Drug exposure during pregnancy: Current understanding and approaches to measure maternal-fetal drug exposure by Rachel E. Hudson, Torri D. Metz, Robert M. Ward, Autumn M. McKnite, Elena Y. Enioutina, Catherine M. Sherwin, Kevin M. Watt, Kathleen M. Job

“…Alternative approaches to determine PK have been explored, including physiologically based PK modeling, in vitro methods, and traditional animal models. These alternative approaches along with convenience sampling of tissue or fluid biospecimens can address challenges in studying maternal-fetal pharmacology. …”
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Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes by Fabrizia Milani, Martina Bottoni, Claudia Giuliani, Lorenzo Colombo, Maria Cristina Casiraghi, Paola Sira Colombo, Piero Bruschi, Daniela Erba, Gelsomina Fico

“…Background: Along the Alps, the Alpine diet is considered to be one of the most common nutritional models. Next to traditional animal-based products, spontaneous plants of the territory are collected and eaten. …”
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Nutritional Value of Banded Cricket and Mealworm Larvae by Jagoda Kępińska-Pacelik, Wioletta Biel, Cezary Podsiadło, Grzegorz Tokarczyk, Patrycja Biernacka, Grzegorz Bienkiewicz

“…Insect farming is more ecological than traditional animal farming, as it requires less water and contributes to lower greenhouse gas emissions. …”
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Consumer acceptance of new food trends resulting from the fourth industrial revolution technologies: A narrative review of literature and future perspectives by Abdo Hassoun, Abdo Hassoun, Janna Cropotova, Monica Trif, Alexandru Vasile Rusu, Alexandru Vasile Rusu, Otilia Bobiş, Gulzar Ahmad Nayik, Yash D. Jagdale, Farhan Saeed, Muhammad Afzaal, Parisa Mostashari, Amin Mousavi Khaneghah, Joe M. Regenstein

“…Then, the current knowledge base regarding consumer acceptance of eight traditional animal-proteins alternatives (e.g., plant-based foods and insects) and more recent trends (e.g., cell-cultured meat and 3D-printed foods) will be updated. …”
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Electrochemical Sensing in 3D Cell Culture Models: New Tools for Developing Better Cancer Diagnostics and Treatments by Micaela Oliveira, Pedro Conceição, Krishna Kant, Alar Ainla, Lorena Diéguez

“…Currently, conventional pre-clinical in vitro studies are primarily based on two-dimensional (2D) cell culture models, which are usually limited in mimicking the real three-dimensional (3D) physiological conditions, cell heterogeneity, cell to cell interaction, and extracellular matrix (ECM) present in living tissues. Traditionally, animal models are used to mimic the 3D environment of tissues and organs, but they suffer from high costs, are time consuming, bring up ethical concerns, and still present many differences when compared to the human body. …”
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Perception, Price and Preference: Consumption and Protection of Wild Animals Used in Traditional Medicine. by Zhao Liu, Zhigang Jiang, Hongxia Fang, Chunwang Li, Aizi Mi, Jing Chen, Xiaowei Zhang, Shaopeng Cui, Daiqiang Chen, Xiaoge Ping, Feng Li, Chunlin Li, Songhua Tang, Zhenhua Luo, Yan Zeng, Zhibin Meng

“…Furthermore, awareness of the need for species protection, or "conservation consciousness" was found to play an important role in willingness to accept substitutions for wild animal materials, while traditional animal medicinal materials (TAMs) derived from well-known endangered species, such as bear bile and tiger bone, show relatively higher substitutability. …”
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Translating Scientific Advances in the AOP Framework to Decision Making for Nanomaterials by James D. Ede, Vladimir Lobaskin, Ulla Vogel, Iseult Lynch, Sabina Halappanavar, Shareen H. Doak, Megan G. Roberts, Jo Anne Shatkin

“…However, as the number, diversity and complexity of MNs coming to market continue to grow, assessing their health and environmental risks with traditional animal testing approaches is too time- and cost-intensive to be practical, and is undesirable for ethical reasons. …”
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Impact of plant-based meat alternatives on cattle inventories and greenhouse gas emissions by Jayson L Lusk, Dan Blaustein-Rejto, Saloni Shah, Glynn T Tonsor

“…New plant-based meat (PBM) alternatives that aim to mimic the taste and texture of beef could have significant economic, environmental, and animal welfare impacts if they replace traditional animal-based meats and reduce livestock production. …”
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Exploring Genetic Markers: Mitochondrial DNA and Genomic Screening for Biodiversity and Production Traits in Donkeys by Bingjian Huang, Muhammad Zahoor Khan, Wenqiong Chai, Qudrat Ullah, Changfa Wang

“…Furthermore, genetic markers at the RNA/DNA level have emerged as indispensable tools for enhancing production and reproduction traits in donkeys. Traditional animal breeding approaches based solely on phenotypic traits, such as milk yields, weight, and height, are influenced by both genetic and environmental factors. …”
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Epidermis-on-a-chip system to develop skin barrier and melanin mimicking model by Qiwei Li, Chunyan Wang, Xiaoran Li, Jing Zhang, Zilin Zhang, Keyu Yang, Jun Ouyang, Shaohui Zha, Lifeng Sha, Jianjun Ge, Zaozao Chen, Zhongze Gu

