Response: Commentary: An In Silico–In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients by Michele Mishto, Michele Mishto, Guillermo Rodriguez-Hernandez, Guillermo Rodriguez-Hernandez, Jacques Neefjes, Henning Urlaub, Henning Urlaub, Juliane Liepe

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Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer by Jinyu Wang, Michela Manni, Anne Bärenwaldt, Ronja Wieboldt, Nicole Kirchhammer, Robert Ivanek, Robert Ivanek, Michal Stanczak, Alfred Zippelius, Alfred Zippelius, David König, David König, Natalia Rodrigues Manutano, Heinz Läubli, Heinz Läubli

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Myeloid-derived suppressor cells in cancer: therapeutic targets to overcome tumor immune evasion by Junli Lu, Yiming Luo, Dean Rao, Tiantian Wang, Zhen Lei, Xiaoping Chen, Bixiang Zhang, Yiwei Li, Bifeng Liu, Limin Xia, Wenjie Huang

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IL-25 dampens the growth of human germinal center-derived B-cell non Hodgkin Lymphoma by curtailing neoangiogenesis by Elisa Ferretti, Emma Di Carlo, Emanuela Ognio, Giulio Fraternali-Orcioni, Anna Corcione, Beatrice Belmonte, Jean Louis Ravetti, Claudio Tripodo, Domenico Ribatti, Vito Pistoia

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The complementary roles of STAT3 and STAT1 in cancer biology: insights into tumor pathogenesis and therapeutic strategies by Weiyuan Wang, Melanie Cristina Lopez McDonald, Christine Kim, Mirielle Ma, Zetao (Tommy) Pan, Charlotte Kaufmann, David A. Frank

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Potential Role of Hsp70 and Activated NK Cells for Prediction of Prognosis in Glioblastoma Patients by Dominik Lobinger, Dominik Lobinger, Jens Gempt, Wolfgang Sievert, Wolfgang Sievert, Melanie Barz, Sven Schmitt, Sven Schmitt, Huyen Thie Nguyen, Huyen Thie Nguyen, Stefan Stangl, Stefan Stangl, Caroline Werner, Caroline Werner, Fei Wang, Fei Wang, Zhiyuan Wu, Zhiyuan Wu, Hengyi Fan, Hengyi Fan, Hannah Zanth, Hannah Zanth, Maxim Shevtsov, Maxim Shevtsov, Maxim Shevtsov, Mathias Pilz, Mathias Pilz, Isabelle Riederer, Melissa Schwab, Melissa Schwab, Jürgen Schlegel, Gabriele Multhoff, Gabriele Multhoff

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Dendritic Cell Therapies for Hematologic Malignancies by Matthew Weinstock, Jacalyn Rosenblatt, David Avigan

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The Potential Role of the T2 Ribonucleases in TME-Based Cancer Therapy by Paola Campomenosi, Lorenzo Mortara, Barbara Bassani, Roberto Valli, Giovanni Porta, Antonino Bruno, Francesco Acquati

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Development and Verification of a Prostate Cancer Prognostic Signature Based on an Immunogenomic Landscape Analysis by Hong Cheng, Yi Wang, Chunhui Liu, Tiange Wu, Shuqiu Chen, Ming Chen

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Dendritic cells in cancer immunotherapy clinical trials: are we making progress? by Lisa Helene Butterfield

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The Hippo Pathway Effector Transcriptional Co-activator With PDZ-Binding Motif Correlates With Clinical Prognosis and Immune Infiltration in Colorectal Cancer by Yutong Wang, Hui Nie, Huiling Li, Zhiming Liao, Xuejie Yang, Xiaoyun He, Jian Ma, Jianhua Zhou, Jianhua Zhou, Chunlin Ou, Chunlin Ou

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Differential PD-1/LAG-3 expression and immune phenotypes in metastatic sites of breast cancer by Bettina Sobottka, Holger Moch, Zsuzsanna Varga

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Editorial: Engineered medicines to mitigate resistance to cancer immunotherapy by Kishu Ranjan, Prabhatchandra Dube, Sandeep Kumar Mishra

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Tissue- and Temporal-Dependent Dynamics of Myeloablation in Response to Gemcitabine Chemotherapy by Lydia E. Kitelinger, Eric A. Thim, Sarah Y. Zipkowitz, Richard J. Price, Timothy N. J. Bullock

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A brief review of clinical trials involving manipulation of invariant NKT cells as a promising approach in future cancer therapies by Małgorzata Waldowska, Agnieszka Bojarska-Junak, Jacek Roliński

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Ablative and Immunostimulatory Effects of Histotripsy Ablation in a Murine Osteosarcoma Model by Alayna N. Hay, Khan Mohammad Imran, Alissa Hendricks-Wenger, Jessica M. Gannon, Jacqueline Sereno, Alex Simon, Victor A. Lopez, Sheryl Coutermarsh-Ott, Eli Vlaisavljevich, Irving C. Allen, Joanne L. Tuohy

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Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets? by Anne Huber, Floris Dammeijer, Floris Dammeijer, Joachim G. J. V. Aerts, Joachim G. J. V. Aerts, Heleen Vroman, Heleen Vroman

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The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion by Laura Pinton, Elena Masetto, Marina Vettore, Samantha Solito, Sara Magri, Marta D’Andolfi, Paola Del Bianco, Giovanna Lollo, Jean-Pierre Benoit, Hideho Okada, Aaron Diaz, Alessandro Della Puppa, Susanna Mandruzzato

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Cancer-Associated Fibroblast Heterogeneity: A Factor That Cannot Be Ignored in Immune Microenvironment Remodeling by Pei-Yu Chen, Wen-Fei Wei, Hong-Zhen Wu, Liang-Sheng Fan, Wei Wang

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Activity of tafasitamab in combination with rituximab in subtypes of aggressive lymphoma by Maria Patra-Kneuer, Gaomei Chang, Wendan Xu, Christian Augsberger, Michael Grau, Myroslav Zapukhlyak, Kristina Ilieva, Karin Landgraf, Doris Mangelberger-Eberl, Kasra Yousefi, Philipp Berning, Katrin S. Kurz, German Ott, Pavel Klener, Pavel Klener, Cyrus Khandanpour, Cyrus Khandanpour, Pedro Horna, Jürgen Schanzer, Stefan Steidl, Jan Endell, Christina Heitmüller, Georg Lenz

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