Studying TIGIT activity against tumors through the generation of knockout mice by Ahmed Rishiq, Reem Bsoul, Ophir Pick, Ofer Mandelboim

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Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity by Alyson J. Smith, Robert E. Thurman, Weiping Zeng, Bryan Grogan, Sasha Lucas, Guadalupe Gutierrez, Ryan A. Heiser, Serena W. Wo, Amber Blackmarr, Scott Peterson, Shyra J. Gardai

Subjects: “…TIGIT…”
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Targeting TIGIT for Immunotherapy of Cancer: Update on Clinical Development by Anand Rotte, Srikumar Sahasranaman, Nageshwar Budha

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CD8+ T-cells Co-expressing PD-1 and TIGIT Are Highly Frequent in Chronic Lymphocytic Leukemia by Reza Hajiasghar-Sharbaf, Hossein Asgarian-Omran, Reza Valadan, Hadi Hossein-Nattaj, Ramin Shekarriz, Ehsan Zaboli, Ghasem Janbabaei, Mohsen Tehrani

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Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer by Hauke Stamm, Leticia Oliveira-Ferrer, Eva-Maria Grossjohann, Jana Muschhammer, Vanessa Thaden, Franziska Brauneck, Roman Kischel, Volkmar Müller, Carsten Bokemeyer, Walter Fiedler, Jasmin Wellbrock

Subjects: “…tigit…”
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Expression of TIGIT in splenic and circulatory T cells from mice acutely infected with Toxoplasma gondii by Wang Shuai, Li Haoran, Zhang Fuqiang, Jiao Yuankai, Xie Qing, Zhang Zhenchao, Li Xiangrui

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Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients by Cui Li, Haiyan Liu, Zhongliang Duan

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TIGIT/CD47 dual high expression predicts prognosis and is associated with immunotherapy response in lung squamous cell carcinoma by Yue Peng, Bin Qiu, Fengwei Tan, Jiachen Xu, Fenglong Bie, Huayu He, Lei Liu, He Tian, Guangyu Bai, Bolun Zhou, Yuan Li, Qilin Huai, Zhenlin Yang, Shugeng Gao

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TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular CarcinomaSummary by Zhouhong Ge, Guoying Zhou, Lucia Campos Carrascosa, Erik Gausvik, Patrick P.C. Boor, Lisanne Noordam, Michael Doukas, Wojciech G. Polak, Türkan Terkivatan, Qiuwei Pan, R. Bart Takkenberg, Joanne Verheij, Joris I. Erdmann, Jan N.M. IJzermans, Maikel P. Peppelenbosch, Jaco Kraan, Jaap Kwekkeboom, Dave Sprengers

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Combining TIGIT blockade with IL‐15 stimulation is a promising immunotherapy strategy for lung adenocarcinoma by Baohong Luo, Yu Sun, Qinru Zhan, Yuting Luo, Yu Chen, Tongze Fu, Tiantian Yang, Lijuan Ren, Zhongpeng Xie, Xiaohua Situ, Bixia Liu, Kejing Tang, Zunfu Ke

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TIGIT enhances CD4+ regulatory T‐cell response and mediates immune suppression in a murine ovarian cancer model by Fengzhen Chen, Yanying Xu, Yulong Chen, Shu Shan

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ImmunoPET imaging of TIGIT in the glioma microenvironment by Sarah R. Vincze, Ambika P. Jaswal, Stephen C. Frederico, Michal Nisnboym, Bo Li, Zujian Xiong, ReidAnn E. Sever, Chaim T. Sneiderman, Mikayla Rodgers, Kathryn E. Day, Joseph D. Latoche, Lesley M. Foley, T. Kevin Hitchens, Robin Frederick, Ravi B. Patel, Costas G. Hadjipanayis, Itay Raphael, Jessie R. Nedrow, W. Barry Edwards, Gary Kohanbash

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Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential by Yue Wang, Yidi Li, Jiaqi Chen, Chenxi Guo, Xiaowen Yu, Zining Zhang, Yajing Fu, Xiaoxu Han, Qinghai Hu, Haibo Ding, Hong Shang, Yongjun Jiang

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Expression of the immune checkpoint receptor TIGIT in Hodgkin’s lymphoma by Wenchao Li, Niclas C. Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Björn Wellge, Tim Mandelkow, Nicolaus F. Debatin, Laura Pott, Doris Höflmayer, Maximilian Lennartz, Guido Sauter, Jakob R. Izbicki, Sarah Minner, Franziska Büscheck, Ria Uhlig, David Dum, Till Krech, Andreas M. Luebke, Corinna Wittmer, Frank Jacobsen, Eike Burandt, Stefan Steurer, Waldemar Wilczak, Andrea Hinsch

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Tiragolumab (Anti-TIGIT) in SCLC: Skyscraper-02, a Towering Inferno by Brazel D, Ou SI, Nagasaka M

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Higher TIGIT+ γδ TCM cells may predict poor prognosis in younger adult patients with non-acute promyelocytic AML by Qi Hou, Penglin Wang, Xueting Kong, Xueting Kong, Junjie Chen, Chao Yao, Xiaodan Luo, Yangqiu Li, Yangqiu Li, Zhenyi Jin, Zhenyi Jin, Xiuli Wu, Xiuli Wu

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TIGIT+ CD4+ regulatory T cells enhance PD-1 expression on CD8+ T cells and promote tumor growth in a murine ovarian cancer model by Fengzhen Chen, Yanying Xu, Xiangyu Liu, Na Dong, Lei Tian

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Nectin Family Ligands Trigger Immune Effector Functions in Health and Autoimmunity by Doryssa Hermans, Lisa van Beers, Bieke Broux

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Dynamic Expressions of TIGIT on Splenic T Cells and TIGIT-Mediated Splenic T Cell Dysfunction of Mice With Chronic Toxoplasma gondii Infection by Haoran Li, Jing Zhang, Changwei Su, Xiaowei Tian, Xuefang Mei, Zhenchao Zhang, Mingyong Wang, Xiangrui Li, Xiangrui Li, Shuai Wang

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Self-delivery of TIGIT-blocking scFv enhances CAR-T immunotherapy in solid tumors by Fan Yang, Fan Zhang, Feng Ji, Jiannan Chen, Jun Li, Zhengliang Chen, Zhigang Hu, Zhigang Guo

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