Effectiveness of virtual reality on functional mobility during treadmill training in children with cerebral palsy: a single-blind, two-arm parallel group randomised clinical trial... by Mirari Ochandorena-Acha, Marc Terradas-Monllor, Tania Fabiola Nunes Cabrera, Meritxell Torrabias Rodas, Sergi Grau

“…The participants will be randomly allocated into two groups: (1) the experimental group, which will receive the treadmill training at the same time as the virtual reality; and (2) the control group, which will undertake treadmill gait training alone. The training will be provided in 10 sessions over 2 weeks with 30 min for each session. …”
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Parental spiritual and religious beliefs and behaviour data collected from the Avon Longitudinal Study of Parents and Children, 2020 [version 3; peer review: 1 approved, 2 approved... by Kate Northstone, Jean Golding, Yasmin Iles-Caven, Iain Bickerstaffe, Steven Gregory

“…For partners, the corresponding figures are: ‘yes’ 37.0% vs. 30.0%; ‘no’ 28.6% vs. 45.3% and ‘not sure’ 34.5% vs. 24.6%. We plan to undertake detailed analyses of the antecedents and consequences of RBSS. …”
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Wildfire Susceptibility Mapping Using Deep Learning Algorithms in Two Satellite Imagery Dataset by Nazanin Bahadori, Seyed Vahid Razavi-Termeh, Abolghasem Sadeghi-Niaraki, Khalifa M. Al-Kindi, Tamer Abuhmed, Behrokh Nazeri, Soo-Mi Choi

“…To effectively manage disasters and bolster community resilience, the development of wildfire susceptibility maps (WFSMs) has emerged as a crucial undertaking in recent years. In this research endeavor, two deep learning algorithms were leveraged to generate WFSMs using two distinct remote sensing datasets. …”
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Prevalence and pattern of multimorbidity among chronic kidney disease patients: a community study in chronic kidney disease hotspot area of Eastern India by Subrata Kumar Palo, Soumya Ranjan Nayak, Debadutta Sahoo, Swetalina Nayak, Ashis Kumar Mohapatra, Aviram Sahoo, Pujarini Dash, Sanghamitra Pati

“…Regular screening of CKD patient for other chronic conditions (hypertension, diabetes, peptic ulcer disease, osteoarthritis and heart diseases) would help in detecting them early and undertake prompt management. The existing national program could be leveraged to achieve this.…”
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Comparison of CD3e Antibody and CD3e-sZAP Immunotoxin Treatment in Mice Identifies sZAP as the Main Driver of Vascular Leakage by Shihyoung Kim, Rajni Kant Shukla, Eunsoo Kim, Sophie G. Cressman, Hannah Yu, Alice Baek, Hyewon Choi, Alan Kim, Amit Sharma, Zhirui Wang, Christene A. Huang, John C. Reneau, Prosper N. Boyaka, Namal P. M. Liyanage, Sanggu Kim

“…Despite significant advances in mAb and IT engineering, vascular leakage syndrome (VLS) remains a major dose-limiting toxicity for ITs and has been poorly characterized for recent “engineered” mAbs. This study undertakes a direct comparison of non-mitogenic CD3e-mAb (145-2C11 with Fc-silent^TM murine IgG1: S-CD3e-mAb) and a new murine-version CD3e-IT (saporin–streptavidin (sZAP) conjugated with S-CD3e-mAb: S-CD3e-IT) and identifies their distinct toxicity profiles in mice. …”
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Macro-Morphological and Ecological Variation in <i>Rosa sericea</i> Complex by Fazal Ullah, Yundong Gao, İdris Sari, Rui-Fang Jiao, Saddam Saqib, Xin-Fen Gao

