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Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough
Published 2022-09-01Subjects: Get full text
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203
Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models
Published 2023-01-01Subjects: Get full text
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204
A reengineered common chain cytokine augments CD8+ T cell–dependent immunotherapy
Published 2022-05-01Subjects: Get full text
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205
An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma
Published 2022-08-01Subjects: Get full text
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206
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target
Published 2022-11-01Subjects: Get full text
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207
Gene therapy with a synthetic adeno-associated viral vector improves audiovestibular phenotypes in Pjvk-mutant mice
Published 2022-10-01Subjects: Get full text
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208
E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects
Published 2021-12-01Subjects: Get full text
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209
Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice
Published 2023-07-01Subjects: Get full text
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210
Viral vector–mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome
Published 2023-06-01Subjects: Get full text
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211
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
Published 2022-10-01Subjects: Get full text
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212
Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease
Published 2022-12-01Subjects: Get full text
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213
Ablation of T cell–associated PD-1H enhances functionality and promotes adoptive immunotherapy
Published 2022-01-01Subjects: Get full text
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214
Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation
Published 2022-09-01Subjects: Get full text
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215
HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis
Published 2022-09-01Subjects: Get full text
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216
Anti-CD45RC antibody immunotherapy prevents and treats experimental autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy syndrome
Published 2022-04-01Subjects: Get full text
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217
SLC26A6-selective inhibitor identified in a small-molecule screen blocks fluid absorption in small intestine
Published 2021-06-01Subjects: Get full text
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218
Modulation of the effects of class Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits
Published 2021-08-01Subjects: Get full text
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219
Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma
Published 2022-07-01Subjects: Get full text
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220
Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition
Published 2023-04-01Subjects: Get full text
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