Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer by Biagio Ricciuti, Sasha Kravets, Suzanne E. Dahlberg, Renato Umeton, Adem Albayrak, Safiya J. Subegdjo, Bruce E. Johnson, Mizuki Nishino, Lynette M. Sholl, Mark M. Awad

Subjects: “…Tumor mutational burden…”
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Validity and utility of blood tumor mutational burden (bTMB) is dependent on circulating tumor DNA (ctDNA) shed: SCRUM-Japan MONSTAR-SCREEN by Saori Mishima, Yoshiaki Nakamura, Hanna Tukachinsky, Hiroya Taniguchi, Shigenori Kadowaki, Ken Kato, Eiji Oki, Taroh Satoh, Daisuke Aoki, Kentaro Yamazaki, Taito Esaki, Makoto Ueno, Tomohiro Nishina, Yu Sunakawa, Tadamichi Denda, Hideaki Bando, Naomi Kuramoto, Satoshi Horasawa, Hikaru Abutani, Jessica K. Lee, Russell W. Madison, Geoffrey R. Oxnard, Takayuki Yoshino

Subjects: “…Tumor mutational burden…”
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Relationship between tumor mutational burden and maximum standardized uptake value in 2-[18F]FDG PET (positron emission tomography) scan in cancer patients by Amin Haghighat Jahromi, Donald A. Barkauskas, Matthew Zabel, Aaron M. Goodman, Garret Frampton, Mina Nikanjam, Carl K. Hoh, Razelle Kurzrock

Subjects: “…Tumor mutational burden…”
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Tumor mutational burden is not predictive of cytotoxic chemotherapy response by Mina Nikanjam, Paul Riviere, Aaron Goodman, Donald A. Barkauskas, Garrett Frampton, Razelle Kurzrock

Subjects: “…tumor mutational burden…”
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Research Progress on Predictive Biomarkers of Immunotherapy Efficacy
in Non-small Cell Lung Cancer by Tiansheng SUN, Zhang CHEN, Kunchen WEI, Hao TANG

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Review of Immunogenomics and the Role of Tumor Mutational Burden as a Biomarker for Immunotherapy Response by Javier Ros, Iosune Baraibar, Ana Vivancos, Jordi Rodon

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Cancer Risks in Solid Organ Transplant Recipients: Results from a Comprehensive Analysis of 72 Cohort Studies by Zhenyu Huo, Caichen Li, Xin Xu, Fan Ge, Runchen Wang, Yaokai Wen, Haoxin Peng, Xiangrong Wu, Hengrui Liang, Guilin Peng, Run Li, Danxia Huang, Ying Chen, Ran Zhong, Bo Cheng, Shan Xiong, Weiyi Lin, Jianxing He, Wenhua Liang

Subjects: “…solid organ transplantation; tumor mutational burden; cancer risk…”
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CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden by Ian Yi-Feng Chang, Hong-Chieh Tsai, Chia-Hua Chen, Hsiu-Chi Chen, Chia-Wen Huang, Gerald F. Cox, Fang-Min Huang, You-Yu Lin, Ko-Ting Chen, Ya-Jui Lin, Kuo-Chen Wei

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Tumor mutational burden as a predictive biomarker for checkpoint inhibitor immunotherapy by Mark Lee, Robert M. Samstein, Cristina Valero, Timothy A. Chan, Luc G.T. Morris

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Identification and Validation of Ferroptosis-Related Subtypes and a Predictive Signature in Hepatocellular Carcinoma by Zheng C, Peng Y, Wang H, Wang Y, Liu L, Zhao Q

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High tumor mutational burden assessed through next-generation sequencing predicts favorable survival in microsatellite stable metastatic colon cancer patients by Annabella Di Mauro, Mariachiara Santorsola, Giovanni Savarese, Roberto Sirica, Monica Ianniello, Alessia Maria Cossu, Anna Ceccarelli, Francesco Sabbatino, Marco Bocchetti, Anna Chiara Carratù, Francesca Pentimalli, Gerardo Ferrara, Guglielmo Nasti, Michele Caraglia, Alessandro Ottaiano

