A Comparative Antibacterial, Antioxidant, and Antineoplastic Potential of <i>Rauwolfia serpentina</i> (L.) Leaf Extract with Its Biologically Synthesized Gold Nanoparticles (R-AuNP... by Mohammad Y. Alshahrani, Zeeshan Rafi, Nadiyah M. Alabdallah, Ambreen Shoaib, Irfan Ahmad, Mohammed Asiri, Gaffar Sarwar Zaman, Shadma Wahab, Mohd Saeed, Salman Khan

“…Subsequently, the findings of this study indicated that <i>R. serpentina</i> leaves and their nanoformulation can be used as a potent source for the treatment of the above-mentioned complications and can be used as a possible agent for novel target-based therapies for the management of different ailments.…”
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The management of retroperitoneal sarcoma: The experience of a single institution and a review of the literature by Jihene Feki, MD, Maissa Lajnef, MD, Mohamed Fourati, MD, Dhouha Sakka, MD, Rania B. Hassena, MD, Mourad H. Slimen, MD, Jamel Daoud, MD, Afef Khanfir, MD

“…Further prospective trials are warranted to select optimal therapies with less toxicity and better efficacy in reducing recurrences, mainly at a local level.…”
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Traditional Chinese medicine Master XIONG Jibo’s medication experience in treating arthralgia syndrome through data mining by Deng Wenxiang, Zhang Jidong, Zhang Wenan, He Qinghu

“…Conclusion: Clearing heat and dampness, relieving collaterals and pain, and invigorating Qi and blood are the most commonly used therapies for the treatment of AS by Professor XIONG Jibo. …”
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Terapias Biológicas en Artritis Reumatoide: Análisis coste-efectividad de las alternativas terapéuticas by Ana Fernández Pérez, Natalia Pérez Rodríguez, Santiago Piñeiro Conde, Inmaculada López Rodríguez, Victor López García

“…Objective: Cost-effectiveness of alternative therapies included in the Central Autonomous Committee Pharmacy and Therapeutics protocol for Rheumatoid Arthritis treatment. …”
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Achados histopatológicos renais em idosos Histopathological findings in elderly patients by Priscylla Aparecida Vieira do Carmo, Gianna Mastroianni Kirsztajn, Wander Barros do Carmo, Marcello Fabiano Franco, Marcus Gomes Bastos

“…Similarly to other comorbidities, glomerular diseases are also observed in the elderly, and, in that age group, kidney biopsy emerges as a fundamental diagnostic tool to help disease management, preventing unnecessary therapies. OBJECTIVE: To establish the frequency of histological diagnoses in the elderly undergoing kidney biopsy, with an emphasis on glomerulopathies (GPs), at two Brazilian universities. …”
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Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon by Andreas Walter, Perrine Paul-Gilloteaux, Perrine Paul-Gilloteaux, Birgit Plochberger, Ludek Sefc, Paul Verkade, Julia G. Mannheim, Julia G. Mannheim, Julia G. Mannheim, Paul Slezak, Angelika Unterhuber, Martina Marchetti-Deschmann, Manfred Ogris, Katja Bühler, Dror Fixler, Stefan H. Geyer, Wolfgang J. Weninger, Martin Glösmann, Stephan Handschuh, Thomas Wanek

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Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT by Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson

“…The heterogenous cohort of patients with ARDS was an attempt to ensure that our findings would be generalisable; however, it may be more appropriate to target potential therapies based on their proposed biological mechanism for a specific population of patients. …”
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Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients by Riuko Ohashi, Hajime Umezu, Ayako Sato, Tatsuya Abé, Shuhei Kondo, Kenji Daigo, Seijiro Sato, Norikazu Hara, Akinori Miyashita, Takeshi Ikeuchi, Teiichi Motoyama, Masashi Kishi, Tadahiro Nagaoka, Keiko Horiuchi, Atsushi Shiga, Shujiro Okuda, Tomoki Sekiya, Aya Ohtsubo, Kosuke Ichikawa, Hiroshi Kagamu, Toshiaki Kikuchi, Satoshi Watanabe, Jun-Ichi Tanuma, Peter Schraml, Takao Hamakubo, Masanori Tsuchida, Yoichi Ajioka