“…In vitro skin models are rapidly developing and have been widely used in various fields as an alternative to traditional animal experiments. However, most traditional static skin models are constructed on Transwell plates without a dynamic three-dimensional (3D) culture microenvironment. …”
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Camel health management and pastoralists’ knowledge and information on zoonoses and food safety risks in Isiolo County, Kenya by Peter Obimbo Lamuka, Francis M. Njeruh, George C. Gitao, Khalif A. Abey

“…Pastoralists self-medicate camels and other livestock (45.8%), which can lead to between over-dosing, under-dosing or wrong drug use. The CBAHWs, traditional animal health service providers (TAHSPs), government veterinary officers and private veterinary officers play a minimum role. …”
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Tolerization for treating neurodegenerative and psychiatric diseases by Peter de Haan

“…In order to identify pSAgs of autoimmune diseases traditionally, animals were immunized with the pSAg protein or peptides derived thereof in the presence of complete Freund's adjuvant (CFA) to enhance the immune response to the pSAg. …”
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A Lightweight Pig Face Recognition Method Based on Automatic Detection and Knowledge Distillation by Ruihan Ma, Hassan Ali, Seyeon Chung, Sang Cheol Kim, Hyongsuk Kim

“…Identifying individual pigs is crucial for efficient breeding, health management, and disease control in modern farming. Traditional animal face identification methods are labor-intensive and prone to inaccuracies, while existing CNN-based pig face recognition models often struggle with high computational demands, large sizes, and reliance on extensive labeled data, which limit their practical application. …”
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Protaetia brevitarsis seulensis larvae ethanol extract inhibits RANKL-stimulated osteoclastogenesis and ameliorates bone loss in ovariectomized mice by Ra-Yeong Choi, In-Woo Kim, Moongi Ji, Man-Jeong Paik, Eu-Jin Ban, Joon Ha Lee, Jae Sam Hwang, HaeYong Kweon, Minchul Seo

“…However, whether Protaetia brevitarsis seulensis (P. brevitarsis) larvae—a traditional animal-derived medicine used in many Asian countries—can inhibit RANKL-induced osteoclast formation and prevent ovariectomy (OVX)-induced bone loss has not been evaluated. …”
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Mealworm larvae (Tenebrio molitor) and crickets (Acheta domesticus) show high total protein in vitro digestibility and can provide good-to-excellent protein quality as determined b... by Laila Hammer, Laila Hammer, Laila Hammer, Diego Moretti, Lychou Abbühl-Eng, Pabiraa Kandiah, Nikolin Hilaj, Reto Portmann, Lotti Egger

“…Due to their similarities to chicken regarding protein composition, total protein in vitro digestibility, and in vitro DIAAS values, TM and AD might be an alternative to traditional animal proteins, provided that suitable processing and food preparation methods are applied. …”
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What do we know about blood-testis barrier? current understanding of its structure and physiology by J. P. Luaces, N. Toro-Urrego, M. Otero-Losada, F. Capani, F. Capani

“…Several junction proteins, like the transmembrane, scaffold and signaling proteins, were identified in the testis using traditional animal models. BTB morphology was analyzed in different physiological conditions as the spermatocyte movement during meiosis, testis development, and seasonal spermatogenesis, but also structural elements, proteins, and BTB permeability were studied. …”
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Movements and oceanographic associations of large pelagic fishes in the North Atlantic Ocean by Braun, Camrin Donald

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Production of Bioactive Porcine Lactoferrin through a Novel Glucose-Inducible Expression System in <i>Pichia pastoris</i>: Unveiling Antimicrobial and Anticancer Functionalities by Chih-Ching Yen, Pei-Ying Wu, Huan Ou-Yang, Hsiao-Ling Chen, Kowit-Yu Chong, Ro-Lin Chang, Chuan-Mu Chen

“…Biotechnological strategies aimed at enhancing LF productivity through microbial expression systems offer substantial cost-effective advantages and exhibit fewer constraints compared to traditional animal bioreactor technologies. This study devised a novel recombinant plasmid, wherein the <i>AOX1</i> promoter was replaced with a glucose-inducible <i>G1</i> promoter (P_G1) to govern the expression of recombinant porcine LF (rpLF) in <i>Pichia pastoris</i> GS115. …”
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PROFESSIONAL DOCUMENTARY AND AMATEUR VIDEOS ABOUT BAD ROADS OF THE RUSSIAN NORTH IN THE CONTEXT OF THE CULTURAL LANDSCAPE / ПРОФЕССИОНАЛЬНОЕ ДОКУМЕНТАЛЬНОЕ КИНО И «НАРОДНОЕ» ВИДЕО... by LAVRENOVA OLGA A. / ЛАВРЕНОВА О.А.

“…Professional documentary about the life of the indigenous peoples of the North includes such topics as migration, everyday traffic practices using traditional animal-drawn transport. The amateur videos dedicated to roads are shot on GoPro, DVRs, smartphones and mainly capture the challenges that drivers of heavy machinery face when struggling to get through mud and melted ice road. …”
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Effect of selected gastrointestinal parasites and viral agents on fecal S100A12 concentrations in puppies as a potential comparative model by Romy M. Heilmann, Aurélien Grellet, Niels Grützner, Shannon M. Cranford, Jan S. Suchodolski, Sylvie Chastant-Maillard, Jörg M. Steiner

“…The role of S100A12 in parasite and viral infections is also difficult to study in traditional animal models due to the lack of S100A12 expression in rodents. …”
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