Factor of time in dendritic cell (DC) maturation: short-term activation of DCs significantly improves type 1 cytokine production and T cell responses by Primož Poženel, Kaja Zajc, Urban Švajger

“…Abstract Dendritic cells (DCs) have been intensively studied in correlation to tumor immunology and for the development DC-based cancer vaccines. …”
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Beclin-1: a therapeutic target at the intersection of autophagy, immunotherapy, and cancer treatment by Zhumin Cao, Ke Tian, Yincheng Ran, Haonan Zhou, Lei Zhou, Yana Ding, Xiaowei Tang

“…Finally, we analyzed the possible function of Beclin-1 in tumor immunology and drug sensitivity in cancers. In general, Beclin-1 has a significant impact on regulating autophagy, offering various potentials for medical intervention and altering our understanding of cancer biology.…”
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Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells by Rachel M. Gibbons Johnson, Haidong Dong, Haidong Dong

“…The programmed death-1 (PD-1) and its ligand PD-L1 (B7-H1) signaling pathway has been the focus of much enthusiasm in the fields of tumor immunology and oncology with recent FDA approval of the anti-PD-1 antibodies pembrolizumab and nivolumab and the anti-PD-L1 antibodies durvalumab, atezolimuab, and avelumab. …”
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Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells by Karmel A Allison, Eniko Sajti, Jana G Collier, David Gosselin, Ty Dale Troutman, Erica L Stone, Stephen M Hedrick, Christopher K Glass

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Predictive and Prognostic Molecular Factors in Diffuse Large B-Cell Lymphomas by Stefano A. Pileri, Claudio Tripodo, Federica Melle, Giovanna Motta, Valentina Tabanelli, Stefano Fiori, Maria Carmela Vegliante, Saveria Mazzara, Sabino Ciavarella, Enrico Derenzini

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Clonal evolution in myelodysplastic syndromes by Pedro da Silva-Coelho, Leonie I. Kroeze, Kenichi Yoshida, Theresia N. Koorenhof-Scheele, Ruth Knops, Louis T. van de Locht, Aniek O. de Graaf, Marion Massop, Sarah Sandmann, Martin Dugas, Marian J. Stevens-Kroef, Jaroslav Cermak, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Theo de Witte, Nicole M. A. Blijlevens, Petra Muus, Gerwin Huls, Bert A. van der Reijden, Seishi Ogawa, Joop H. Jansen

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Remarkable immune and clinical value of novel ferroptosis-related genes in glioma by Xiaoyan Gao, Jiazheng Zhao, Litao Jia, Qiushi Zhang

“…Abstract Ferroptosis is a neoteric model of regulated cell death that shows great potential for the understanding of tumor immunology and as a target for therapy. The present study aimed to identify ferroptosis-related differentially expressed genes (DEGs) in glioma and to explore their value through systematic analysis. …”
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CDK3, CDK5 and CDK8 Proteins as Prognostic and Potential Biomarkers in Colorectal Cancer Patients by Wang D, Zhou Y, Hua L, Li J, Zhu N, Liu Y

“…In CRC, CDK3, CDK5 and CDK8 are significantly associated with expression levels of recognized immune infiltrates.Conclusion: CDK3, CDK5 and CDK8 are potential diagnostic markers for CRC; meanwhile, CDK3, CDK5 and CDK8 are potential prognostic markers for CRC; studying the relationship between CDKs and tumor immunology may be helpful for immunotherapy of CRC, and more studies are needed to confirm these results.Keywords: colorectal cancer, cyclin-dependent kinases family, mRNA expression, prognosis, risk score model…”
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The Therapeutic Potential of Tackling Tumor-Induced Dendritic Cell Dysfunction in Colorectal Cancer by Beatriz Subtil, Alessandra Cambi, Daniele V. F. Tauriello, I. Jolanda M. de Vries

