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241
Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1.
Published 2012-01-01“…PABPN1-sensitive lncRNAs are targeted by the exosome and the RNA helicase MTR4/SKIV2L2; yet, the polyadenylation activity of TRF4-2, a putative human TRAMP subunit, appears to be dispensable for PABPN1-dependent regulation. …”
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242
Sing, Cowboy. The Dreams, Ideas (and Reality) of the Wild West
Published 2013-12-01“…Alongside the conscious exotism of the western, the genre – from the historical point of view, especially in the territory of Czechoslovakia - is able to function in its transformed meaning as a trigger for the tramp movement (and thus can also be seen as one of many roots of the Leftist Avantgarde), as well as a moral and social solution. …”
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243
Toll-like receptor agonist combinations augment mouse T-cell anti-tumor immunity via IL-12- and interferon ß-mediated suppression of immune checkpoint receptor expression
Published 2022-12-01“…Immunization of E.G7-OVA or TRAMP-C1 tumor-bearing mice with peptide or DNA vaccines, co-administered with combination of TLR3 and TLR9 agonists, showed greater suppression of tumor growth. …”
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244
The HDAC inhibitor FK228 enhances adenoviral transgene expression by a transduction-independent mechanism but does not increase adenovirus replication.
Published 2011-01-01“…In some cases, the effects were dramatic, as demonstrated by an increase in CD40L expression by FK228 from 0.3% to 62% when the murine prostate cancer cell line TRAMP-C2 was transduced with Ad[CD40L]. One unexpected finding was that FK228 decreased the transgene expression of an adenoviral vector with the prostate cell-specific PPT promoter in the human prostate adenocarcinoma cell lines LNCaP and PC-346C. …”
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245
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246
Improving Whole Tomato Transformation for Prostate Health: Benign Prostate Hypertrophy as an Exploratory Model
Published 2023-03-01“…Furthermore, the product suppressed carcinogenesis in the TRAMP mouse model of human prostate cancer and interfered with prostate cancer molecular signaling. …”
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247
“It Is Utterly Out of My Expectation”-A Case Inquiry of Teacher Identity of an EFL Teacher in a Chinese Shadow School Setting
Published 2021-10-01“…The results indicate four identities existed: an attendant, a firefighter, a coolie and a tramp. The fundamental predicaments hovering over the green employer encompass an array of contextual factors, including (1) overwhelming anxieties for potential early student leavers; (2) overhuge workload and fluid working schedule; (3) endless non-teaching related commitments; (4) lack of career prospect and development ladder. …”
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248
Residential Mobility di Pinggiran Kota Semarang Jawa Tengah (Studi Kasus Kaum Miskin Kota di Kota Semarang)
Published 2016-08-01“…These were indicated by several factors, either employer or subordinate tramps which cooking foods altogether, unfashionably worn, and behavior of their youngster of asking consideration and advice to the consolidator and status seeker.…”
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249
Parthenogenetic Reproduction in <i>Strumigenys</i> Ants: An Update
Published 2023-02-01“…Of these six thelotykous species, <i>S. emmae</i>, <i>S. membranifera</i> and <i>S. rogeri</i> are known as tramp species. Reproduction without the need to fertilize eggs no doubt offers these species a considerable advantage when establishing colonies in new environments. …”
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250
The Role of SRC-1 in Murine Prostate Cancinogenesis Is Nonessential due to a Possible Compensation of SRC-3/AIB1 Overexpression
Published 2009-01-01“…In this study, we investigated SRC-1 contribution to prostate cancer <i>in vivo</i> by deleting the <i>SRC-1</i> gene in TRAMP mice, which contain the probasin promoter-driven SV40 T/t antigen transgene. …”
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251
RNAa is conserved in mammalian cells.
Published 2010-01-01“…We identified two saRNAs that induced the expression of mouse Cyclin B1 in NIH/3T3 and TRAMP C1 cells, which led to increased phosphorylation of histone H3, a downstream marker for chromosome condensation and entry into mitosis. …”
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252
Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration.
