-
7621
Dissecting the upstream regulation of the GATA genes during heart development
Published 2019“…</p> <p>Future experiments will involve ChIP-Seq to test the direct interactions suggested by binding site perturbation studies, and Capture-C to investigate topologically associating domains, ultimately revealing the functional interaction between these enhancers and their regulated GATA genes. …”
Thesis -
7622
Quantum dynamics in mesoscopic magnetism
Published 1998“…These effects occur in ferro- and antiferromagnets due to the presence of a topological spin phase. For antiferromagnetic chains, this spin phase occurs in addition to the Pontryagin-index phase. …”
Conference item -
7623
Zeolite frameworks with beta-cages
Published 2015“…<p>This study focuses on five zeolites: sodalite, zeolite A, linde type N, zeolite Y, and EMC-2, with SOD, LTA, LTN, FAU, and EMT framework topologies respectively. All of these zeolites have β-cages as the framework building units. …”
Thesis -
7624
Integration and segregation in whole-brain networks: implications for altered states of consciousness
Published 2018“…</p> <p>In Chapter 2, I implement a novel method for identifying highly integrative nodes in human brain networks from the persistent homology of fMRI data, as a complement to standard graph theoretical methods. I report that topologically central nodes in the ‘persistence homological scaffold’ have a combination of high betweenness-centrality and high participation coefficient, whilst simultaneously avoiding densely connected neighborhood clusters.…”
Thesis -
7625
Machine learning approaches for computer aided drug discovery
Published 2022“…I explored different topological fingerprint and autoencoder representations for Bayesian optimisation (BO) and showed that BO is a powerful tool to help medicinal chemists to prioritise which new compounds to make for single-target as well as multi-target optimisation. …”
Thesis -
7626
Calabi-Yau manifolds, discrete symmetries and string theory
Published 2017“…</p> <p>Knowledge of the topological properties of the internal space is vital in determining the suitability of the space for realistic string compactifications. …”
Thesis -
7627
NMR studies of the dynamics and the folding of hen lysozyme
Published 1994“…</p> <p>Preliminary structure calculations suggest that, despite the absence of extensive and persistent tertiary interactions, topological restraints exist in parts of the TFE denatured state, resulting in considerable propensities for native-like arrangements of the secondary structure. …”
Thesis -
7628
Processing, structure and properties of Al-matrix composites
Published 2013“…By using a substrate with multi-scale topological features, an ultra-thick (>2mm) deposit was successfully sprayed, which was subsequently consolidated by hot rolling to reduce residual porosity. …”
Thesis -
7629
Mathematical models of the carding process
Published 2001“…The aerodynamic forces overwhelm the fibre's ability to retain its crimp or natural curvature, and so the fibre is treated as an inextensible string. Two machine topologies are studied in detail, thin annular regions with hooked surfaces and the nip region between two rotating drums. …”
Thesis -
7630
Subunit architecture of intact protein complexes from mass spectrometry and homology modeling.
Published 2008“…By studying intact complexes, we show that we are able to not only determine the stoichiometry of all subunits present but also deduce interaction maps and topological arrangements of subunits. To construct an interaction network, we use tandem mass spectrometry to define peripheral subunits and partial denaturation in solution to generate series of subcomplexes. …”
Journal article -
7631
Quantum magnets with strong spin-orbit interaction probed via neutron and x-ray scattering
Published 2014“…The ordering wavevector of both β- and γ-Li<sub>2</sub>IrO<sub>3</sub> polytypes are found to be identical, suggesting that the same magnetic interactions are responsible for stabilizing magnetic order in both materials, despite their different lattice topologies. Following this, the spinel FeSc<sub>2</sub>S<sub>4</sub> is considered. …”
Thesis -
7632
Informed modeling of disorder
Published 2018“…</p> <p>Next, a system of unique topological disorder is considered. Total scattering data are combined with rigid local constraints to develop the first ever squareplanar continuous random network (CRN), which is subsequently used to model an amorphous Pd/Pt(im)<sub>2</sub> phase. …”
Thesis -
7633
NATbox: a network analysis toolbox in R
Published 2009“…It provides options to (i) impute missing observations in the given data (ii) model FRs and network structure from gene expression profiles using a battery of BSL algorithms and identify robust dependencies using a bootstrap procedure, (iii) present the FRs in the form of acyclic graphs for visualization and investigate its topological properties using network analysis metrics, (iv) retrieve FRs of interest from published literature. …”
Journal article -
7634
A single measurement of combined Direct and indirect MPPT algorithm for mismatch PV module application / Mohd Najib Mohd Hussain
Published 2016“…The use of module integrated converter (MIC) topologies for photovoltaic (PV) system is to harvest the maximum power point of PV module from solar irradiance. …”
Get full text
Thesis -
7635
Optimization of landslide conditioning factors using very high-resolution airborne laser scanning (LiDAR) data at catchment scale
Published 2014“…Landslide susceptibility mapping employs topological, environmental, geological, and hydrological parameters. …”
Article -
7636
Simulation of Linear Feedback Control of D-Statcom for Voltage Sag Mitigation
Published 2006“…The major power quality problems that always occur in power systems are voltage sag, unbalanced voltage and unbalanced current. Various circuit topologies and controls have been developed, aimed at mitigating these power quality problems. …”
Get full text
Thesis -
7637
Deciphering chicken gut microbial dynamics based on high-throughput 16S rRNA metagenomics analyses
Published 2015“…Background: Chicken gut microbiota has paramount roles in host performance, health and immunity. Understanding the topological difference in gut microbial community composition is crucial to provide knowledge on the functions of each members of microbiota to the physiological maintenance of the host. …”
Get full text
Article -
7638
Effects of piston crown profiles on performance of a gasoline homogeneous charge compression ignition engine using computational fluid dynamics
Published 2016“…Using ANSYS software to create a three-dimensional CFD, the mesh creation and specific zone names with dissimilar topologies of each zone were meshed separately. FLUENT was used to model complex combustion phenomena in an HCCI engine. …”
Get full text
Thesis -
7639
Custom Neural networks modelling for semitransparent thin film photovoltaic
Published 2018“…Experiments for different PV panel installation topologies have been conducted for performance analysis. …”
Get full text
Thesis -
7640
Accumulation Of Carbohydrate Reserve And Its Composition In Oil Palm Trunk
Published 2016“…Starch and sugar are the main component of non-structural carbohydrate contained in the oil palm tree. Study on the topological distribution in oil palm trunks showed that the starch was the major component at the top part of the trees. …”
Get full text
Thesis