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Assessing the Sealing Performance and Clinical Outcomes of Endodontic Treatment in Patients with Chronic Apical Periodontitis Using Epoxy Resin and Calcium Salicylate Seals by Razvan Mihai Horhat, Bogdan Andrei Bumbu, Laura Orel, Oana Velea-Barta, Laura Cirligeriu, Gratiana Nicoleta Chicin, Marius Pricop, Mircea Rivis, Stefania Dinu, Delia Ioana Horhat, Felix Bratosin, Roxana Manuela Fericean, Rodica Anamaria Negrean, Luminita Maria Nica

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CINSARC in high‐risk soft tissue sarcoma patients treated with neoadjuvant chemotherapy: Results from the ISG‐STS 1001 study by Anna Maria Frezza, Silvia Stacchiotti, Frederic Chibon, Jean‐Michelle Coindre, Antoine Italiano, Cleofe Romagnosa, Silvia Bagué, Angelo Paolo Dei Tos, Luca Braglia, Emanuela Palmerini, Vittorio Quagliuolo, Javier Martin Broto, Antonio Lopez Pousa, Giovanni Grignani, Antonella Brunello, Jean‐Yves Blay, Robert Diaz Beveridge, Iwona Lugowska, Tom Lesluyes, Roberta Maestro, Franco Domenico Merlo, Paolo Giovanni Casali, Alessandro Gronchi

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Chloroquine and Hydroxychloroquine for the Prevention and Treatment of COVID-19: A Fiction, Hope or Hype? An Updated Review by Saghir SAM, AlGabri NA, Alagawany MM, Attia YA, Alyileili SR, Elnesr SS, Shafi ME, Al-shargi OYA, Al-balagi N, Alwajeeh AS, Alsalahi OS, Patra AK, Khafaga AF, Negida A, Noreldin A, Al-Amarat W, Almaiman AA, El-Tarabily KA, Abd El-Hack ME

“…With the dawn of this novel coronavirus (SARS-CoV-2), there was a requirement to select potential therapies that might effectively kill the virus, accelerate the recovery, or decrease the case fatality rate. …”
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Noninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis by Yulin Sun, Zhengguang Guo, Xiaoyan Liu, Lijun Yang, Zongpan Jing, Meng Cai, Zhaoxu Zheng, Chen Shao, Yefan Zhang, Haidan Sun, Li Wang, Minjie Wang, Jun Li, Lusong Tian, Yue Han, Shuangmei Zou, Jiajia Gao, Yan Zhao, Peng Nan, Xiufeng Xie, Fang Liu, Lanping Zhou, Wei Sun, Xiaohang Zhao

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The clinical effectiveness and cost-effectiveness of management strategies for sciatica: systematic review and economic model by R Lewis, N Williams, HE Matar, N Din, D Fitzsimmons, C Phillips, M Jones, A Sutton, K Burton, S Nafees, M Hendry, I Rickard, R Chakraverty, C Wilkinson

“…Conclusions: These findings provide support for the effectiveness of currently used therapies for sciatica such as non-opioid medication, epidural corticosteroid injections and disc surgery, but also for chemonucleolysis, which is no longer used in the UK NHS. …”
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DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts by Amy J. Lynham, Sarah Knott, Jack F. G. Underwood, Leon Hubbard, Sharifah S. Agha, Jonathan I. Bisson, Marianne B. M. van den Bree, Samuel J. R. A. Chawner, Nicholas Craddock, Michael O'Donovan, Ian R. Jones, George Kirov, Kate Langley, Joanna Martin, Frances Rice, Neil P. Roberts, Anita Thapar, Richard Anney, Michael J. Owen, Jeremy Hall, Antonio F. Pardiñas, James T. R. Walters