Published 2011-01-01“…Nuclear expression of cleaved Notch2 protein was significantly higher in PC-3 xenografts from PEITC-treated mice and dorsolateral prostates from PEITC-fed TRAMP mice compared with respective control. Because Notch signaling is implicated in epithelial-mesenchymal transition and metastasis, the present study suggests that anti-metastatic effect of PEITC may be augmented by a combination regimen involving a Notch inhibitor.…”
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253
Inhibition of WHSC1 Allows for Reprogramming of the Immune Compartment in Prostate Cancer
Published 2021-08-01“…Prompted by our recent observations that elevated WHSC1, a histone methyltransferase known to promote progression of numerous cancers, can silence antigen processing and presentation in PCa, we performed a single-cell analysis of the intratumoral immune dynamics following in vivo pharmacological inhibition of WHSC1 in mice grafted with TRAMP C2 cells. We observed an increase in cytotoxic T and NK cells accumulation and effector function, accompanied by a parallel remodeling of the myeloid compartment, as well as abundant shifts in key ligand–receptor signaling pathways highlighting changes in cell-to-cell communication driven by WHSC1 inhibition. …”
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254
Trait Plasticity among Invasive Populations of the Ant <i>Technomyrmex brunneus</i> in Japan
Published 2021-09-01“…In this study, we take advantage of an ongoing invasion of the tramp ant <i>Technomyrmex brunneus</i> in Japan to assess trait plasticity in the invasive range of this species. …”
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255
Synthesis of Fluorescent Carbon Dots as Selective and Sensitive Probes for Cupric Ions and Cell Imaging
Published 2019-05-01“…The CDs were used for cell imaging, observed that they were low toxicity to Tramp C1 cells and exhibited blue and green and red fluorescence under a fluorescence microscope. …”
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256
Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer
Published 2014-09-01“…Here, we use a novel lineage-tracing strategy to assess the cell of origin in a diverse range of mouse models, including Nkx3.1+/−; Pten+/−, Pten+/−, Hi-Myc, and TRAMP mice, as well as a hormonal carcinogenesis model. …”
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257
Transcriptome maps of general eukaryotic RNA degradation factors
Published 2019-05-01“…Global analysis suggests that the nuclear surveillance machinery, including the complexes Nrd1/Nab3 and TRAMP4, targets aberrant nuclear RNAs and processes snoRNAs.…”
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258
Tumor-infiltrating Leukocytes Suppress Local Inflammation Via Interleukin-1 Receptor Antagonist in a Syngeneic Prostate Cancer Model
Published 2020-03-01“…Result: We identified a group of pro-inflammatory chemokines associated with a tumorigenic transgenic adenocarcinoma mouse prostate (TRAMP)-C1 cell line. In the tumor microenvironment, the TILs secrete a natural anti-inflammatory factor, interleukin-1 receptor antagonist (IL1RN), which inhibits the functions of pro-inflammatory molecules and likely accounts for tumor type-specific anti-inflammation functions. …”
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259
Perkembangan Kualitas Sumberdaya Manusia Indonesia : Antara Harapan dan Kenyataan
Published 2015-07-01“…Perubahan struktur dentografi yang ada Baru tramp& jelas pada kelompak untur 0 - 9 tahun. Pada saat mendatang jumlah pendudduk masih cukup besar dengan pertumbuhan penduduk masih tetap tinggi, meskipun tidak setinggi saat ini. …”
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260
Robust formation of optimal single spheroids towards cost‐effective in vitro three‐dimensional tumor models
Published 2023-07-01“…In the protocol herein, a rapid and high‐throughput method is discussed for the generation of single spheroids using various cancer cell lines, including brain cancer cells (U87 MG, SEBTA‐027, SF188), prostate cancer cells (DU‐145, TRAMP‐C1), and breast cancer cells (BT‐549, Py230) in 96‐round bottom‐well plates. …”
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