Youth violence intervention programme for vulnerable young people attending emergency departments in London: a rapid evaluation by Appleby John, Georghiou Theo, Ledger Jean, Rolewicz Lucina, Sherlaw-Johnson Chris, Tomini Sonila M, Frerich Jason M, Ng Pei Li

“…If we were able to establish during phase 1 that it would be possible to undertake a quantitative evaluation of the impact of service, then this would have been included in phase 2 alongside a cost-effectiveness analysis (CEA). …”
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Exploring the relationship between working from home, mental and physical health and wellbeing: a systematic review by Blank Lindsay, Hock Emma, Cantrell Anna, Baxter Susan, Goyder Elizabeth

“…Papers which look at students, and those studying, rather than undertaking paid employment at home, were excluded from this review. …”
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Antibiotics for lower respiratory tract infection in children presenting in primary care: ARTIC-PC RCT by Little Paul, Francis Nick A, Stuart Beth, O’Reilly Gilly, Thompson Natalie, Becque Taeko, Hay Alastair D, Wang Kay, Sharland Michael, Harnden Anthony, Yao Guiqing, Raftery James, Zhu Shihua, Little Joseph, Hookham Charlotte, Rowley Kate, Euden Joanne, Harman Kim, Coenen Samuel, Read Robert C, Woods Catherine, Butler Christopher C, Faust Saul N, Leydon Geraldine, Wan Mandy, Hood Kerenza, Whitehurst Jane, Richards-Hall Samantha, Smith Peter, Thomas Michael, Moore Michael, Verheij Theo

“…Objective The objective was to undertake a trial of antibiotics for children presenting with lower respiratory tract infection in primary care, with a parallel observational study. …”
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Eye donation from palliative and hospice care contexts: the EDiPPPP mixed-methods study by Tracy Long-Sutehall, Mike Bracher, Sarah Mollart, Jane Wale

“…Design A 36-month mixed-methods, multicentre study undertaking three work packages. Settings Three hospice care and three hospital-based palliative care services situated in the North, Midlands and the South of England (one service of each type per region). …”
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Ondansetron for irritable bowel syndrome with diarrhoea: randomised controlled trial by David Gunn, Rabia Topan, Ron Fried, Ivana Holloway, Richard Brindle, Suzanne Hartley, Lorna Barnard, Maura Corsetti, S Mark Scott, Adam Farmer, Ayesha Akbar, Maria Eugenicos, Nigel Trudgill, Kapil Kapur, John McLaughlin, David S Sanders, Arvind Ramadas, Peter Whorwell, Lesley Houghton, Phil G Dinning, Qasim Aziz, Alexander C Ford, Amanda Farrin, Robin Spiller

“…Conclusion Our results are consistent with previous studies and confirmed ondansetron improves stool consistency and urgency but showed minor effect on pain. We plan to undertake a simplified version of this trial overcoming the changed referral pathways by recruiting in primary care, using software linked to primary care records to identify and randomise patients with irritable bowel syndrome with diarrhoea to ondansetron or placebo and remotely follow their progress; thus minimising barriers to recruitment. …”
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Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation by Chris Hollis, Charlotte L Hall, Kareem Khan, Marie Le Novere, Louise Marston, Rebecca Jones, Rachael Hunter, Beverley J Brown, Charlotte Sanderson, Per Andrén, Sophie D Bennett, Liam R Chamberlain, E Bethan Davies, Amber Evans, Natalia Kouzoupi, Caitlin McKenzie, Isobel Heyman, Joseph Kilgariff, Cristine Glazebrook, David Mataix-Cols, Eva Serlachius, Elizabeth Murray, Tara Murphy

“…Secondary objectives included (1) optimising the design of the intervention, (2) undertaking an internal pilot, (3) evaluating cost-effectiveness, (4) establishing whether the efficacy is maintained longer term, (5) understanding the mechanisms of impact of the intervention and (6) identifying barriers to implementation. …”
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The History of Medical Ethics in India by Angel Prabakar

“…While industry and government leaders are trying to solve the multi-faceted issues facing the medical industry, it is obvious that this is an undertaking requiring inventive solutions. Prioritizing ethics in medical education, de-privatizing medical schools and hospitals, offering affordable options, and limiting corruption would improve India’s ability to offer high-quality medical care. …”
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Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT by Matthew J Ridd, Sian Wells, Stephanie J MacNeill, Emily Sanderson, Douglas Webb, Jonathan Banks, Eileen Sutton, Alison RG Shaw, Zoe Wilkins, Julie Clayton, Amanda Roberts, Kirsty Garfield, Lyn Liddiard, Tiffany J Barrett, J Athene Lane, Helen Baxter, Laura Howells, Jodi Taylor, Alastair D Hay, Hywel C Williams, Kim S Thomas, Miriam Santer

“…A total of 95% of participants provided at least one post-baseline POEM score and, therefore, were included in the primary outcome analysis. The researcher undertaking the EASI assessment identified the correct allocation in seven participants. …”
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Impact of interventions to improve recovery of older adults following planned hospital admission on quality-of-life following discharge: linked-evidence synthesis by Debbie Kinsey, Samantha Febrey, Simon Briscoe, Dylan Kneale, Jo Thompson Coon, Daniele Carrieri, Christopher Lovegrove, John McGrath, Anthony Hemsley, GJ Melendez-Torres, Liz Shaw, Michael Nunns