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Machine learning to improve interpretability of clinical, radiological and panel-based genomic data of glioma grade 4 patients undergoing surgical resection by Michele Dal Bo, Maurizio Polano, Tamara Ius, Federica Di Cintio, Alessia Mondello, Ivana Manini, Enrico Pegolo, Daniela Cesselli, Carla Di Loreto, Miran Skrap, Giuseppe Toffoli

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Complete and Durable Response to Nivolumab in Recurrent Poorly Differentiated Pancreatic Neuroendocrine Carcinoma with High Tumor Mutational Burden by Nai-Wen Kang, Kien-Thiam Tan, Chien-Feng Li, Yu-Hsuan Kuo

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Relationship between tumor mutational burden, gene mutation status, and clinical characteristics in 340 cases of lung adenocarcinoma by Kai Ma, Fengxiang Huang, Yin Wang, Yan Kang, Qilong Wang, Jiaqi Tang, Panfeng Sun, Jiaojiao Lou, Ruiping Qiao, Jiming Si, Jian Cao, Lijun Miao

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Identification and validation of inflammatory subtypes in intrahepatic cholangiocellular carcinoma by Biao Gao, Yafei Wang, Xianzhou Zhang, Hao Jiang, Feng Han, Chonghui Li, Shichun Lu

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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden by Zachary R. Chalmers, Caitlin F. Connelly, David Fabrizio, Laurie Gay, Siraj M. Ali, Riley Ennis, Alexa Schrock, Brittany Campbell, Adam Shlien, Juliann Chmielecki, Franklin Huang, Yuting He, James Sun, Uri Tabori, Mark Kennedy, Daniel S. Lieber, Steven Roels, Jared White, Geoffrey A. Otto, Jeffrey S. Ross, Levi Garraway, Vincent A. Miller, Phillip J. Stephens, Garrett M. Frampton

Subjects: “…Tumor mutational burden…”
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Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival by Mary A. Wood, Benjamin R. Weeder, Julianne K. David, Abhinav Nellore, Reid F. Thompson

Subjects: “…Tumor mutational burden…”
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A Combined Two-mRNA Signature Associated With PD-L1 and Tumor Mutational Burden for Prognosis of Lung Adenocarcinoma by Congkuan Song, Congkuan Song, Zhiquan Wu, Qingwen Wang, Qingwen Wang, Yujin Wang, Yujin Wang, Zixin Guo, Zixin Guo, Sheng Li, Sheng Li, Weidong Hu, Weidong Hu

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A novel RNA modification prognostic signature for predicting the characteristics of the tumor microenvironment in gastric cancer by Qiangan Jing, Qiangan Jing, Hongfeng Yao, Huanjuan Li, Chen Yuan, Jiayu Hu, Ping Zhang, Yunyi Wu, Yi Zhou, Xueying Ren, Chen Yang, Guojie Lei, Jing Du, Xia Ke, Jun Xia, Xiangmin Tong, Xiangmin Tong

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Tumor mutational burden assessment and standardized bioinformatics approach using custom NGS panels in clinical routine by Célia Dupain, Tom Gutman, Elodie Girard, Choumouss Kamoun, Grégoire Marret, Zahra Castel-Ajgal, Marie-Paule Sablin, Cindy Neuzillet, Edith Borcoman, Ségolène Hescot, Céline Callens, Olfa Trabelsi-Grati, Samia Melaabi, Roseline Vibert, Samantha Antonio, Coralie Franck, Michèle Galut, Isabelle Guillou, Maral Halladjian, Yves Allory, Joanna Cyrta, Julien Romejon, Eleonore Frouin, Dominique Stoppa-Lyonnet, Jennifer Wong, Christophe Le Tourneau, Ivan Bièche, Nicolas Servant, Maud Kamal, Julien Masliah-Planchon

Subjects: “…Tumor mutational burden…”
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