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61
Real-time bioacoustics monitoring and automated species identification
Published 2013-07-01“…Traditionally, animal species diversity and abundance is assessed using a variety of methods that are generally costly, limited in space and time, and most importantly, they rarely include a permanent record. …”
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62
Utilising Induced Pluripotent Stem Cells in Neurodegenerative Disease Research: Focus on Glia
Published 2021-04-01“…Particularly in complex human diseases, such as neurodegenerative diseases, iPSCs can give advantages over traditional animal models in that they more accurately represent the human genome. …”
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63
Legal status of pets and pretium affectionis
Published 2020-01-01“…Yet, the mere hint that there is a possibility to finally overcome the traditional "animal = object" concept creates an obligation to review all other civil law provisions and principles de lege lata, and especially de lege ferenda. …”
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64
The participation of public institutions and private sector stakeholders to Devrekani Watershed management planning process
Published 2014-07-01“…Having an environmental plan (EP), supporting the traditional animal husbandry were determined as the highest priority factors by the local administration group and the presence of forests and grasslands and the eco-tourism potential were determined as the highest priority factors for the private sector. …”
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65
Characterization of the rhizophora particleboard as a tissue-equivalent phantom material bonded with bio–based adhesive
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66
Animal models of listeriosis: a comparative review of the current state of the art and lessons learned
Published 2012-03-01“…Newly emerging data about species-specific differences have recently raised concern about the validity of most traditional animal models of listeriosis. However, considerable uncertainty about the best choice of animal model remains. …”
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67
Plant-Based Seafood Analogs
Published 2021-03-01“…The aim is to replace traditional animal-based food with various alternatives, predominantly plant-based analogs. …”
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68
Microfluidics-Based Technologies for the Assessment of Castration-Resistant Prostate Cancer
Published 2024-03-01“…In light of the limitations of traditional animal models and 2D in vitro technologies, the emergence of microfluidics as a tool for prostate cancer research shows tremendous promise. …”
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69
Recapitulating the Cancer Microenvironment Using Bioprinting Technology for Precision Medicine
Published 2021-09-01“…The construction of the cancer microenvironment, including the cell–cell interactions and extracellular matrix (ECM), plays a significant role in the development of drug resistance. Traditional animal models used in drug discovery studies have been associated with feasibility issues that limit the recapitulation of human functions; thus, in vitro models have been developed to reconstruct the human cancer system. …”
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70
Standardisation and international adoption of defined approaches for skin sensitisation
Published 2022-08-01“…This Defined Approach Guideline was the first of its kind for the OECD, and provides an important precedent for regulatory adoption of human biology-relevant new approach methodologies with performances equivalent to, or better than, traditional animal tests. This mini review summarizes the principal features of the defined approaches described in OECD guideline 497.…”
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71
Ethnozoological study of animal based medicines used by traditional healers from south eastern area of Golaghat district, Assam
Published 2023-12-01“…A total six communities viz., Koch, Kalita, Chutia, Ahom, Nath and Mising have been chosen based on semi-structured questionnaire through interactive personal interview and group discussion on the use of traditional animal based medicines by these local people for the treatment of various diseases. …”
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72
iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives
Published 2021-03-01“…The main hurdle for the study of the functional effects of those variants is the need for a specific model that mimics the complex environment of human cardiomyocytes. Traditionally, animal models or transient heterologous expression systems are applied for electrophysiological investigations, each of these models having their limitations. …”
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73
Zebrafish as an Emerging Model for Sarcopenia: Considerations, Current Insights, and Future Directions
Published 2023-11-01“…Despite extensive efforts to study muscle degeneration using traditional animal models, there is still a lack of effective diagnostic tools, precise biomarkers, and treatments for sarcopenia. …”
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74
The adverse outcome pathway for breast cancer: a knowledge management framework bridging biomedicine and toxicology
Published 2023-12-01“…In that regard, the rapid progress of biomedical and toxicological research in recent years now allows the pursuit of new approaches based on non-animal methods that provide greater mechanistic insight than traditional animal models and therefore facilitate the development of Adverse Outcome Pathways (AOPs) for human diseases. …”
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75
Profiling animal toxicants by automatically mining public bioassay data: a big data approach for computational toxicology.
Published 2014-01-01“…In vitro bioassays have been developed and are currently being evaluated as potential alternatives to traditional animal toxicity models. Already, the progress of high throughput screening techniques has resulted in an enormous amount of publicly available bioassay data having been generated for a large collection of compounds. …”
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76
Revolutionizing nephrology research: expanding horizons with kidney-on-a-chip and beyond
Published 2024-03-01“…The superior simulation capabilities compared to traditional animal experiments and two-dimensional cell cultures, making OoC a valuable tool for in vitro research. …”
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77
Amazon rainforest rodents (Proechimys) are resistant to post-stroke epilepsy
Published 2021-08-01“…The present comparative study was conducted to assess (1) stroke-related brain responses 24-h and 30 days after cortical photothrombosis and (2) post-stroke epilepsy between Proechimys rodents and Wistar rats, a traditional animal used for laboratory research. Proechimys group showed smaller volume of ischemic infarction and lesser glial activation than Wistar group. …”
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78
Assessment of quality and chemical composition of continental halophytic grasslands in south-east Europe
Published 2022-03-01“…Continental halophytic grasslands of the Central and South-East Europe are not considered as favourable for arable farming, however, traditional animal husbandry plays a crucial role in maintaining biodiversity and preserving these natural habitats. …”
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79
Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review
Published 2017-10-01“…Bombyx batryticatus (B. batryticatus), a well-known traditional animal Chinese medicine, has been commonly used in China for thousands of years. …”
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80
Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight
Published 2021-08-01“…One outstanding issue is how to maximize scientific output from a limited number of omics datasets from traditional animal models including nematodes, fruitfly, and rodents. …”
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