“…We then developed revised truth tables, having taken a logical and considered approach to the studies and characteristics that were included and excluded from revised tables. After undertaking essential quality checks, we used our knowledge of the evidence base and discussions with stakeholders to interpret the solution. …”
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Work Floor Experiences of Supply Chain Partnering in the Dutch Housing Sector by Marieke Venselaar

“…Again, this is a matter of attitude, rather than undertaking extra actions. There are different ways to achieve this. …”
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A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation by Ratna Sohanpal, Hilary Pinnock, Liz Steed, Karen Heslop-Marshall, Moira J Kelly, Claire Chan, Vari Wileman, Amy Barradell, Clarisse Dibao-Dina, Paulino Font Gilabert, Andy Healey, Richard Hooper, Kristie-Marie Mammoliti, Stefan Priebe, Mike Roberts, Vickie Rowland, Sarah Waseem, Sally Singh, Melanie Smuk, Martin Underwood, Patrick White, Nahel Yaziji, Stephanie JC Taylor

“…Specific objectives To develop and refine the TANDEM intervention to develop a training programme for healthcare professionals who will deliver the programme, and to document the training programme in a manual. To undertake a randomised controlled trial of the TANDEM intervention to examine the effectiveness of the TANDEM intervention on clinical outcomes compared with usual care (i.e. guideline-defined care, including the offer of PR). …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“….; Kim, M.K., et al., “The International Xenotransplantation Association Consensus Statement on Conditions for Undertaking Clinical Trials of Xenocorneal Transplantation,” Xenotransplantation 21, no. 5 (2014): 420-30. …”
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Peer support for discharge from inpatient to community mental health care: the ENRICH research programme by Steve Gillard, Rhiannon Foster, Sarah White, Andrew Healey, Stephen Bremner, Sarah Gibson, Lucy Goldsmith, Mike Lucock, Jacqueline Marks, Rosaleen Morshead, Akshaykumar Patel, Shalini Patel, Julie Repper, Miles Rinaldi, Alan Simpson, Michael Ussher, Jessica Worner, Stefan Priebe

“…The research team included: two experienced service user researchers who oversaw patient and public involvement; service user researchers employed to develop and undertake data collection and analysis; a Lived Experience Advisory Group that informed all stages of the research. …”
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Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs by Foster Nadine E, Dunn Kate M, Protheroe Joanne, Hill Jonathan C, Lewis Martyn, Saunders Benjamin, Jowett Sue, Hennings Susie, Campbell Paul, Bromley Kieran, Bartlam Bernadette, Babatunde Opeyemi, Wathall Simon, Oppong Raymond, Kigozi Jesse, Chudyk Adrian

“…•on the clinical effectiveness and cost-effectiveness of stratified primary care compared with usual care (usual care) – ◦determine the comparative clinical effectiveness of stratified care versus usual primary care for patient outcomes ◦investigate GP fidelity to delivery of stratified care and the impact on clinical decision-making ◦undertake an economic evaluation of stratified care versus usual care ◦conduct a nested qualitative study to understand how stratified care was perceived and operationalised by clinicians and patients. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“….; Kim, M.K., et al., “The International Xenotransplantation Association Consensus Statement on Conditions for Undertaking Clinical Trials of Xenocorneal Transplantation,” Xenotransplantation 21, no. 5 (2014): 420-30. …”
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Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT by Wenborn Jennifer, Mountain Gail, Moniz-Cook Esme, Poland Fiona, King Michael, Omar Rumana, O’Keeffe Aidan, Morris Stephen, Pizzo Elena, Michie Susan, Vernooij-Dassen Myrra, Graff Maud, Hill Jane, Challis David, Russell Ian, Sackley Catherine, Hynes Sinéad, Crellin Nadia, Mundy Jacqueline, Burgess Jane, Swinson Tom, Di Bona Laura, Field Becky, Hart Cathryn, Stansfeld Jacki, Walton Holly, Rooks Sally, Ledgerd Ritchard, Orrell Martin

“…We embedded two qualitative studies within the trial: •We explored the experience of undertaking the COTiD-UK intervention from the perspective of people with dementia, family carers and occupational therapists. …”
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A‌S‌S‌E‌S‌S‌M‌E‌N‌T O‌F E‌F‌F‌E‌C‌T O‌F I‌N‌I‌T‌I‌A‌L O‌U‌T-O‌F-P‌L‌U‌M‌B‌N‌E‌S‌S I‌M‌P‌E‌R‌F‌E‌C‌T‌I‌O‌N O‌F C‌O‌L‌U‌M‌N‌S O‌N T‌H‌E B‌E‌H‌A‌V‌I‌O‌R O‌F 2D B‌E‌N‌D‌I‌N‌G S‌T‌E‌E‌L... by M. G‌e‌r‌a‌m‌i, V. E‌g‌h‌t‌e‌s‌a‌d‌i

“…S‌o‌m‌e S‌o‌f‌t‌w‌a‌r‌e h‌a‌s t‌h‌e a‌b‌i‌l‌i‌t‌y t‌o u‌n‌d‌e‌r‌t‌a‌k‌e t‌h‌e a‌n‌a‌l‌y‌s‌i‌s, a‌c‌c‌u‌r‌a‌t‌e‌l‌y. …”
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