“…So far, the significant inferences meant for the niche occupy the most incredible comparative research, taking the impermanent nature of taxa distributions and undertaking that such species are at a state of stability. …”
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Elements of organisation of integrated maternity care and their associations with outcomes: a scoping review protocol by Soo Downe, Ank de Jonge, Pim P Valentijn, Suzanne Thompson, Hester Rippen, Corine J M Verhoeven, Jolanda Liebregts, Bahareh Goodarzi, Jan Jaap Erwich, George Burchell, Ronald Batenburg, Eline F de Vries, Irene de Graaf, Puck van Heemstra, Jeroen Struijs, Susanne Zuidhof, Inge Boesveld, Anouk Kaiser, Mirjam Fransen, Durk Berks, Pauline Haga, Katarzyna Burzynska, Joland Vermolen, Lucienne Bakker, Mariëtte Hoogsteder, Lillian Peters, Conny Vreugdehil, Aimée Sparendam-Bruijnincx, Betty de Vries, Elle Struijf, Lillianne van der Velde, Bert Horlings, Marianne Nieuwenhuijze, Marc Roosenboom, Simone Plaizier

“…We will examine which elements of integrated maternity care are associated with maternal and neonatal health outcomes, experiences of women and professionals, healthcare spending and care processes.Methods and analysis We will conduct this review using the JBI methodology for scoping reviews and the reporting guideline PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews). We will undertake a systematic search in the databases PubMed, Scopus, Cochrane and PsycINFO. …”
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Effects of dietary supplementation with milk fat globule membrane on the physical performance of community-dwelling Japanese adults: a randomised, double-blind, placebo-controlled... by Yasuo Kokai, Nana Mikami, Mitsuhiro Tada, Kazuichi Tomonobu, Ryuji Ochiai, Noriko Osaki, Yoshihisa Katsuragi, Hitoshi Sohma, Yoichi M. Ito

“…Measurements of physical performance (without undertaking any mandatory exercise) examining muscle strength, agility and balance were tested every 6 weeks until 24 weeks. …”
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Perception towards Biomedical Research among Undergraduate Medical Students in a Tertiary Care Institute of Kolkata: A Cross-Sectional Study by Sreetama Chakrabarti, Prince Kerketta, Mausumi Basu, Shalini Pattanayak, Somnath Naskar, Dipendra Narayan Goswami

“…It is believed to effectively foster research-oriented thinking among the students, thereby encouraging them to undertake further research activities in future. Objectives: The objectives of this study were to find out the level of perception of undergraduate medical students towards biomedical research, to explore the facilitators and barriers to biomedical research and to identify any associated background information of the students with their perception. …”
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Planning implementation and scale-up of physical activity interventions for people with walking difficulties: study protocol for the process evaluation of the ComeBACK trial by Siobhan Wong, Leanne Hassett, Harriet Koorts, Anne Grunseit, Allison Tong, Anne Tiedemann, Colin J. Greaves, Abby Haynes, Andrew Milat, Lisa A. Harvey, Nicholas F. Taylor, Rana S. Hinman, Marina De Barros Pinherio, Matthew Jennings, Daniel Treacy, Sandra O’Rourke, Courtney West, Elizabeth Ramsay, Catherine Kirkham, Claire Morris, Catherine Sherrington

“…Abstract Background There is currently little evidence of planning for real-world implementation of physical activity interventions. We are undertaking the ComeBACK (Coaching and Exercise for Better Walking) study, a 3-arm hybrid Type 1 randomised controlled trial evaluating a health coaching intervention and a text messaging intervention. …”
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Anakinra Pilot – a clinical trial to demonstrate safety, feasibility and pharmacokinetics of interleukin 1 receptor antagonist in preterm infants by Elys A. Green, Elys A. Green, Elys A. Green, David Metz, David Metz, David Metz, Robert Galinsky, Rebecka Atkinson, Rebecka Atkinson, Elizbeth M. Skuza, Megan Clark, Megan Clark, Alistair J Gunn, Carl M. Kirkpatrick, Rod W. Hunt, Rod W. Hunt, Rod W. Hunt, Philip J. Berger, Claudia A. Nold-Petry, Claudia A. Nold-Petry, Marcel F. Nold, Marcel F. Nold, Marcel F. Nold

