Enhancing immunotherapy outcomes by targeted remodeling of the tumor microenvironment via combined cGAS-STING pathway strategies by Mingqing Huang, Zhuocen Cha, Zhuocen Cha, Rui Liu, Mengping Lin, Naif Abdul Gafoor, Tong Kong, Fei Ge, Wenlin Chen

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The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers by Eline van Diest, Mara J. T. Nicolasen, Lovro Kramer, Jiali Zheng, Patricia Hernández-López, Dennis X. Beringer, Jürgen Kuball, Jürgen Kuball

Subjects: “…tumor immunology…”
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Editorial: Manipulation of immune-vascular crosstalk in solid tumors by Vijay Kumar

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Sites of metastasis and association with clinical outcome in advanced stage cancer patients treated with immunotherapy by Mehmet Asim Bilen, Julie M. Shabto, Dylan J. Martini, Yuan Liu, Colleen Lewis, Hannah Collins, Mehmet Akce, Haydn Kissick, Bradley C. Carthon, Walid L. Shaib, Olatunji B. Alese, Conor E. Steuer, Christina Wu, David H. Lawson, Ragini Kudchadkar, Viraj A. Master, Bassel El-Rayes, Suresh S. Ramalingam, Taofeek K. Owonikoko, R. Donald Harvey

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Context-specific and immune cell–dependent anti-tumor activities of α1-antitrypsin by Ofer Guttman, Gabriella Sara Freixo-Lima, Ziv Kaner, Yotam Lior, Peleg Rider, Eli C. Lewis

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Distinct Spatio-Temporal Dynamics of Tumor-Associated Neutrophils in Small Tumor Lesions by Simon Sody, Mohib Uddin, Anika Grüneboom, André Görgens, André Görgens, Bernd Giebel, Matthias Gunzer, Sven Brandau

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Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models by Julie Lang, Alexis D. Leal, Juan A. Marín-Jiménez, Sarah J. Hartman, Jeremy Shulman, Natalie M. Navarro, Matthew S. Lewis, Anna Capasso, Stacey M. Bagby, Bethlehem W. Yacob, Morgan MacBeth, Brian M. Freed, S. Gail Eckhardt, Kimberly Jordan, Patrick J. Blatchford, Roberta Pelanda, Christopher H. Lieu, Wells A. Messersmith, Todd M. Pitts

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Estrogen receptors and their implications in colorectal carcinogenesis by Francesco eCaiazza, Francesco eCaiazza, Elizabeth J Ryan, Elizabeth J Ryan, Glen eDoherty, Glen eDoherty, Desmond C Winter, Desmond C Winter, Kieran eSheahan, Kieran eSheahan, Kieran eSheahan

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Comprehensive Analysis Identifies and Validates the Tumor Microenvironment Subtypes to Predict Anti-Tumor Therapy Efficacy in Hepatocellular Carcinoma by Haohan Zhang, Yi Yao, Yi Yao, Jie Wu, Jin Zhou, Chen Zhao, Junju He, Bin Xu

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Differential Activation of CD8+ Tumor-Specific Tc1 and Tc2 Cells by an IL-10-Producing Murine Plasmacytoma by Christoph Specht, Hans-Gerd Pauels, Christian Becker, Eckehart Kölsch

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Postoperative Regulatory T-Cells and Natural Killer Cells in Stage I Nonsmall Cell Lung Cancer Underwent Video-assisted Thoracoscopic Lobectomy or Thoracotomy by Sai Zhang, Sai-Bo Pan, Qing-Hua Lyu, Pin Wu, Guang-Ming Qin, Qi Wang, Zhong-Liang He, Xue-Ming He, Ming Wu, Gang Chen

Subjects: “…Natural Killer Cell; Regulatory T-cell; Surgical Invasiveness; Tumor Immunology; Video-assisted Thoracoscopic Lobectomy…”
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Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration by Monica Parodi, Federica Raggi, Davide Cangelosi, Claudia Manzini, Mirna Balsamo, Fabiola Blengio, Alessandra Eva, Luigi Varesio, Gabriella Pietra, Gabriella Pietra, Lorenzo Moretta, Maria Cristina Mingari, Maria Cristina Mingari, Maria Cristina Mingari, Massimo Vitale, Maria Carla Bosco

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Identification of hub genes correlated with tumor-associated M1-like macrophage infiltration in soft tissue sarcomas by Minchao Lv, Feixiong He, Jinku Guo, Zhenxin Zheng, Wei Wang, Jun Xie

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A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma by Zaoqu Liu, Yuyuan Zhang, Chengcheng Shi, Xueliang Zhou, Kaihao Xu, Dechao Jiao, Zhenqiang Sun, Xinwei Han

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ALKBH5 regulates arginase 1 expression in MDSCs and their immunosuppressive activity in tumor-bearing host by Lili Feng, Min Li, Jie Ma, Wenxin Wang, Shengjun Wang, Zhenwei Mao, Yue Zhang

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Tissue adaptation of CD4 T lymphocytes in homeostasis and cancer by Marina V. A. Pereira, Marina V. A. Pereira, Rômulo G. Galvani, Triciana Gonçalves-Silva, Zilton Farias Meira de Vasconcelo, Adriana Bonomo

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Low GILT expression is associated with poor patient survival in diffuse large B-cell lymphoma by Hannah ePhipps-Yonas, Hannah ePhipps-Yonas, Haiyan eCui, Noemi eSebastiao, Patrick S. Brunhoeber, Ellen eHaddock, Martin J. Deymier, Wolfram eKlapper, Lonnie eLybarger, Lonnie eLybarger, Denise eRoe, Denise eRoe, Karen Taraszka Hastings, Karen Taraszka Hastings, Karen Taraszka Hastings

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HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions by Adam C. Soloff, Adam C. Soloff, Katherine E. Jones, Amy A. Powers, Pranav Murthy, Yue Wang, Yue Wang, Kira L. Russell, Miranda Byrne-Steele, Amanda W. Lund, Jian-Min Yuan, Jian-Min Yuan, Sara E. Monaco, Jian Han, Rajeev Dhupar, Rajeev Dhupar, Michael T. Lotze, Michael T. Lotze, Michael T. Lotze

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Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells by Constanza Rodriguez, Cintia L. Araujo Furlan, Jimena Tosello Boari, Sabrina N. Bossio, Santiago Boccardo, Laura Fozzatti, Fernando P. Canale, Cristian G. Beccaria, Nicolás G. Nuñez, Danilo G. Ceschin, Eliane Piaggio, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodríguez

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Editorial: Versatile Roles for B Cells in Tumor Immunity by Peter Brossart

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