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Influence of diabetes on sacubitril/valsartan titration and clinical outcomes in patients hospitalized for heart failure by Klaus K. Witte, Rolf Wachter, Michele Senni, Jan Belohlavek, Ewa Straburzynska‐Migaj, Candida Fonseca, Eva Lonn, Adele Noè, Heike Schwende, Dmytro Butylin, YannTong Chiang, Domingo Pascual‐Figal, the TRANSITION investigators

“…Abstract Aims Diabetes mellitus is associated with worse outcomes and lower attainment of disease‐modifying therapies in patients with heart failure with reduced ejection fraction (HFrEF). …”
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Hipertensão arterial pulmonar â Experiência do Centro Hospitalar de Vila Nova de Gaia by Ana Oliveira, Daniela Ferreira, António Caiado, Susana Ferreira, Paula Ferreira, Lino Santos, Manuel Gonçalves, Teresa Shiang

“…Five patients recovered, three are stable, one worsened and two died.Conclusions: PAH is a serious illness which requires a multidisciplinary approach with the need for complex and expensive therapies. Diagnosis in initial stages is essential for an effective treatment.Rev Port Pneumol 2007; XIII (2): 239-254…”
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La «Semana del Fósforo»: implicación de la nefrología española en el control de los valores plasmáticos de fósforo by Emilio Sánchez Álvarez, Marc Xipell, Anna Gallardo, Elena Astudillo, Jose-Vicente Torregrosa

“…Methods: All members of the Spanish Society of Nephrology were invited to participate in an online survey, which included questions on aspects related to phosphorus control in patients with advanced CKD (aCKD) (glomerular filtration rate <30 ml/min/1.73 m2) and in the different modalities of renal replacement therapies (peritoneal dialysis [PD], hemodialysis [HD] and renal transplantation [KT]). …”
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Efficacy of two siddha polyherbal decoctions, Nilavembu Kudineer and Kaba Sura Kudineer, along with standard allopathy treatment in the management of mild to moderate symptomatic C... by Anurag Srivastava, Manickavasagam Rengaraju, Saurabh Srivastava, Vimal Narayanan, Vivek Gupta, Rashmi Upadhayay, Jitender Kumar, Sathiyarajeswaran Parameswaran, KanakavalliKadarkarai, AarthiVelmurugan

“…Indian traditional medicines, especially polyherbal formulations like Nilavembu Kudineer (NVK) and Kaba Sura Kudineer (KSK) of the Siddha system of medicine, have been used as public health interventions for controlling viral epidemics like dengue and Chikungunya. These traditional therapies have been found safe, effective, and widely accepted. …”
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Expressão fenotípica da miocardiopatia hipertrófica e realce tardio na ressonância magnética cardíaca by Francisca Caetano, Ana Botelho, Joana Trigo, Joana Silva, Inês Almeida, Margarida Venâncio, João Pais, Conceição Sanches, António Leitão Marques

“…At follow‐up, no differences were found in the frequency of ventricular arrhythmias, appropriate ICD therapies or mortality. Conclusions: The presence of LGE emerges as a risk marker, associated with the classical predictors of sudden cardiac death in this population. …”
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Identificação molecular pelo método de Spoligotyping de estirpes do complexo Mycobacterium tuberculosis isoladas no Hospital Fernando Fonseca by Suzana David, Clara Portugal, Abílio Antunes, Ãngela Cardoso, Ana Calado, Barros Vanessa, Luísa Sancho

“…In Europe, this infection is extremely rare suggesting the result may not be due to M. bovis infection but to M. bovis BCG (due to vaccination or eventual recombinant BCG based therapies), or M. africanum (due to the proximity of the two species).A high percentage of the Spoligotypes were not identified by the database, 21.4 %.This is the first study of this type amongst us and may be the starting point for the creation of a data base with important consequences on the national program against tuberculosis.REV PORT PNEUMOL 2004; X (3): 195-204 Palavras-chave: Complexo Mycobacterium tuberculosis, Spoligotyping, Portugal, Key-words: Mycobacterium tuberculosis complex, Spoligotyping, Portugal…”
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