“…During the study, there will be a interim analysis to confirm predictions before undertaking dose assessment. Anakinra therapy will be considered safe if the frequency of adverse outcomes/events does not exceed that expected in infants born at 240-276 weeks GA.Clinical Trial Registrationhttps://clinicaltrials.gov/, identifier NCT05280340.…”
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Developing water resiliency solutions at military installations by Clint B. Smith, Damarys Acevedo-Acevedo, Edith Martínez-Guerra, Victor F. Medina, Michael P. Duczynski, Susan R. Wolters, Noah W. Garfinkle, Lauren Melendez, Luisa I. Feliciano

“…An essential component of the IEWP is the development of potential solutions, or courses of action (COAs) to address deficiencies that can improve an installation’s baseline condition, ensuring energy and water (E&W) security and resiliency. The undertaking seeks to improve security and resiliency by considering the varied threats of disruption within installations and providing measures for adaptable recovery. …”
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Protocol for a meta-research study of protocols for diet or nutrition-related trials published in indexed journals: general aspects of study design, rationale and reporting limitat... by Shona Kirtley, Sally Hopewell, Solange Durão, Matthew J Page, Sarah Lamb, Leila Cheikh Ismail, Jonathan Alistair Cook, Cintia Curioni, Neha Khandpur, Gilberto Kac, Gary Stephen Collins, Fabio S Gomes, Flávia Moraes Silva, Amanda Rodrigues Amorim Adegboye, Jennifer A De Beyer, Colby J Vorland, Michael M Schlussel

“…This protocol is registered on the Open Science Framework (DOI: 10.17605/OSF.IO/YWEVS).Ethics and dissemination This study will undertake a secondary analysis of published data and does not require ethical approval. …”
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Strengthening self-regulation and reducing poverty to prevent adolescent depression and anxiety: Rationale, approach and methods of the ALIVE interdisciplinary research collaborati... by Crick Lund, Mark J. D. Jordans, Emily Garman, Ricardo Araya, Mauricio Avendano, Annette Bauer, Vikram Bahure, Tarun Dua, Georgia Eleftheriou, Sara Evans-Lacko, Juan Felipe García Rodríguez, Kamal Gautam, Martin Gevonden, Philipp Hessel, Brandon A. Kohrt, Lydia Krabbendam, Nagendra P. Luitel, Sanchari Roy, Manuel Seifert Bonifaz, Rakesh Singh, Mohammadamin Sinichi, Katherine Sorsdahl, Graham Thornicroft, Wietse A. Tol, Daniela Trujillo, Nicci van der Merwe, Syed Shabab Wahid, Paula Yarrow

“…Methods This aim will be achieved by addressing four objectives: (1) develop a conceptual framework that identifies the causal mechanisms linking poverty, self-regulation and depression and anxiety; (2) develop a multi-component selective prevention intervention targeting self-regulation and poverty among adolescents at high risk of developing depression or anxiety; (3) adapt and validate instruments to measure incidence of depression and anxiety, mediators and implementation parameters of the prevention intervention; and (4) undertake a four-arm pilot cluster randomised controlled trial to assess the feasibility, acceptability and cost of the selective prevention intervention in the three study sites. …”
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Adapting population health interventions for new contexts: qualitative interviews understanding the experiences, practices and challenges of researchers, funders and journal editor... by Graham Moore, Pat Hoddinott, Rhiannon E Evans, Simon Murphy, Jeremy Segrott, Lauren Copeland, Hannah J Littlecott, Danielle Couturiaux

“…Nevertheless, there remains limited exploration of the real-world experiences of undertaking intervention adaptation, notably the challenges encountered by different groups of stakeholders, and how these are managed. …”
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Early Results from GLASS-JWST. XV. Properties of the Faintest Red Sources in the NIRCAM Deep Fields by K. Glazebrook, T. Nanayakkara, C. Jacobs, N. Leethochawalit, A. Calabrò, A. Bonchi, M. Castellano, A. Fontana, C. Mason, E. Merlin, T. Morishita, D. Paris, M. Trenti, T. Treu, P. Santini, X. Wang, K. Boyett, Marusa Bradac, G. Brammer, T. Jones, D. Marchesini, M. Nonino, B. Vulcani

