TRACE AMINE-ASSOCIATED RECEPTOR 9 ROLE IN THERMOREGULATION by Ramilya Murtazina, Evgeniya Efimova, Mikael Mor, Raul Gainetdinov

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Molecular Evolution and Functional Divergence of Trace Amine-Associated Receptors. by Seong-Il Eyun, Hideaki Moriyama, Federico G Hoffmann, Etsuko N Moriyama

“…Trace amine-associated receptors (TAARs) are a member of the G-protein-coupled receptor superfamily and are known to be expressed in olfactory sensory neurons. …”
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Trace Amine Associated Receptor 1 Modulates Behavioral Effects of Ethanol by Laurie J. Lynch, Katherine A. Sullivan, Eric J. Vallender, James K. Rowlett, Donna M. Platt, Gregory M. Miller

“…Here, we assessed whether trace amine associated receptor 1 (TAAR1), a modulator of brain monoamine systems, is involved in the behavioral and reinforcement-related effects of ethanol and whether it could potentially serve as a therapeutic target. …”
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Trace Amine-Associated Receptors as Novel Therapeutic Targets for Immunomodulatory Disorders by Sherri L. Christian, Mark D. Berry

“…Trace amines and their receptors (trace amine-associated receptors; TAARs) are an emerging pharmacological target for the treatment of human disorders. …”
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Molecular basis of human trace amine-associated receptor 1 activation by Gregory Zilberg, Alexandra K. Parpounas, Audrey L. Warren, Shifan Yang, Daniel Wacker

“…Abstract The human trace amine-associated receptor 1 (hTAAR1, hTA1) is a key regulator of monoaminergic neurotransmission and the actions of psychostimulants. …”
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Trace Amine-Associated Receptor 1 Modulates the Locomotor and Sensitization Effects of Nicotine by Ilya Sukhanov, Ilya Sukhanov, Ilya Sukhanov, Mariia Dorofeikova, Antonina Dolgorukova, Artem Dorotenko, Raul R. Gainetdinov, Raul R. Gainetdinov

“…Trace amine-associated receptor 1 (TAAR1) has emerged as a promising target for addiction treatments because it affects dopamine transmission in the mesolimbic pathway. …”
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Deletion of Trace Amine-Associated Receptor 1 Attenuates Behavioral Responses to Caffeine by Michael D. Schwartz, Jeremiah B. Palmerston, Diana L. Lee, Marius C. Hoener, Thomas S. Kilduff

“…Trace amines (TAs), endogenous amino acid metabolites that are structurally similar to the biogenic amines, are endogenous ligands for trace amine-associated receptor 1 (TAAR1), a GPCR that modulates dopaminergic, serotonergic, and glutamatergic activity. …”
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The trace amine-associated receptor 1 modulates methamphetamine’s neurochemical and behavioural effects by Rachel eCotter, Yue ePei, Yue ePei, Liudmila eMus, Anja eHarmeier, Raul eGainetdinov, Marius Christian Hoener, Juan J Canales

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Deregulation of Trace Amine-Associated Receptors (TAAR) Expression and Signaling Mode in Melanoma by Anastasia N. Vaganova, Savelii R. Kuvarzin, Anastasia M. Sycheva, Raul R. Gainetdinov

“…Trace amine-associated receptors (TAARs) interact with amine compounds called “trace amines” which are present in tissues at low concentrations. …”
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Trace Amine Associated Receptor 1 (TAAR1) Modulation of Food Reward by Catherine F. Moore, Catherine F. Moore, Valentina Sabino, Pietro Cottone

“…Dysfunctions in two neurotransmitter systems in the mesocorticolimbic pathway, dopamine and glutamate, are thought to contribute to maladaptive eating behaviors. The trace amine associated receptor 1 (TAAR1) system is a promising therapeutic target for compulsive eating behavior due to the role of TAAR1 in synaptic transmission and in the modulation of dopaminergic and glutamatergic signaling. …”
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Human trace amine-associated receptor TAAR5 can be activated by trimethylamine. by Ivonne Wallrabenstein, Jonas Kuklan, Lea Weber, Sandra Zborala, Markus Werner, Janine Altmüller, Christian Becker, Anna Schmidt, Hanns Hatt, Thomas Hummel, Günter Gisselmann

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Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells by Maria Qatato, Vaishnavi Venugopalan, Alaa Al-Hashimi, Maren Rehders, Aaron D. Valentine, Zeynep Hein, Uillred Dallto, Sebastian Springer, Klaudia Brix

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Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers by Ami Shah, Madison Ratkowski, Alessandro Rosa, Paul Feinstein, Thomas Bozza

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Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function. by Xiao Shi, Nicole A R Walter, John H Harkness, Kim A Neve, Robert W Williams, Lu Lu, John K Belknap, Amy J Eshleman, Tamara J Phillips, Aaron Janowsky

“…Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine, octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 has been implicated in human conditions including obesity, schizophrenia, depression, fibromyalgia, migraine, and addiction. …”
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Trace Amine-Associated Receptors and Monoamine-Mediated Regulation of Insulin Secretion in Pancreatic Islets by Anastasia N. Vaganova, Taisiia S. Shemyakova, Karina V. Lenskaia, Roman N. Rodionov, Charlotte Steenblock, Raul R. Gainetdinov

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Trace Amines and the Trace Amine-Associated Receptor 1: Pharmacology, Neurochemistry and Clinical Implications by Yue ePei, Aman eAsif-Malik, Juan J Canales

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Incretin-like effects of small molecule trace amine-associated receptor 1 agonists by Susanne Raab, Haiyan Wang, Sabine Uhles, Nadine Cole, Ruben Alvarez-Sanchez, Basil Künnecke, Christoph Ullmer, Hugues Matile, Marc Bedoucha, Roger D. Norcross, Nickki Ottaway-Parker, Diego Perez-Tilve, Karin Conde Knape, Matthias H. Tschöp, Marius C. Hoener, Sabine Sewing

“…We investigated trace amine-associated receptor 1 (TAAR1) as a novel target contributing to the control of glucose homeostasis and body weight. …”
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Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5. by Juliane Dinter, Jessica Mühlhaus, Carolin Leonie Wienchol, Chun-Xia Yi, Daniela Nürnberg, Silke Morin, Annette Grüters, Josef Köhrle, Torsten Schöneberg, Matthias Tschöp, Heiko Krude, Gunnar Kleinau, Heike Biebermann

“…Application of 3-iodothyronamine (3-T1AM) results in decreased body temperature and body weight in rodents. The trace amine-associated receptor (TAAR) 1, a family A G protein-coupled receptor, is a target of 3-T1AM. …”
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Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently by Milan Dieris, Daniel Kowatschew, Sigrun I. Korsching

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Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. by Gunnar Kleinau, Juliane Pratzka, Daniela Nürnberg, Annette Grüters, Dagmar Führer-Sakel, Heiko Krude, Josef Köhrle, Torsten Schöneberg, Heike Biebermann

“…Trace amine-associated receptors (TAAR) are rhodopsin-like G-protein-coupled receptors (GPCR). …”
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