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In Silico Approaches: A Way to Unveil Novel Therapeutic Drugs for Cervical Cancer Management by Diana Gomes, Samuel Silvestre, Ana Paula Duarte, Aldo Venuti, Christiane P. Soares, Luís Passarinha, Ângela Sousa

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A Functional GM-CSF Receptor on Dendritic Cells Is Required for Efficient Protective Anti-Tumor Immunity by Emily Charrier, Rémi Vernet, Frank Schwenter, Patricia Luy, Alena Donda, Nicolas Mach

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PIWI-interacting RNAs: Mitochondria-based biogenesis and functions in cancer by Jing-Fen Su, Anthony Concilla, Dian-zheng Zhang, Fang Zhao, Fang-Fang Shen, Hao Zhang, Fu-You Zhou

“…Also, piRNAs play important roles in cancer stemness, drug resistance, and tumor immunology. Results from liquid biopsy analysis of piRNA can be used in both cancer diagnoses and cancer prognoses. …”
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FNC: An Advanced Anticancer Therapeutic or Just an Underdog? by Daria Fayzullina, Rajesh Kumar Kharwar, Arbind Acharya, Anton Buzdin, Nicolas Borisov, Peter Timashev, Ilya Ulasov, Byron Kapomba

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Cuproptosis-related gene index: A predictor for pancreatic cancer prognosis, immunotherapy efficacy, and chemosensitivity by Xufeng Huang, Xufeng Huang, Shujing Zhou, Shujing Zhou, János Tóth, András Hajdu

“…Additionally, correlation analysis revealed major changes in tumor immunology across the high- and low-CRGI groups. …”
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The nucleolus is the site for inflammatory RNA decay during infection by Taeyun A. Lee, Heonjong Han, Ahsan Polash, Seok Keun Cho, Ji Won Lee, Eun A. Ra, Eunhye Lee, Areum Park, Sujin Kang, Junhee L. Choi, Ji Hyun Kim, Ji Eun Lee, Kyung-Won Min, Seong Wook Yang, Markus Hafner, Insuk Lee, Je-Hyun Yoon, Sungwook Lee, Boyoun Park

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Zinc Finger E-Box Binding Homeobox 2 as a Prognostic Biomarker in Various Cancers and Its Correlation with Infiltrating Immune Cells in Ovarian Cancer by Hye-Ran Kim, Choong Won Seo, Sang Jun Han, Jae-Ho Lee, Jongwan Kim

“…Our findings may serve as a potential prognostic biomarker, and provide novel insights into the tumor immunology in OV. Thus, ZEB2 may be a potential diagnostic and therapeutic target in OV.…”
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Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system. by Hirotake Imanishi, Gaku Takibuchi, Toshihiko Kobayashi, Kaori Ishikawa, Kazuto Nakada, Masayuki Mori, Yoshiaki Kikkawa, Keizo Takenaga, Noriko Toyama-Sorimachi, Jun-Ichi Hayashi

“…These observations indicate presence of a novel role of mtDNA in tumor phenotype, and provide new insights into the fields of mitochondrial tumor biology and tumor immunology.…”
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Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases by Gianluca Sferrazza, Marco Corti, Gloria Brusotti, Pasquale Pierimarchi, Caterina Temporini, Annalucia Serafino, Enrica Calleri

“…Much evidence indicates that abnormal Wnt/β-catenin signaling is involved in tumor immunology and the targeting of Wnt/β-catenin pathway has been also proposed as an attractive strategy to potentiate cancer immunotherapy. …”
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Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants by Alice Massacci, Eleonora Sperandio, Lorenzo D’Ambrosio, Mariano Maffei, Fabio Palombo, Luigi Aurisicchio, Gennaro Ciliberto, Matteo Pallocca

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Extracellular vesicles promotes liver metastasis of lung cancer by ALAHM increasing hepatocellular secretion of HGF by Chunyang Jiang, Xu Li, Bingsheng Sun, Na Zhang, Jing Li, Shijing Yue, Xiaoli Hu

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