“…We present a first look at the reddest 2–5 μ m sources found in deep images from the GLASS Early Release Science program. We undertake a general search, i.e., not looking for any particular spectral signatures, for sources detected only in bands redder than is reachable with the Hubble Space Telescope, and which would likely not have been identified in pre-JWST surveys. …”
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Results and Clinical Interpretation of Germline <i>RET</i> Analysis in a Series of Patients with Medullary Thyroid Carcinoma: The Challenge of the Variants of Uncertain Significanc... by Giovanni Innella, Cesare Rossi, Maria Romagnoli, Andrea Repaci, Davide Bianchi, Maria Elena Cantarini, Davide Martorana, Lea Godino, Andrea Pession, Antonio Percesepe, Uberto Pagotto, Daniela Turchetti

“…Subsequent target testing in relatives allowed us to identify 22 asymptomatic carriers, who could undertake appropriate screening. Overall, patients with germline <i>RET</i> variants differed significantly from those who tested negative by family history (<i>p</i> < 0.001) and mean age at MTC diagnosis (44.45 vs. 56.42 years; <i>p</i> = 0.010), but the difference was not significant when only carriers of moderate risk variants were considered (51.78 vs. 56.42 years; <i>p</i> = 0.281). …”
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Natural, synthetic, and composite materials for industrial effluents treatment: A mini review on current practices, cost-effectiveness, and sustainability by Shehu Sa'ad Abdullahi, Rania Edrees Adam Mohammad, Ahmad Hussaini Jagaba, Haruna Musa, Abdullahi Haruna Birniwa

“…By shedding light on the environmental consequences of these activities, the research aims to fill existing knowledge gaps, urging the scientific community to undertake further investigations. In conclusion, this work contributes to the ongoing dialogue on creative solutions for industrial effluent treatment, ensuring a balance between environmental preservation and economic viability.…”
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In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, Akt and p38 MAP kinase in L6 cells by Jayesh Mudgal, Priya Shetty, Neetinkumar D Reddy, Akhila H.S., Karthik Gourishetti, Geetha Mathew, Pawan Ganesh Nayak, Nitesh Kumar, Anoop Kishore, Nampurath Gopalan Kutty, Krishnadas Nandakumar, Rekha Raghuveer Shenoy, Chamallamudi Mallikarjuna Rao, Alex Joseph

“…However, due to the limitations of the STZ model, we decided to undertake a detailed evaluation of anti-diabetic potential of the molecules on a high sucrose diet (HSD) fed diabetic mouse model. …”
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Transradial intra-aortic catheter looping in the angioplasty of severe intracranial symptomatic arteriosclerotic diseases by Gang-Qin Xu, Gang-Qin Xu, Gang-Qin Xu, Jin-Chao Xia, Jin-Chao Xia, Jin-Chao Xia, Dong-Yang Cai, Dong-Yang Cai, Dong-Yang Cai, Bo-Wen Yang, Bo-Wen Yang, Bo-Wen Yang, Tong-Yuan Zhao, Tong-Yuan Zhao, Tong-Yuan Zhao, Jiang-Yu Xue, Jiang-Yu Xue, Jiang-Yu Xue, Zi-Liang Wang, Zi-Liang Wang, Zi-Liang Wang, Tian-Xiao Li, Tian-Xiao Li, Tian-Xiao Li, Bu-Lang Gao, Bu-Lang Gao, Bu-Lang Gao

“…In the follow-up angiography conducted on 10 (66.7%) patients after 6–25 months, no in-stent restenosis was detected.ConclusionIntra-aortic guiding catheter looping via transradial access for endovascular angioplasty of SISOLAs is technically safe, feasible, and effective, especially when the transfemoral artery approach is difficult or impossible to undertake.…”
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