird data submitted by observers in Türkiye to undertake the first long-term assessment of the state of the country's birds from 2001 to 2022. …”
Get full text

A Study on the Outcome of Targeted Temperature Management Comparing Cardiac Arrest Patients Who Received Bystander Cardiopulmonary Resuscitation With Those Who Did Not, Using the N... by Fang-Yu Liou, Fang-Yu Liou, Min-Shan Tsai, Li-Kuo Kuo, Li-Kuo Kuo, Hsin-Hui Hsu, Chih-Hung Lai, Chih-Hung Lai, Kun-Chang Lin, Wei-Chun Huang, Wei-Chun Huang, Wei-Chun Huang

“…It had a higher average GCS score (11.3 vs. 8.31, P < 0.0001) and a lower average Glasgow–Pittsburgh cerebral performance category (CPC) scale score (2.14 vs. 2.98, P < 0.0001). After undertaking a multiple logistic regression analysis, it was found that BCPR was a significant positive predictor for in-hospital survival (OR = 0.66, 95% CI: 0.45–0.97, P = 0.0363).ConclusionsThis study demonstrated that BCPR had a positive survival and neurological impact on the return of spontaneous circulation (ROSC) in patients receiving TTM after cardiac arrest.…”
Get full text

Adopting a Citizen Science Approach in Translational Experimental Medicine Research in Non-Alcoholic Fatty Liver Disease: A Study Protocol by Syed Ghulam Sarwar Shah, Yolanda Barrado-Martín, Thomas Marjot, Jeremy W. Tomlinson, Vasiliki Kiparoglou

“…Citizen scientists will be trained in the research tasks they will undertake, and will be either co-authors or their names will be mentioned in the acknowledgements in research paper(s) based on the level of research contributions. …”
Get full text

Accounting for complexity – Intervention design in the context of studying social accountability for reproductive health [version 2; peer review: 1 approved, 2 approved with reserv... by James Kiarie, Petrus S. Steyn, Alice Monyo, Patrick Kinemo, Jacob Tetteh Ahuno, Mary Awelana Addah, Joanna Paula Cordero, Osei-Bonsu Gyamfi, Victoria Boydell, Heather McMullen

“…We also measure outcomes related to current social accountability theories of change and undertake a process evaluation. We present three design components: aspects of co-design, ‘conceptual’ fidelity, and how we aim to track the intervention as ‘intended vs. implemented’ to explore how the intervention could be responsive to the embedded routines, local contextual realities, and the processual nature of the social accountability intervention. …”
Get full text

<i>Z</i>-Guggulsterone Is a Potential Lead Molecule of Dawa-ul-Kurkum against Hepatocellular Carcinoma by Meenakshi Gupta, Shaikh Maryam Ghufran, Tasneem Kausar, Rafat Ali, Subhrajit Biswas, Shahid M. Nayeem, Romana Ishrat, Sher Ali, Ajaz Ahmad, Irfan A. Rather, Maryam Sarwat

“…Further validation of the binding efficiency of <i>Z</i>-guggulsterone was undertaking using molecular dynamics (MD) simulation studies. …”
Get full text

The Role of Toll-like Receptor 2 (TLR2) in the Development and Progression of Hashimoto’s Disease (HD): A Case Study on Female Patients in Poland by Maria Klatka, Agnieszka Polak, Paulina Mertowska, Sebastian Mertowski, Jakub Łyczba, Anna Hymos, Izabela Korona-Głowniak, Ewelina Grywalska

“…Due to the diverse factors affecting the etiopathogenesis of this disease (hormonal disorders and genetic and environmental factors), as well as the direct involvement of the immune system, scientists are increasingly willing to undertake research aimed at explaining the impact of the loss of immune tolerance and reactivity of autoantigens on the development of the disease. …”
Get full text

Age- and sex-stratified detection rates and associated factors of colorectal neoplasia in the Tianjin colorectal cancer screening program from 2012 to 2020 by Zhen Yuan, Shuyuan Wang, Yuqi Wang, Hongzhou Li, Weifeng Gao, Xinyu Liu, Youkui Han, Zhaoce Liu, Qinghuai Zhang, Hong Ma, Junying Wang, Xiaomeng Wei, Xipeng Zhang, Wei Cui, Chunze Zhang

“…For 57,971 participants undertaking colonoscopy, the detection rates of nonadvanced adenoma, advanced adenoma and CRC were 37.8%, 5.7% and 1.6%, respectively. …”
Get full text